Patents by Inventor John Randle

John Randle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL FORMULATIONS CONTAINING P2Y14 ANTAGONISTS
    Publication number: 20220202799
    Abstract: The invention provides formulations containing a P2Y14 antagonist, such as the naphthoic acid derivative PPTN, and an agent that increases the solubility of the P2Y 14 antagonist in an aqueous medium. The invention also provides methods of using the formulations to treat kidney disorders and conditions associated with renal inflammation.
    Type: Application
    Filed: April 13, 2020
    Publication date: June 30, 2022
    Inventors: John Randle, Yadan Chen
  • TREATING SEIZURES USING ICE INHIBITORS
    Publication number: 20150190404
    Abstract: This invention relates to methods and compositions for treating or preventing seizures.
    Type: Application
    Filed: December 18, 2014
    Publication date: July 9, 2015
    Inventors: Annamaria Vezzani, John Randle
  • Methods for monitoring IL-18
    Publication number: 20090215856
    Abstract: This invention relates to methods for monitoring IL-18.
    Type: Application
    Filed: April 24, 2009
    Publication date: August 27, 2009
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Amit Roy, Matthew W. Harding, John Alam, John Randle
  • Treating seizures using ice inhibitors
    Publication number: 20060128696
    Abstract: This invention relates to methods and compositions for treating or preventing seizures.
    Type: Application
    Filed: May 16, 2005
    Publication date: June 15, 2006
    Inventors: Annamaria Vezzani, John Randle
  • Treatment of diseases using ICE inhibitors
    Publication number: 20050267101
    Abstract: This invention relates to methods and compositions for treating autoinflammatory diseases. The invention also assays for evaluating the ability of an ICE inhibitor to treat autoinflammatory diseases.
    Type: Application
    Filed: May 27, 2005
    Publication date: December 1, 2005
    Inventor: John Randle
  • Treating infectious diseases using ice inhibitors
    Publication number: 20050233974
    Abstract: This invention relates to methods and compositions for treating infectious and other diseases, particularly of the eye, by administering an ICE inhibitor. This invention also relates to methods for treating injuries, allergies, chemical irritations, or burns of the eye by administering an ICE inhibitor.
    Type: Application
    Filed: December 1, 2004
    Publication date: October 20, 2005
    Inventors: John Randle, George Ku, Linda Hazlett
  • Methods for monitoring IL-18
    Publication number: 20050209162
    Abstract: This invention relates to methods for monitoring IL-18.
    Type: Application
    Filed: November 10, 2004
    Publication date: September 22, 2005
    Inventors: Amit Roy, Matthew Harding, John Alam, John Randle
  • Use of riluzole in the treating acoustic traumas
    Patent number: 6660757
    Abstract: The invention concerns the use of riluzole or one of its pharmaceutically acceptable salts for preventing and/or treating acoustic traumas and, in particular, different types of deafness and tinnitus.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: December 9, 2003
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Jean-Marie Stutzmann, John Randle
  • Use of riluzole in the treating acoustic traumas
    Publication number: 20020004516
    Abstract: The invention concerns the use of riluzole or one of its pharmaceutically acceptable salts for preventing and/or treating acoustic traumas and, in particular, different types of deafness and tinnitus.
    Type: Application
    Filed: June 15, 2001
    Publication date: January 10, 2002
    Inventors: Jean-Marie Stutzmann, John Randle