Abstract: The present invention relates to methods for the treatment of a bone fracture or bone defect. The invention discloses the effective use of an anti-gremlin-1 antibody to accelerate the healing and bridging of bone tissue in segmental gap defects; and demonstrates that inhibitors of gremlin-1 activity may provide improved therapies for treating or preventing fracture non-union.

Abstract: The apparatus has a tube having an exterior tube surface, the exterior tube surface defining one or more grooves. The apparatus further has a portion occupying each of the one or more grooves and integrally formed with the tube. The portion is adapted to reflect light in the visible spectrum. The tube and the portion together define a guy guard. A method and system for forming the apparatus are also disclosed.

Abstract: A closure assembly to be installed in an opening for a building, said closure assembly comprising a frame for supporting a moveable closure member therewithin, said frame including top, bottom and side members, one of the members including a hollow pocket within the interior of said member and for receiving a spring biased roller assembly upon which a flexible material is accumulated, said flexible material being selected from a blind, a bug screen, a solar screen, or the like, the flexible material being movable between a fully retracted first position whereat the material is contained within the pocket to a fully extended second position whereat the material covers some or all of the opening of the building.

Abstract: An actuator for a latch assembly comprising a cam member including cam surfaces to engage detents to, operate said latch assembly, the resulting motion of the detents to operate a release member for a header latching portion and simultaneously to operate a release member for a sill latching portion, or alternatively to operate release members for jamb latching portions.

Abstract: A guy guard assembly for use with a guy wire is disclosed. The assembly comprises a tubular guy guard and a clamp. The tube wall has an aperture. The clamp includes a bolt, a first plastic portion and a second plastic portion. The bolt has a head outside the tube and a threaded shaft extending from the head through the aperture. The first portion is inside the tube against the tube wall; has the bolt extending therethrough; and defines a first jaw. The second portion defines a second jaw and is threaded to the bolt. The portions have a first configuration, wherein the jaws are relatively distal to and spaced from one another to define a slot for said wire and, from the first configuration, are configurable by rotating the bolt to a second configuration, wherein the jaws are relatively proximal to one another to grip said wire.

Abstract: An actuator for a latch assembly comprising a cam member including cam surfaces to engage detents to, operate said latch assembly, the resulting motion of the detents to operate a release member for a header latching portion and simultaneously to operate a release member for a sill latching portion, or alternatively to operate release members for jamb latching portions.

Abstract: A reinforcing block for a closure tilt latch, comprising a body fastened in a closure track fastened to a frame, said body having a top and bottom and having a locking detent extending therein said locking detent providing a vertical face extending toward said top of said body from intermediate said top and bottom, the tilt latch being compatible with the vertical face of said locking detent, wherein when said latch engages said detent said block provides a reinforcement path to the closure frame to strengthen the loading capability of said closure and to reduce the risk of the latch from disengaging said track under loading which track would be subject to distortion had the block not been utilized.

Abstract: A retractable screen is located within a frame portion of a window. The screen accumulates on and pays out from a spring biased roller located in said frame portion. The screen is fully retractable and for the most part hidden for viewing, egress or cleaning purposes, and is available as desired when moved to the operable position. The screening material utilized includes “T” shaped members for easy installation in compatible grooves provided with the handle and the roller.

Abstract: A roll screen cassette is provided for installation in a closure assembly which has a frame for moveably retaining a closure member. The frame includes a header, sill, and vertical jamb sections. At least one of the sections includes a pocket formed within its interior. The pocket having a first predetermined configuration defined by the interior of the section and for receipt of the roll screen. The roll screen including a pair of brackets from which said roll screen is pivotally supported. The pair of brackets having a second predetermined configuration compatible with the pocket of the frame section having the first predetermined configuration. The pair of brackets utilized for removeably retaining the roll screen within the pocket in use.

Abstract: This invention relates to a retractable screen system for a closure assembly and improvements thereof which allows the secure sliding and subsequent retraction of the screen from a operative position to a retracted position. The invention is preferably embodied in a window assembly but finds application also in large pivoting windows and patio doors.

Abstract: A roll screen cassette for installation in a closure assembly having a frame for moveably retaining a closure member, said frame including a header, sill, and vertical jamb sections, at least one of said sections including a pocket formed within the interior thereof, said pocket having a first predetermined configuration defined by the interior of the section and for receipt of the roll screen, said roll screen comprising a pair of brackets from which said roll screen is pivotally supported, said pair of brackets having a second predetermined configuration compatible with said pocket of said frame section having the first predetermined configuration, said pair of brackets utilized for removeably retaining the roll screen within said pocket in use, said pair of brackets and roll screen being removeably held in position with respect to said frame only by said pocket having the first predetermined configuration and said pair of brackets having a second predetermined configuration compatible with said pocket and

Abstract: A roll screen cassette for installation in a closure assembly having a frame for moveably retaining a closure member, the frame including a header, sill, and vertical jamb sections, at least one of the sections including a pocket formed within the interior thereof, the pocket having a first predetermined configuration defined by the interior of the section and for receipt of the roll screen, the roll screen comprising a pair of brackets from which the roll screen is pivotally supported, the pair of brackets having a second predetermined configuration compatible with the pocket of the frame section having the first predetermined configuration, the pair of brackets utilized for removeably retaining the roll screen within the pocket in use, the pair of brackets and roll screen being removeably held in position with respect to said frame only by the pocket having the first predetermined configuration and the pair of brackets having a second predetermined configuration compatible with the pocket and being located

Abstract: A continuous roll of screen which may be payed out from said roll by an installer or manufacturer to a required predetermined window size, or alternatively patio door size, said screen comprising a free end which allows the installer to pay the screen off of the roll upon which the screen is accumulated course upon course, one end of said screen being disposed at the end of the courses accumulated on the roll from which the screening is payed off and the other end being a free end, said screen having side edges and preferably being manufactured from preferably vinyl-coated fiberglass, the edges of said screen having affixed thereto a generally preferably T-shaped key manufactured from a flexible material, for example polyvinyl chloride, which is affixed preferably by radio frequency welding (or RF welding) with the edges and preferably each of the edges, and in one embodiment at least one edge of said screen, wherein the vinyl coating provided on the screen melds with the polyvinyl chloride key to form a resi

Abstract: A continuous roll of screen which may be payed out from said roll by an installer or manufacturer to a required predetermined window size, or alternatively patio door size, said screen comprising a free end which allows the installer to pay the screen off of the roll upon which the screen is accumulated course upon course, one end of said screen being disposed at the end of the courses accumulated on the roll from which the screening is payed off and the other end being a free end, said screen having side edges and preferably being manufactured from preferably vinyl-coated fiberglass, the edges of said screen having affixed thereto a generally preferably T-shaped key manufactured from a flexible material, for example polyvinyl chloride, which is affixed preferably by radio frequency welding (or RF welding) with the edges and preferably each of the edges, and in one embodiment at least one edge of said screen, wherein the vinyl coating provided on the screen melds with the polyvinyl chloride key to form a resi

Abstract: A flap valve vent hood for discharging air to atmosphere from clothes dryers and bathroom vents is provided freeze-free by a secondary valve that is mounted on the principal flap valve and covering an open area that provides a secondary air flow path through the principal flap valve. The principal flap valve and the secondary valve are normally closed and the principal flap valve is biased to its closed position by gravity. A lip along an edge of the open area may be provided to minimize accumulation of moisture where the two valves are in contact with one another. A soffit vent hood of particular construction is provided in which there are two members detachably interconnected one being a downwardly directed hood and the other an insert therefor which carries the valves for respective ones of a pair of outlet discharge openings.