Abstract: The present invention relates to dihydro-cyclopenta-isoquinoline derivatives of formula (I): processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain autoimmune responses), and in particular, disorders caused by the interaction of IgE with the Fc?RI receptor.

Abstract: The invention relates to compounds of formula (I): and related aspects.

Abstract: The present invention relates to sodium-hydrogen exchanger 3 (NHE3) inhibitor compounds of the Formula: to pharmaceutical compositions comprising the compound and to the use of the compound for the treatment of certain diseases associated with elevated sodium and/or phosphate levels.

Abstract: The invention provides compounds of the formula: (A), pharmaceutically acceptable salts, pharmaceutical compositions thereof and methods of using these compounds, salts, or compositions to treat hyperphosphatemia, chronic kidney disease, and/or the cardiovascular disease associated with chronic kidney disease.

Abstract: The invention provides compounds of the formula: (A), pharmaceutically acceptable salts, pharmaceutical compositions thereof and methods of using these compounds, salts, or compositions to treat hyperphosphatemia, chronic kidney disease, and/or the cardiovascular disease associated with chronic kidney disease.

Abstract: The trailer 10 is a trailer 10 for a folding camper wherein an accommodation space is arranged to be folded out of the trailer 10 at a final destination. The present invention provides a modular hoist 40 which is stored within a hoist storage compartment 50 mounted on the trailer 10. The modular hoist 40 can be mounted to and secured to the trailer 10 and it can then be used to raise and lower the auxiliary equipment to or from upper securement rails 20, 22. In use, a motorbike or other auxiliary equipment is initially secured within a transportation frame 60 on the ground adjacent to the trailer 10. This may comprise locating the wheels of the motorbike in or on a bogey 62 and then securing an upper frame 66 and straps 68 to a lower frame 61. Once secured, attachment means 49 located on the end of a flexible hoist member 48 can be secured to the upper frame 66. Once secured, the modular hoist 40 can then be operated to raise the auxiliary equipment and the transportation frame 60 to the required height.

Abstract: An attachable flame simulating apparatus includes a coupling appendage, having a distal end and a proximal end, a housing adjacent the proximal end of the coupling appendage, the housing comprising one or more light sources, and a projection surface extending from the housing. Furthermore, the distal end of the coupling appendage is removably attachable to a vehicle.

Abstract: A drive axle assembly includes a drive axle configured to rotate with a driving torque, a first clutch pack assembly located at an end of the drive axle, and a second clutch pack assembly located at an opposite end of the drive axle. A first drive wheel assembly is operatively connected to the first clutch pack assembly, wherein the first clutch pack assembly is configured to convert the driving torque of the drive axle to a first driving torque of the first drive wheel. A second drive wheel assembly is operatively connected to the second clutch pack assembly, wherein the second clutch pack assembly is configured to convert the driving torque of the drive axle to a second driving torque of the second drive wheel.

Abstract: A drive axle assembly includes a drive axle configured to rotate with a driving torque, a first clutch pack assembly located at an end of the drive axle, and a second clutch pack assembly located at an opposite end of the drive axle. A first drive wheel assembly is operatively connected to the first clutch pack assembly, wherein the first clutch pack assembly is configured to convert the driving torque of the drive axle to a first driving torque of the first drive wheel. A second drive wheel assembly is operatively connected to the second clutch pack assembly, wherein the second clutch pack assembly is configured to convert the driving torque of the drive axle to a second driving torque of the second drive wheel.

Abstract: A piling protector includes an abrasion resistant surface disposed along an outer surface of the piling protector, a plurality of channels defined in an inner surface of the piling protector, the plurality of channels facilitating flexibility of the piling protector, and first and second appendages extending from first and second lateral sides of the piling protector. The first and second appendages are configured for attachment to a piling. Portions of the interior surface of the piling protector defined between channels of the piling protector are curved to correspond to a curved outer surface of a generally cylindrical piling. The piling protector is configured for engagement with both a curved outer surface of a generally cylindrical pylon and a flat surface.

Abstract: An attachable flame simulating apparatus includes a coupling appendage, having a distal end and a proximal end, a housing adjacent the proximal end of the coupling appendage, the housing comprising one or more light sources, and a projection surface extending from the housing. Furthermore, the distal end of the coupling appendage is removably attachable to a vehicle.

Abstract: Compounds represented by Formula (I): or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, and as cardioprotectants.

Abstract: A drive axle assembly includes a drive axle configured to rotate with a driving torque, a first clutch pack assembly located at an end of the drive axle, and a second clutch pack assembly located at an opposite end of the drive axle. A first drive wheel assembly is operatively connected to the first clutch pack assembly, wherein the first clutch pack assembly is configured to convert the driving torque of the drive axle to a first driving torque of the first drive wheel. A second drive wheel assembly is operatively connected to the second clutch pack assembly, wherein the second clutch pack assembly is configured to convert the driving torque of the drive axle to a second driving torque of the second drive wheel.

Abstract: A system for capturing regenerative energy includes a battery configured to provide power for a traction motor and other operations of a vehicle and a capacitor connected to the battery. An auxiliary motor is configured to operate as a generator during a regenerative energy operation. The system further includes a controller configured to direct the regenerative energy to the capacitor during the regenerative energy operation and discharge the capacitor to provide power to the traction motor or for the other operations of the vehicle.

Abstract: A method for controlling a power-shift transmission comprising controlling a vehicle travel speed by simultaneously slipping two or more clutch packs associated with opposing directions of vehicle travel and adjusting an engine speed, according to a programmed response associated with a change in one or more of the engine speed, a torque converter slip, a selected direction of vehicle travel, and an accelerator position.

Abstract: A window shade having a lift cord that is partially or entirely contained within a tape. Preferably, the tape is made of fabric or cloth. In a first embodiment, the tape portion of the window shade is made of a cloth that is woven to form a tube. The lift cord or cords of any window shade are contained within the hollow portion of the tube. Additionally, the cloth tape is spot stitched to the window shade at a spacing small enough to prevent the entry of a head of a child, person, or pet. As a lowered shade is raised by the lift cord, the lift cord tape tightly gathers so as to prevent the formation of loops, or at least loops large enough to engulf a head.

Abstract: A pressurized medical device comprising an inflatable element arranged to contact a part of a patient; a fluid connector attached to the element and arranged to deliver fluid to the element; a control system arranged to control flow of fluid in the device; a first element pressure sensor arranged to measure the pressure exerted by the element on the part of the patient; and detection means arranged to detect malfunctioning of the first element pressure sensor.

Abstract: Compounds of Formula (I) or pharmaceutically acceptable salts thereof, are inhibitors of glycogen phosphorylase and are useful in the prophylactic or therapeutic treatment of diabetes, hyperglycemia, hypercholesterolemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis or tissue ischemia e.g. myocardial ischemia, or as cardioprotectants or inhibitors of abnormal cell growth.