Patents by Inventor John Richard LEE

John Richard LEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF DETECTING CELL-FREE DNA IN BIOLOGICAL SAMPLES
    Publication number: 20240026456
    Abstract: The present disclosure is directed to methods of detecting cell-free DNA (cfDNA) in biological samples and using it to quantify organ damage and identify pathogens. In some aspects, the biological samples are from patients who have undergone solid-organ transplantation. The disclosure is also directed to methods of detecting and analyzing methylation patterns in cell-free DNA from organ transplant patients to identify the presence of pathogens as well as quantify contributing tissue proportions as a measurement of the host response.
    Type: Application
    Filed: August 30, 2023
    Publication date: January 25, 2024
    Applicant: CORNELL UNIVERSITY
    Inventors: Iwijn DE VLAMINCK, John Richard LEE, Philip Smith BURNHAM, Alexandre Pellan CHENG, Manikkam SUTHANTHRIAN, Darshana M. DADHANIA
  • Methods of detecting cell-free DNA in biological samples
    Patent number: 11781188
    Abstract: The present disclosure is directed to methods of detecting cell-free DNA (cfDNA) in biological samples and using it to quantify organ damage and identify pathogens. In some aspects, the biological samples are from patients who have undergone solid-organ transplantation. The disclosure is also directed to methods of detecting and analyzing methylation patterns in cell-free DNA from organ transplant patients to identify the presence of pathogens as well as quantify contributing tissue proportions as a measurement of the host response.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: October 10, 2023
    Assignee: CORNELL UNIVERSITY
    Inventors: Iwijn De Vlaminck, John Richard Lee, Philip Smith Burnham, Alexandre Pellan Cheng, Manikkam Suthanthrian, Darshana Dadhania
  • METHODS OF DETECTING CELL-FREE DNA IN BIOLOGICAL SAMPLES
    Publication number: 20200048713
    Abstract: The present disclosure is directed to methods of detecting cell-free DNA (cfDNA) in biological samples and using it to quantify organ damage and identify pathogens. In some aspects, the biological samples are from patients who have undergone solid-organ transplantation. The disclosure is also directed to methods of detecting and analyzing methylation patterns in cell-free DNA from organ transplant patients to identify the presence of pathogens as well as quantify contributing tissue proportions as a measurement of the host response.
    Type: Application
    Filed: April 5, 2018
    Publication date: February 13, 2020
    Applicant: CORNELL UNIVERSITY
    Inventors: Iwijn DE VLAMINCK, John Richard LEE, Philip Smith BURNHAM, Alexandre Pellan CHENG, Manikkam SUTHANTHRIAN, Darshana DADHANIA