Patents by Inventor John Ralph
John Ralph has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240276985Abstract: Antimicrobial diferulates, compositions containing same, and uses of same for inhibiting growth of microorganisms. The antimicrobial diferulates can be used alone or in combination with other antimicrobial agents to inhibit growth of microorganisms such as fungi, oomycetes, and other microorganisms having a glucan-containing cell wall. The antimicrobial diferulates can be included in pharmaceutical compositions for treatment of animals or included in agricultural compositions for treatment of plants, crops, and soils.Type: ApplicationFiled: April 18, 2024Publication date: August 22, 2024Applicant: Wisconsin Alumni Research FoundationInventors: Jeff S. Piotrowski, Fachuang Lu, Mehdi Kabbage, John Ralph, Robert C. Landick
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Patent number: 11985974Abstract: Antimicrobial diferulates, compositions containing same, and uses of same for inhibiting growth of microorganisms. The antimicrobial diferulates can be used alone or in combination with other antimicrobial agents to inhibit growth of microorganisms such as fungi, oomycetes, and other microorganisms having a glucan-containing cell wall. The antimicrobial diferulates can be included in pharmaceutical compositions for treatment of animals or included in agricultural compositions for treatment of plants, crops, and soils.Type: GrantFiled: August 27, 2021Date of Patent: May 21, 2024Assignee: Wisconsin Alumni Research FoundationInventors: Jeff S. Piotrowski, Fachuang Lu, Mehdi Kabbage, John Ralph, Robert C. Landick
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Patent number: 11981904Abstract: The invention is directed to BAHD acyltransferase enzymes, nucleic acids encoding BAHD acyltransferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of BAHD acyltransferase RNA; expression cassettes, plant cells, and plants that have or encode such nucleic acids and enzymes; and methods of making and using such nucleic acids, enzymes, expression cassettes, cells, and plants.Type: GrantFiled: November 8, 2019Date of Patent: May 14, 2024Assignees: Wisconsin Alumni Research Foundation, The University of British ColumbiaInventors: Steven D. Karlen, Rebecca Anne Smith, John Ralph, Emily Beebe, Craig Bingman, Brian Fox, Shawn Mansfield, Heather Mackay, Hoon Kim, Yaseen Mottiar, Faride Unda
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Publication number: 20240042733Abstract: In a packaging material that is, or includes, a laminate, the laminate includes first and second webs that are joined to one another. The first web includes a metallic layer on a second layer. The metallic layer is positioned between the second layer and the second web. Indicium is defined in at least the metallic layer. The packaging material is configured so that the indicium is visible from a first side of the packaging material, and the indicium is typically not visible from a second side of the packaging material. The indicium can be at least partially defined by holes in the metallic layer. The visibility of the indicium may be enhanced by the laminate including material that is a different color than the metallic layer, and the different color being at least partially visible through the indicium.Type: ApplicationFiled: October 23, 2023Publication date: February 8, 2024Inventors: Louis Douglas Smith, JR., John Ralph Bumgardner, Jeffery Allen Boekeloo, Rajesh Suryanarayanan
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Publication number: 20230406431Abstract: A dropper seatpost assembly is disclosed. The dropper seatpost assembly includes a lower post and an upper post configured to telescopically move with respect to the lower post. The dropper seatpost assembly also includes a translating mechanism configured to maintain an orientation such as a lateral orientation, a rotational orientation, or both a lateral orientation and a rotational orientation of the upper post with respect to the lower post as the upper post telescopically moves with respect to the lower post, the translating mechanism comprising two or more vertically offset features.Type: ApplicationFiled: August 30, 2023Publication date: December 21, 2023Applicant: Fox Factory, Inc.Inventors: Joshua COAPLEN, John Ralph KIFFMEYER
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Patent number: 11813820Abstract: In a packaging material that is, or includes, a laminate, the laminate includes first and second webs that are joined to one another. The first web includes a metallic layer on a second layer. The metallic layer is positioned between the second layer and the second web. Indicium is defined in at least the metallic layer. The packaging material is configured so that the indicium is visible from a first side of the packaging material, and the indicium is typically not visible from a second side of the packaging material. The indicium can be at least partially defined by holes in the metallic layer. The visibility of the indicium may be enhanced by the laminate including material that is a different color than the metallic layer, and the different color being at least partially visible through the indicium.Type: GrantFiled: September 21, 2018Date of Patent: November 14, 2023Assignee: Printpack Illinois, Inc.Inventors: Louis Douglas Smith, Jr., John Ralph Bumgardner, Jeffery Allen Boekeloo, Rajesh Suryanarayanan
