Abstract: The present invention provides a method of identifying an animal for which antibiotic treatment, anti-infective treatment, probiotic treatment, immunostimulant treatment, additional monitoring and/or a separate or alternative management strategy is appropriate, comprising: a) collecting a sample from said animal; b) performing a leukocyte differential cell count on said sample; c) comparing said leukocyte differential cell count of (b) with an index of infection; and d) initiating antibiotic treatment, anti-infective treatment, probiotic treatment, immunostimulant treatment, additional monitoring and/or a separate or alternative management strategy of said animal on the basis of said comparing step.

Abstract: An apparatus useful for the rapid collection of blood from a subject (e.g., a blood vessel, such as the vein, artery or capillary bed of a bovine subject) and dispensing the blood therefrom into a test or collection device. In general, the apparatus comprises: (a) a body having a chamber formed therein, said chamber having an inlet and outlet, with said chamber configured to draw blood therein; (b) a hollow barrel connected to said chamber outlet; (c) an ejector operatively associated with said barrel; (d) a hollow needle connected to said body, with said hollow needle in fluid communication with said chamber through said inlet, so that blood can be rapidly drawn into said chamber through said needle. The needle is optionally removed and blood dispensed from the body into a test or collection device by actuating the ejector.

Abstract: The present invention provides methods and compositions for detecting Mycoplasma exposure in a subject.

Abstract: An apparatus useful for the rapid collection of blood from a subject (e.g., a blood vessel, such as the vein, artery or capillary bed of a bovine subject) and dispensing the blood therefrom into a test or collection device. In general, the apparatus comprises: (a) a body having a chamber formed therein, said chamber having an inlet and outlet, with said chamber configured to draw blood therein; (b) a hollow barrel connected to said chamber outlet; (c) an ejector operatively associated with said barrel; (d) a hollow needle connected to said body, with said hollow needle in fluid communication with said chamber through said inlet, so that blood can be rapidly drawn into said chamber through said needle. The needle is optionally removed and blood dispensed from the body into a test or collection device by actuating the ejector.

Abstract: An apparatus useful for the rapid collection of blood from a subject (e.g., the vein of a bovine subject) and dispensing the blood therefrom into a collection device includes: (a) a capillary body having a capillary chamber formed therein, with the chamber having an inlet and outlet, and with said chamber configured to draw blood therein through the inlet by capillary action; (b) a hollow barrel connected to the chamber outlet; (c) a plunger positioned in the barrel; and (d) a hollow needle connected to the capillary body, with the hollow needle in fluid communication with the capillary chamber through the capillary inlet, so that blood can be rapidly drawn into the capillary chamber through the needle by the combined action of vein pressure (or other pressure, if present, such as arterial pressure) and capillary action.

Abstract: The present invention provides a method of identifying an animal for which antibiotic treatment, anti-infective treatment, probiotic treatment, immunostimulant treatment, additional monitoring and/or a separate or alternative management strategy is appropriate, comprising: a) collecting a sample from said animal; b) performing a leukocyte differential cell count on said sample; c) comparing said leukocyte differential cell count of (b) with an index of infection; and d) initiating antibiotic treatment, anti-infective treatment, probiotic treatment, immunostimulant treatment, additional monitoring and/or a separate or alternative management strategy of said animal on the basis of said comparing step.

Abstract: The present invention provides methods and compositions for detecting Mycoplasma exposure in a subject.

Abstract: An apparatus for dispensing solid articles includes a housing and a gate system. The housing defines a dispensing channel and a portal through which articles can flow along a dispensing pathway. The gate system includes a gate member positioned in the dispensing pathway. The gate member is selectively positionable between an open position and a closed position. When the gate member is in the open position, the gate member permits the articles to pass through the portal and, when the gate member is in the closed position, the gate member blocks the articles from passing through the portal. The gate system is configured such that the gate member is passively transitionable between the open and closed positions.

Abstract: An apparatus for dispensing solid articles includes a housing and a gate system. The housing defines a dispensing channel and a portal through which articles can flow along a dispensing pathway. The gate system includes a gate member positioned in the dispensing pathway. The gate member is selectively positionable between an open position and a closed position. When the gate member is in the open position, the gate member permits the articles to pass through the portal and, when the gate member is in the closed position, the gate member blocks the articles from passing through the portal. The gate system is configured such that the gate member is passively transitionable between the open and closed positions.

Abstract: An apparatus for dispensing solid articles includes a housing and a gate system. The housing defines a dispensing channel and a portal through which articles can flow along a dispensing pathway. The gate system includes a gate member positioned in the dispensing pathway. The gate member is selectively positionable between an open position and a closed position. When the gate member is in the open position, the gate member permits the articles to pass through the portal and, when the gate member is in the closed position, the gate member blocks the articles from passing through the portal. The gate system is configured such that the gate member is passively transitionable between the open and closed positions.

