Patents by Inventor John Rose

John Rose has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11000631
    Abstract: Devices, systems, and methods for applying a bioactive coating to an exterior surface of an implant are disclosed. In some embodiments, the bioactive coating may be applied to the surfaces of the implant within the operating room at the time of implantation. In one embodiment, the implant may be a temporary spacer used to temporary replace an implant in a patient suffering from an infection. The temporary spacer being, for example, an antibacterial material for fighting the infection. In some embodiments, the method includes providing a mold of the implant, and providing the bioactive coating within the mold. The method may further include inserting the implant into the mold so that the exterior surface of the implant contacts the bioactive coating, and then removing the implant from the mold.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: May 11, 2021
    Assignee: Smith & Nephew, Inc.
    Inventors: John Rose, Sied William Janna, Alisha Wilson Bergin
  • Patent number: 10853096
    Abstract: Embodiments include a code loader method for loading attributes corresponding to an isolated method by a container-based language runtime. The attributes are received by the container-based language runtime without any specified container for storage of the isolated method attributes. The attributes received as parameters of code loader method and include instructions, live objects, and parameter types corresponding to the isolated method. The container-based language runtime selects a first-order container for storing the attributes of the isolated method.
    Type: Grant
    Filed: May 27, 2020
    Date of Patent: December 1, 2020
    Assignee: Oracle International Corporation
    Inventors: Michael Haupt, John Rose, Brian Goetz
  • Publication number: 20200293335
    Abstract: Embodiments include a code loader method for loading attributes corresponding to an isolated method by a container-based language runtime. The attributes are received by the container-based language runtime without any specified container for storage of the isolated method attributes. The attributes received as parameters of code loader method and include instructions, live objects, and parameter types corresponding to the isolated method. The container-based language runtime selects a first-order container for storing the attributes of the isolated method.
    Type: Application
    Filed: May 27, 2020
    Publication date: September 17, 2020
    Applicant: Oracle International Corporation
    Inventors: Michael Haupt, John Rose, Brian Goetz
  • Publication number: 20200282108
    Abstract: An orthopaedic implant comprising a titanium substrate having silver deposited thereon, wherein the silver is operable to be eluted at a rate of at least 0.25 ?g/cm2 24h-1, for at least 14 consecutive days, in use. The invention also extends to a method of producing an orthopaedic implant and use of the same.
    Type: Application
    Filed: January 25, 2017
    Publication date: September 10, 2020
    Inventors: Darren Wilson, John Rose, Nathaniel Kelley Grusin
  • Patent number: 10719337
    Abstract: Embodiments include a code loader method for loading attributes corresponding to an isolated method by a container-based language runtime. The attributes are received by the container-based language runtime without any specified container for storage of the isolated method attributes. The attributes received as parameters of code loader method and include instructions, live objects, and parameter types corresponding to the isolated method. The container-based language runtime selects a first-order container for storing the attributes of the isolated method.
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: July 21, 2020
    Assignee: Oracle International Corporation
    Inventors: Michael Haupt, John Rose, Brian Goetz
  • Patent number: 10606614
    Abstract: Embodiments include a code loader method for loading attributes corresponding to an isolated method by a container-based language runtime. The attributes are received by the container-based language runtime without any specified container for storage of the isolated method attributes. The attributes received as parameters of code loader method and include instructions, live objects, and parameter types corresponding to the isolated method. The container-based language runtime selects a first-order container for storing the attributes of the isolated method.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: March 31, 2020
    Assignee: Oracle International Corporation
    Inventors: Michael Haupt, John Rose, Brian Goetz
  • Publication number: 20200000977
    Abstract: A method of incorporating silver and/or copper into a biomedical implant includes: providing an implant having an outer surface; depositing silver and/or copper onto the outer surface of the implant; diffusing the silver and/or copper into a subsurface zone adjacent the outer surface; and oxidizing or anodizing the implant after the diffusion step to form an oxidized or anodized layer that contains at least some amount of elemental silver, elemental copper or silver or copper ions or compounds.
