Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. Multiple “correct” answers are integrated into the learning system to allow individualized learning experiences in which navigation through the system is at a pace controlled by the learner.

Abstract: Embodiments of the present invention relate to apparatus, systems and methods for adding a humidity-controlled system to a thermogravimetric instrument. A humidity-controlled controlled chamber incorporates a housing, a humidifier, a sample chamber, a reference chamber, Peltier devices, humidity and temperature sensors, and gas transmission lines into a single unit. This single unit along with an electronic control unit and mass flow controllers provide a humidity-controlled system designed to control the atmosphere of TGA sample and reference chambers simultaneously. A system comprising an arm, motorized linear actuator an electric control unit, allows a humidity-controlled chamber to be automatically opened and closed, in turn, allowing reference and sample chambers to automatically be accessed.

Abstract: A heterocyclic inhibitor having the formula I, with the variables defined herein, which is useful for treating inflammatory and other physiological disorders in which PKC-theta isoform plays a role:

Abstract: Embodiments of the present invention relate to apparatus, systems and methods for adding a humidity-controlled system to a thermogravimetric instrument. A humidity-controlled chamber incorporates a housing, a humidifier, a sample chamber, a reference chamber, Peltier devices, humidity and temperature sensors, and gas transmission lines into a single unit. This single unit along with an electronic control unit and mass flow controllers provide a humidity-controlled system designed to control the atmosphere of TGA sample and reference chambers simultaneously. A system comprising an arm, motorized linear actuator and electronic control unit, allows a humidity-controlled chamber to be automatically opened and closed, in turn, allowing reference and sample chambers to automatically be accessed.

Abstract: The invention is directed to physiologically active compounds of the general formula (Ix) and compositions containing such compounds, and their prodrugs, and pharmaceutically acceptable salts and solvates of such compounds and their prodrugs, as well as to novel compounds within the scope of formula (Ix), and to processes for their preparation. Such compounds and compositions have valuable pharmaceutical properties, in particular the ability to inhibit kinases.

Abstract: The present invention relates to apparatus, systems, and methods for opening an autosampler sealed sample pan prior to TGA testing. The sealed sample pan comprises a pan, cover, and bail. A notch is formed in the seal sample pan cover. The cover can be opened by applying a concentrated force to the inside of the notch with a punch element integrated into the autosampler. This causes the center disk portion of the cover to be partially sheared and the sealed sample pan to be opened. It also prevents the punch element from touching the sample. A force sensor is used to determine if the cover has been opened. If the cover has been opened, then the sample pan is loaded to the TGA balance. If the cover has not been opened, the autosampler will not load the pan and will automatically move to the next sealed sample pan.

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. Multiple “correct” answers are integrated into the learning system to allow individualized learning experiences in which navigation through the system is at a pace controlled by the learner.

Abstract: A system is disclosed that provides a goal based learning system utilizing a rule based expert training system to provide a cognitive educational experience. The system provides the user with a simulated environment that presents a business opportunity to understand and solve optimally. Mistakes are noted and remedial educational material presented dynamically to build the necessary skills that a user requires for success in the business endeavor. The system utilizes an artificial intelligence engine driving individualized and dynamic feedback with synchronized video and graphics used to simulate real-world environment and interactions. Multiple "correct" answers are integrated into the learning system to allow individualized learning experiences in which navigation through the system is at a pace controlled by the learner.