Patents by Inventor John Robert Rizzo

John Robert Rizzo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiazolyl-pyrazolopyrimidine compounds as synthetic intermediates and related synthetic processes
    Patent number: 8563718
    Abstract: The present invention relates to a synthetic intermediate of the formula: and its use in a synthetic process to make compounds of the formula
    Type: Grant
    Filed: September 29, 2009
    Date of Patent: October 22, 2013
    Assignee: Eli Lilly and Company
    Inventors: John Robert Rizzo, Sathish Kumar Boini, Radhe Krishan Vaid
  • Inhibitors of diacylglycerol acyltransferase
    Patent number: 8299061
    Abstract: This invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof; as well as a method for treating obesity, a method for treating diabetes, and a pharmaceutical composition.
    Type: Grant
    Filed: December 7, 2010
    Date of Patent: October 30, 2012
    Assignee: Eli Lilly and Company
    Inventors: Macklin Brian Arnold, Thomas James Beauchamp, Emily Jane Canada, Erik James Hembre, Jianliang Lu, John Robert Rizzo, John Mehnert Schaus, Qing Shi
  • THIAZOLYL-PYRAZOLOPYRIMIDINE COMPOUNDS AS SYNTHETIC INTERMEDIATES AND RELATED SYNTHETIC PROCESSES
    Publication number: 20110166345
    Abstract: The present invention relates to a synthetic intermediate of the formula: and its use in a synthetic process to make compounds of the formula
    Type: Application
    Filed: September 29, 2009
    Publication date: July 7, 2011
    Applicant: ELI LILLY AND COMPANY
    Inventors: John Robert Rizzo, Sathish Kumar Boini, Radhe Krishan Vaid
  • Inhibitors of Diacylglycerol Acyltransferase
    Publication number: 20110144091
    Abstract: This invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof; as well as a method for treating obesity, a method for treating diabetes, and a pharmaceutical composition.
    Type: Application
    Filed: December 7, 2010
    Publication date: June 16, 2011
    Applicant: ELI LILLY AND COMPANY
    Inventors: Macklin Brian Arnold, Thomas James Beauchamp, Emily Jane Canada, Erik James Hembre, Jianliang Lu, John Robert Rizzo, John Mehnert Schaus, Qing Shi
  • Methods of using novel compounds as neuro-protective agents
    Patent number: 6579871
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: June 17, 2003
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie
  • Preparation of substituted piperidin-4-ones
    Patent number: 6538136
    Abstract: The present invention provides a novel process for the preparation of substituted piperidine-4-ones useful as intermediates in the preparation of pharmaceuticals.
    Type: Grant
    Filed: December 11, 2001
    Date of Patent: March 25, 2003
    Assignee: Eli Lilly and Company
    Inventors: John Robert Rizzo, Michael Alexander Staszak, Tony Yantao Zhang
  • Methods of using novel compounds as neuro-protective agents
    Publication number: 20030050311
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Application
    Filed: September 3, 2002
    Publication date: March 13, 2003
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, David Lee Varie
  • Novel compounds useful as neuro-protective agents
    Publication number: 20020177595
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Application
    Filed: March 27, 2002
    Publication date: November 28, 2002
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, David Lee Varie
  • Methods of using compounds as neuro-protective agents
    Patent number: 6472387
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: October 29, 2002
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie
  • Compounds useful as neuro-protective agents
    Patent number: 6448396
    Abstract: The present invention provides a process of preparing a compound of the formula IV wherein: R1 and R2 are each individually -(C1-C6)alkyl, -(C1-C6)alkoxy or phenyl, R3 is H or -(C1-C6)alkyl, R6 is —NR7R8, morpholin-1-yl, imidazol-1-yl, 4,5-dihydro-1H-imidazol-2-yl, thiomorpholin-1-yl, piperazin-1-yl or piperazin-1-yl substituted with -(C1-C4)alkyl or  and R7 and R8 are each individually hydrogen, -(C1-C6)alkyl, —(CH2)pOH,  —(CH2)p-piperidyl, —(CH2)pS(C1-C6)alkyl, —(CH2)pO(C1-C6)alkyl  where R9 is (C1-C6)alkyl; P is an integer from 1-3 both inclusive; q is 0 or 1; and t is 1 to 6 both inclusive; or a pharmaceutically acceptable salt, hydrate or optical isomer thereof, which is useful as a neuroprotective agent.
    Type: Grant
    Filed: September 23, 1998
    Date of Patent: September 10, 2002
    Assignee: Eli Lilly and Company
    Inventors: Benjamin Alan Anderson, Lawrence Joseph Heinz, Jill Ann Panetta, Michael LeRoy Phillips, John Allan Rieck, III, John Robert Rizzo, John Kevin Shadle, David Lee Varie
  • Methods of using novel compounds as neuro-protective agents
    Patent number: 6423709
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: November 28, 2001
    Date of Patent: July 23, 2002
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie
  • METHODS OF USING NOVEL COMPOUNDS AS NEURO-PROTECTIVE AGENTS
    Publication number: 20020065274
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Application
    Filed: November 28, 2001
    Publication date: May 30, 2002
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck,, David Lee Varie
  • Compounds useful as neuro-protective agents
    Patent number: 6380213
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: November 17, 2000
    Date of Patent: April 30, 2002
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie
  • NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS
    Publication number: 20010027194
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Application
    Filed: September 23, 1998
    Publication date: October 4, 2001
    Inventors: BENJAMIN ALAN ANDERSON, LAWRENCE JOSEPH HEINZ, JILL ANN PANETTA, MICHAEL LEROY PHILLIPS, JOHN ALLAN RIECK, JOHN ROBERT RIZZO, JOHN KEVIN SHADLE, DAVID LEE VARIE
  • Compounds useful as neuro-protective agents
    Patent number: 6166216
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: August 4, 1999
    Date of Patent: December 26, 2000
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie
  • Compounds useful as neuro-protective agents
    Patent number: 6156748
    Abstract: This invention relates to novel phenyl oxazoles, thiazoles, oxazolines, oxadiazoles and benzoxazoles useful as neuro-protective agents.
    Type: Grant
    Filed: October 6, 1997
    Date of Patent: December 5, 2000
    Assignee: Eli Lilly and Company
    Inventors: Jill Ann Panetta, John Kevin Shadle, Lawrence Joseph Heinz, Michael LeRoy Phillips, John Robert Rizzo, Benjamin Alan Anderson, John Allan Rieck, III, David Lee Varie