    Type: Application
    Filed: August 20, 2019
    Publication date: January 2, 2020
    Inventors: Vivek D. Pawar, John Rose, Carolyn Weaver
  • Patent number: 10435712
    Abstract: The present invention relates to the discovery of a high titer hybrid-virus vector that gives rise to high titer virus like vesicles (VLVs) that can be used as a vaccine. The invention includes compositions and methods of generating an evolved hybrid-virus vector vaccine and selecting high titer VLVs, methods of treating and/or preventing or immunizing against, a specific disease or disorder, and methods of inducing a memory T cell and B cell immune response in a subject administered the VLV composition produced thereby. Furthermore, the invention encompasses a pharmaceutical composition for vaccinating a subject as well as a high titer protein expression system.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: October 8, 2019
    Assignee: Yale University
    Inventors: John Rose, Nina Rose
  • Publication number: 20190282279
    Abstract: A multi-layer, fiber-reinforced composite orthopaedic fixation device having a design selected based on a desired characteristic of the orthopaedic fixation device. The design may be selected according to a model of the device, the model defining design constraints, and the design may comprise a pattern of the fiber angle for each layer. The selection of a design may be analyzed using finite element analysis to determine whether the design will comprise the desired characteristic.
    Type: Application
    Filed: June 7, 2019
    Publication date: September 19, 2019
    Inventors: James K. Rains, Gene Edward Austin, John Rose, Joseph Michael Ferrante, Darin S. Gerlach, Nathaniel Kelley Grusin, Sied W. Janna, Henry B. Faber, Mark S. Gosney, Darren James Wilson
  • Patent number: 10413640
    Abstract: A method of incorporating silver and/or copper into a biomedical implant includes: providing an implant having an outer surface; depositing silver and/or copper onto the outer surface of the implant; diffusing the silver and/or copper into a subsurface zone adjacent the outer surface; and oxidizing or anodizing the implant after the diffusion step to form an oxidized or anodized layer that contains at least some amount of elemental silver, elemental copper or silver or copper ions or compounds.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: September 17, 2019
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Vivek D. Pawar, John Rose, Carolyn Weaver
  • Patent number: 10357292
    Abstract: A multi-layer, fiber-reinforced composite orthopedic fixation device having a design selected based on a desired characteristic of the orthopedic fixation device. The design may be selected according to a model of the device, the model defining design constraints, and the design may comprise a pattern of the fiber angle for each layer. The selection of a design may be analyzed using finite element analysis to determine whether the design will comprise the desired characteristic.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: July 23, 2019
    Assignee: Smith & Nephew, Inc.
    Inventors: James K. Rains, Gene Edward Austin, John Rose, Joseph Michael Ferrante, Darin S. Gerlach, Nathaniel Kelley Grusin, Sied W. Janna, Henry B. Faber, Mark S. Gosney, Darren James Wilson
  • Publication number: 20190138319
    Abstract: Embodiments include a code loader method for loading attributes corresponding to an isolated method by a container-based language runtime. The attributes are received by the container-based language runtime without any specified container for storage of the isolated method attributes. The attributes received as parameters of code loader method and include instructions, live objects, and parameter types corresponding to the isolated method. The container-based language runtime selects a first-order container for storing the attributes of the isolated method.
    Type: Application
    Filed: January 7, 2019
    Publication date: May 9, 2019
    Applicant: Oracle International Corporation
    Inventors: Michael Haupt, John Rose, Brian Goetz
  • Patent number: 10175998
    Abstract: Embodiments include a code loader method for loading attributes corresponding to an isolated method by a container-based language runtime. The attributes are received by the container-based language runtime without any specified container for storage of the isolated method attributes. The attributes received as parameters of code loader method and include instructions, live objects, and parameter types corresponding to the isolated method. The container-based language runtime selects a first-order container for storing the attributes of the isolated method.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: January 8, 2019
    Assignee: Oracle International Corporation
    Inventors: Michael Haupt, John Rose, Brian Goetz
  • Publication number: 20180333588
    Abstract: In some embodiments, an apparatus includes a catheter having a catheter body, a light emitter disposed at a distal end of the catheter body, and a fluid conduit coupleable to a source of fluid. The fluid conduit configured to discharge fluid from the source via the conduit and out a distal end of the catheter body. A spacing member is disposed at the distal end of the catheter body and can be moved between a collapsed configuration and an expanded configuration. In the expanded configuration, the spacing member is disposed about the light emitter. The spacing member is at least partially transmissive and/or transflective of light emitted from the light emitter. The apparatus configured to be inserted at least partially into a body lumen, to discharge fluid into the body lumen, and to emit light from the light emitter to illuminate an interior wall of the body lumen.