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Patent number: 11807875Abstract: The invention relates to feruloyl-CoA:monolignol transferase enzymes and nucleic acids encoding the feruloyl-CoA:monolignol transferase enzymes. The enzymes and/or the nucleic acids enable incorporation of monolignol ferulates into the lignin of plants. The monolignol ferulates include, for example, p-coumaryl ferulate, coniferyl ferulate, and/or sinapyl ferulate.Type: GrantFiled: November 30, 2020Date of Patent: November 7, 2023Assignee: Wisconsin Alumni Research FoundationInventors: John Ralph, Steven D. Karlen, Rebecca Anne Smith, Brian Fox, Emily Beebe, Craig Bingman
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Patent number: 11807876Abstract: The invention is directed to p-coumaroyl-CoA:monolignol transferase enzymes, nucleic acids encoding p-coumaroyl-CoA:monolignol transferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of p-coumaroyl-CoA:monolignol transferase RNA; expression cassettes, plant cells, and plants that have or encode such nucleic acids and enzymes; and methods of making and using such nucleic acids, enzymes, expression cassettes, cells, and plants.Type: GrantFiled: November 30, 2020Date of Patent: November 7, 2023Assignee: Wisconsin Alumni Research FoundationInventors: John Ralph, Steven D. Karlen, Rebecca Anne Smith, Brian Fox, Emily Beebe, Craig Bingman
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Patent number: 11782946Abstract: An operations integration processor mapping information in a language-independent data format to a tag format for integration with a tag-based control and data acquisition system. The operations integration processor receives a response from a web service and parses the response to identify one or more attribute-value pairs contained in the response. The response contains information in a language-independent data format different than a tag format. The processor maps the parsed response to one or more tags, which have at least one of a name and a value based on the information provided in the response associated with them.Type: GrantFiled: August 31, 2018Date of Patent: October 10, 2023Assignee: AVEVA SOFTWARE, LLCInventors: Yuk Ming Fong, Alvaro Martinez, John Ralph Bartlett
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Patent number: 11745817Abstract: A dropper seatpost assembly is disclosed. The dropper seatpost assembly includes a lower post and an upper post configured to telescopically move with respect to the lower post. The dropper seatpost assembly also includes a translating mechanism configured to maintain an orientation such as a lateral orientation, a rotational orientation, or both a lateral orientation and a rotational orientation of the upper post with respect to the lower post as the upper post telescopically moves with respect to the lower post, the translating mechanism comprising two or more vertically offset features.Type: GrantFiled: May 27, 2021Date of Patent: September 5, 2023Assignee: Fox Factory, Inc.Inventors: Joshua Coaplen, John Ralph Kiffmeyer
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Publication number: 20230203461Abstract: The present application relates to nucleic acids encoding polypeptides with ?-etherase activity; polypeptides with ?-etherase activity; vectors comprising said nucleic acids for the production of recombinant ?-etherase; cells, for example microbial cells transformed with nucleic acids encoding ?-etherase activity and vectors, including nucleic acids encoding ?-etherases; a composition comprising ?-etherases suitable for processing lignocellulose and a method that uses ?-etherases or compositions comprising ?-etherases in the processing of lignocellulose and related polysaccharides.Type: ApplicationFiled: January 9, 2021Publication date: June 29, 2023Applicants: The University of York, Wisconsin Alumni Research FoundationInventors: Neil Bruce, Nicola Oates, John Ralph
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Publication number: 20220411453Abstract: A method of completely dissolving lignocellulosic biomass. The method includes the steps of dissolving a sample of biomass in an aqueous solution of strong acid and an amine-thiol to yield a first solution. A method for measuring lignin concentration in biomass via absorbance of the first solution at a wavelength of about 283 nm by comparing the measured absorbance to a standard curve of absorbance values made from solutions of known lignin concentration.Type: ApplicationFiled: June 9, 2022Publication date: December 29, 2022Inventors: Fachuang Lu, John Ralph
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Patent number: 11493287Abstract: Self-regulating thermal insulation includes one or more thermal actuators that expand and contract in response to changes in temperature adjacent the thermal insulation, thereby automatically changing the thermal resistance of the thermal insulation. In this manner, a self-regulating thermal insulation may be configured to locally adjust in response to local changes in temperature of a part being insulated, for example, during curing or some other manufacturing process. Such self-regulating thermal insulation may be configured to respond to temperature changes without feedback control systems, power, or human intervention.Type: GrantFiled: June 28, 2019Date of Patent: November 8, 2022Assignee: The Boeing CompanyInventors: John Ralph Hull, Cameron K. Chen
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Patent number: 11447754Abstract: Enzymes for depolymerizing lignin. The enzymes include dehydrogenases, ?-etherases, and glutathione lyases. The dehydrogenases can comprise one or more or LigD, LigO, LigN, and LigL. The ?-etherases can comprise one or more of LigE, LigF, LigP, and BaeA. The glutathione lyases can comprise any one or more of LigG and a number of non-stereospecific, optionally recombinant glutathione lyases derived from Sphingobium sp. SYK-6, Novosphingobium aromaticivorans, Escherichia coli, Streptococcus sanguinis, Phanerochaete chrysosporium, and other microorganisms. The enzymes can be combined in compositions and/or used in methods of processing lignin or other aromatic compounds in vitro.Type: GrantFiled: September 30, 2020Date of Patent: September 20, 2022Assignee: Wisconsin Alumni Research FoundationInventors: Timothy James Donohue, Daniel Leo Gall, Wayne S. Kontur, Hoon Kim, John Ralph, Daniel R. Noguera, Brian Fox, Craig Bingman