Abstract: A method for securing a closure on a cylindrical container (such as a pharmaceutical vial) includes: positioning a closure in a first position, the closure being substantially centered via a centering assembly along an axis that is generally normal to the closure; translating the substantially centered closure along the axis to a second position; positioning a cylindrical container, the container being substantially centered via the centering assembly along the axis; translating the substantially centered closure along the axis to a third position in which it is adjacent the substantially centered container; and relatively rotating the closure and the container to secure the closure to the container. With such a method, both the closure and the cylinder can be centered along the axis, thereby registering them with each other for reliable securing.

Abstract: An apparatus for securing a cap onto a cylindrical container includes a main stage and three clamps. Each of the clamps is pivotally attached to the main stage and rotatable about a respective axis of rotation. The axes of rotation of the clamps define an outer circle having a center. Each of the clamps comprises a generally planar body and an arcuate edge and can be used to both center a cap and grip and rotate a vial for attachment of the cap.

Abstract: An apparatus for securing a cap onto a cylindrical container includes a main stage and three clamps. Each of the clamps is pivotally attached to the main stage and rotatable about a respective axis of rotation. The axes of rotation of the clamps define an outer circle having a center. Each of the clamps comprises a generally planar body and an arcuate edge and can be used to both center a cap and grip and rotate a vial for attachment of the cap.

Abstract: A method for securing a closure on a cylindrical container (such as a pharmaceutical vial) includes: positioning a closure in a first position, the closure being substantially centered via a centering assembly along an axis that is generally normal to the closure; translating the substantially centered closure along the axis to a second position; positioning a cylindrical container, the container being substantially centered via the centering assembly along the axis; translating the substantially centered closure along the axis to a third position in which it is adjacent the substantially centered container; and relatively rotating the closure and the container to secure the closure to the container. With such a method, both the closure and the cylinder can be centered along the axis, thereby registering them with each other for reliable securing.

Abstract: A method of verifying the seating and securing of a closure on a container includes the steps of: (a) positioning a container on a stage of an automated capping station; (b) bringing a closure into contact with the container; (c) detecting the nature of a physical relationship between the container and the closure; (d) responsive to step (c), relatively moving the closure and the container if step (c) indicates seating of the closure on the container is proper; and (e) detecting the nature of a physical relationship between the closure and the container to determine whether the closure is properly secured.

Abstract: An apparatus for facilitating the securing of a cap onto a cylindrical container includes a base and a plurality of blades, each of the blades including a sharp edge and being mounted to the base such that the sharp edge is exposed. The blades are mounted in a generally circular arrangement, with the sharp edges generally radiating from a central portion of the base, such that the sharp edges are positioned to engage a circumferential edge of a cap as it is being secured to the cylindrical container. In this configuration, the apparatus can firmly hold the cap as the cylindrical container (such as a pharmaceutical vial) is rotated to secure the cap onto the container.

Abstract: An apparatus for facilitating the securing of a cap onto a cylindrical container includes a base and a plurality of blades, each of the blades including a sharp edge and being mounted to the base such that the sharp edge is exposed. The blades are mounted in a generally circular arrangement, with the sharp edges generally radiating from a central portion of the base, such that the sharp edges are positioned to engage a circumferential edge of a cap as it is being secured to the cylindrical container. In this configuration, the apparatus can firmly hold the cap as the cylindrical container (such as a pharmaceutical vial) is rotated to secure the cap onto the container.

Abstract: A method for securing a closure on a cylindrical container (such as a pharmaceutical vial) includes: positioning a closure in a first position, the closure being substantially centered via a centering assembly along an axis that is generally normal to the closure; translating the substantially centered closure along the axis to a second position; positioning a cylindrical container, the container being substantially centered via the centering assembly along the axis; translating the substantially centered closure along the axis to a third position in which it is adjacent the substantially centered container; and relatively rotating the closure and the container to secure the closure to the container. With such a method, both the closure and the cylinder can be centered along the axis, thereby registering them with each other for reliable securing.

Abstract: An apparatus for dispensing solid articles includes a housing and a gate system. The housing defines a dispensing channel and a portal through which articles can flow along a dispensing pathway. The gate system includes a gate member positioned in the dispensing pathway. The gate member is selectively positionable between an open position and a closed position. When the gate member is in the open position, the gate member permits the articles to pass through the portal and, when the gate member is in the closed position, the gate member blocks the articles from passing through the portal. The gate system is configured such that the gate member is passively transitionable between the open and closed positions.

Abstract: A method for securing a closure on a cylindrical container (such as a pharmaceutical vial) includes: positioning a closure in a first position, the closure being substantially centered via a centering assembly along an axis that is generally normal to the closure; translating the substantially centered closure along the axis to a second position; positioning a cylindrical container, the container being substantially centered via the centering assembly along the axis; translating the substantially centered closure along the axis to a third position in which it is adjacent the substantially centered container; and relatively rotating the closure and the container to secure the closure to the container. With such a method, both the closure and the cylinder can be centered along the axis, thereby registering them with each other for reliable securing.