    Type: Application
    Filed: May 10, 2018
    Publication date: November 22, 2018
    Applicant: Illumnation Corp.
    Inventors: Baruch B. LIEBER, John A. ROSE
  • Patent number: 9987353
    Abstract: The present invention relates to the discovery of compositions and methods for therapeutic immunization for treatment of chronic hepatitis B. Methods of the invention include a method generating an evolved high titer hybrid-hepatitis B virus (HBV) vector, methods of treating and/or preventing HBV, and methods of inducing a memory T and B cell immune response against HBV infection in a subject administered the VLV composition produced thereby. Furthermore, the invention encompasses a pharmaceutical composition for vaccinating a subject to protect the subject against infection with HBV.
    Type: Grant
    Filed: May 11, 2015
    Date of Patent: June 5, 2018
    Assignee: Yale University
    Inventors: Michael Robek, John Rose, Tracy Reynolds
  • Patent number: 9992064
    Abstract: The following description is directed to configuring network devices. In one example, at a network device deployment pipeline, a request can be received from a non-integrated configuration tool to configure a network device of a network. The configuration of the network device can be scheduled so that both an integrated configuration tool of the network device deployment pipeline and the non-integrated configuration tool can configure the network.
    Type: Grant
    Filed: April 10, 2015
    Date of Patent: June 5, 2018
    Assignee: Amazon Technologies, Inc.
    Inventors: Rachit Chawla, Christopher John Rose, Jeremy Ryan Volkman, Mayilan Balachandran, Christopher Edward Folger, Kenneth Oliver Henderson, Jr., Dmytro Taran, Abhoy Bhaktwatsalam, Justin Oliver Pietsch
  • Patent number: 9893940
    Abstract: The following description is directed to topologically aware network device configuration. In one example, components to be configured within a network can be mapped to one or more redundancy groups within a network topology of the network. The components to be configured can be selectively configured within the network so that network traffic continues during the configuration. Selectively configuring the components can include choosing an order to configure the components based on configuration rules and the mapping of the components to the one or more redundancy groups.
    Type: Grant
    Filed: May 26, 2015
    Date of Patent: February 13, 2018
    Assignee: Amazon Technologies, Inc.
    Inventors: Rachit Chawla, Mayilan Balachandran, Jeremy Ryan Volkman, Christopher John Rose, Kenneth Oliver Henderson, Jr., Muralidhar Koka, Abhoy Bhaktwatsalam
  • Publication number: 20180032355
    Abstract: Embodiments include a code loader method for loading attributes corresponding to an isolated method by a container-based language runtime. The attributes are received by the container-based language runtime without any specified container for storage of the isolated method attributes. The attributes received as parameters of code loader method and include instructions, live objects, and parameter types corresponding to the isolated method. The container-based language runtime selects a first-order container for storing the attributes of the isolated method.
    Type: Application
    Filed: July 31, 2017
    Publication date: February 1, 2018
    Applicant: Oracle International Corporation
    Inventors: Michael Haupt, John Rose, Brian Goetz
  • Publication number: 20180032347
    Abstract: Embodiments include a code loader method for loading attributes corresponding to an isolated method by a container-based language runtime. The attributes are received by the container-based language runtime without any specified container for storage of the isolated method attributes. The attributes received as parameters of code loader method and include instructions, live objects, and parameter types corresponding to the isolated method. The container-based language runtime selects a first-order container for storing the attributes of the isolated method.
    Type: Application
    Filed: July 31, 2017
    Publication date: February 1, 2018
    Applicant: Oracle International Corporation
    Inventors: Michael Haupt, John Rose, Brian Goetz
  • Publication number: 20180012509
    Abstract: An apparatus comprises training means to provide training with respect to behavior modification, stimulus means to provide an association with the training means, and stimulus generating means to generate a stimulus post presentation of the training means. The stimulus generating means has a plurality of potential different stimuli types with at least two stimuli in time-spaced-apart relationship to each other to create a distinct trigger as a stimulus phrase for an individual to recall the training or therapy. The stimulus generating means makes available a number of stimulus phrases to an individual user for different environments expected by an individual user so one stimulus phrase is adopted by an individual user as their distinct trigger in an environment expected by the user. The stimulus means is arranged to provide at least a part of the distinct trigger during association with the training sufficient for recall of the training or therapy.
    Type: Application
    Filed: July 5, 2017
    Publication date: January 11, 2018
    Inventor: John Rose