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Patent number: 11414372Abstract: Methods of detecting and, optionally, determining a level of incorporation of monolignol ester conjugates into lignin. The methods include derivatizing lignin to acylate at least a portion of free phenolic and aliphatic hydroxyls and to halogenate at least a portion of benzylic alcohols present in the lignin to yield derivatized lignin, treating the derivatized lignin with a reducing agent to cleave at least a portion of the derivatized lignin to yield lignin cleavage products, acetylating at least a portion of free hydroxyl groups in the lignin cleavage products with a labeled acetylation agent to yield labeled lignin fragments, and detecting the labeled lignin fragments.Type: GrantFiled: January 21, 2019Date of Patent: August 16, 2022Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: John Ralph, Steven D Karlen, Fachuang Lu, Dharshana Padmakshan
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Patent number: 11409760Abstract: An operations integration processor generating tag names from an array of objects in a language-independent data format different than a tag format for integration with a tag-based control and data acquisition system. The operations integration processor receives a response from a web service and parses the response to identify one or more objects and corresponding values in the array contained in the response. The response includes an array of objects and is in a language-independent data format different than a tag format. The processor configures a selected object of the array to act as a unique index for the array of objects and generates one or more tag names from the parsed response. The tag names each represent a tag having at least one of an object and a value associated with it based on the information provided in the response. The generated tag names include the selected object in an array index part thereof.Type: GrantFiled: August 31, 2018Date of Patent: August 9, 2022Assignee: AVEVA SOFTWARE, LLCInventors: Alvaro Martinez, John Ralph Bartlett, Yuk Ming Fong
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Patent number: 11326178Abstract: The invention relates to nucleic acids encoding a p-coumaroyl-CoA:monolignol transferase and to inhibitory nucleic acids adapted to inhibit the expression and/or translation of a p-coumaroyl-CoA:monolignol transferase RNA. Inhibition of p-coumaroyl-CoA:monolignol transferase in plants improves the incorporation of monolignol ferulates into the lignin of plants, giving rise to plant biomass that is more easily processed into useful products such as paper and biofuels.Type: GrantFiled: August 14, 2019Date of Patent: May 10, 2022Assignees: Wisconsin Alumni Research Foundation, Board of Trustees of Michigan State University, The Board of Trustees of Illinois State UniversityInventors: Curtis Wilkerson, John Ralph, Saunia Withers, John Sedbrook
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Patent number: 11318520Abstract: A method of forming sheet metal skins of the inner fixed structure of a blocker door thrust reverser assembly having convex and concave curvatures. The method includes plastically stretching a sheet of metal about a mandrel having a chordwise central first axis to form a substantially convex shape. The method further includes the addition of features after the substantially convex shape is formed to facilitate plastically stretching a portion or portions of the substantially convex shape into a substantially concave shape about an axis that is substantially parallel to the chordwise central first axis.Type: GrantFiled: December 30, 2018Date of Patent: May 3, 2022Inventor: John Ralph Stewart, III
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Publication number: 20220061321Abstract: Antimicrobial diferulates, compositions containing same, and uses of same for inhibiting growth of microorganisms. The antimicrobial diferulates can be used alone or in combination with other antimicrobial agents to inhibit growth of microorganisms such as fungi, oomycetes, and other microorganisms having a glucan-containing cell wall. The antimicrobial diferulates can be included in pharmaceutical compositions for treatment of animals or included in agricultural compositions for treatment of plants, crops, and soils.Type: ApplicationFiled: August 27, 2021Publication date: March 3, 2022Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATIONInventors: Jeff S. Piotrowski, Fachuang Lu, Mehdi Kabbage, John Ralph, Robert C. Landick
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Publication number: 20220002744Abstract: The invention is directed to BAHD acyltransferase enzymes, nucleic acids encoding BAHD acyltransferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of BAHD acyltransferase RNA; expression cassettes, plant cells, and plants that have or encode such nucleic acids and enzymes; and methods of making and using such nucleic acids, enzymes, expression cassettes, cells, and plants.Type: ApplicationFiled: November 8, 2019Publication date: January 6, 2022Applicants: WISCONSIN ALUMNI RESEARCH FOUNDATION, THE UNIVERSITY OF BRITISH COLUMBIAInventors: Steven D. Karlen, Rebecca Anne Smith, John Ralph, Emily Beebe, Craig Bingman, Brian Fox, Shawn Mansfield, Heather Mackay, Hoon Kim, Yaseen Mottiar, Faride Unda