Patents by Inventor John Romer

John Romer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Suppression of inhibitors
    Publication number: 20010034327
    Abstract: The present invention relates to methods for inhibiting malignant tumour growth, invasion and/or metastasis in a patient, the method comprising suppressing the inhibitory activity of an inhibitor of a protease or of a non-proteolytic matrix-degrading enzyme (IPNME) in malignant tumour tissue or potential malignant tumour tissue. The suppression may be brought about by administering compounds interacting with the IPNME, but also administration of compounds interacting with transcription of genes encoding the IPNME is a possibility. The invention also relates to methods of selecting and identifying compounds in the therapeutical methods, as well of the use of such compounds in the treatment of malignancies.
    Type: Application
    Filed: April 18, 2001
    Publication date: October 25, 2001
    Inventors: Niels Brunner, John Romer, Vincent Ellis, Charles Pyke, Jan Grondahl-Hansen, Helle Pedersen Pappot, Heine Hoi Hansen, Keld Dano
  • Suppression of inhibitors
    Patent number: 6224865
    Abstract: The present invention relates to methods for inhibiting malignant tumour growth, invasion and/or metastasis in a patient, the method comprising suppressing the inhibitory activity of an inhibitor of a protease or of a non-proteolytic matrix-degrading enzyme (IPNME) in malignant tumour tissue or potential malignant tumour tissue. The suppression may be brought about by administering compounds interacting with the IPNME, but also administration of compounds interacting with transcription of genes encoding the IPNME is a possibility. The invention also relates to methods of selecting and identifying compounds in the therapeutical methods, as well of the use of such compounds in the treatment of malignancies.
    Type: Grant
    Filed: May 15, 1996
    Date of Patent: May 1, 2001
    Assignee: Cancerforskningsfonden AF 1989
    Inventors: Nils Brünner, John Rømer, Vincent Ellis, Charles Pyke, Jan Grøndahl-Hansen, Helle Pedersen, Heine Høi Hansen, Keld Danø
  • 2-Phenyl-3-Azoylbenzothiophene for lowering intraocular pressure
    Patent number: 5798369
    Abstract: The present invention provides a novel use of a compound of formula I ##STR1## or a pharmaceutically and/or physiologically acceptable salt or solvate thereof for the manufacture of a pharmaceutical composition useful for lowering intraocular pressure.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: August 25, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Niels Korsgaard, John Romer