Patents by Inventor John Russo
John Russo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250140432Abstract: A method of making a radioisotopic power source, including receiving a predetermined amount of a plurality of Metal-Organic Framework (MOF) particles within a reactor vessel, degassing the received predetermined amount of the MOF. The degassing includes placing the predetermined amount of the MOF under vacuum conditions, heating the received predetermined amount of the MOF above a first predetermined temperature for a first predetermined time period, and sealing the heated MOF. The method also includes cooling the heated and sealed predetermined amount of the MOF to a second predetermined temperature, while maintaining a pressure of the reactor vessel to a first predetermined pressure value for a second predetermined time period, receiving a predetermined amount of a plurality of beta emitter particles at a gaseous state and mixing the predetermined amount of beta emitter particles with the cooled predetermined amount of the MOF.Type: ApplicationFiled: October 28, 2023Publication date: May 1, 2025Applicant: Direct Kinetic Solutions IncInventors: Brenda Ann Smith, John Russo, William Ray, II
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Publication number: 20240311527Abstract: A computer-implemented system uses multiscale modeling and optimization algorithms to design DNA nanostructures that self-assemble into a target structure, such as a tetrastack lattice. The system converts a target structure into a Boolean Satisfiability problem and models nanostructure units as “patchy” nanostructure models, where patches encode kinetic properties that affect how each nanostructure model connects with other nanostructure models. The system iteratively simulates self-assembly of a plurality of nanostructure models into a nanostructure assembly model, and compares the nanostructure assembly model with the target structure to determine a set of optimal parameters (such as patch type assignments) for the nanostructure units that reliably result in self-assembly into the target structure.Type: ApplicationFiled: March 15, 2024Publication date: September 19, 2024Inventors: Petr Sulc, Michael Matthies, Flavio Romano, John Russo, Hao Liu
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Publication number: 20230414670Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: ApplicationFiled: September 11, 2023Publication date: December 28, 2023Applicant: MiMedx Group, Inc.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
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Patent number: 11752174Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: GrantFiled: December 14, 2020Date of Patent: September 12, 2023Assignee: MiMedx Group, Inc.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
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Publication number: 20230081282Abstract: A general framework which transforms the inverse problem of self-assembly of colloidal crystals into a Boolean satisfiability problem for which solutions can be found numerically is described herein. Given a reference structure and the desired number of components, our approach produces designs for which the target structure is an energy minimum, and also allows to exclude solutions that correspond to competing structures.Type: ApplicationFiled: March 4, 2021Publication date: March 16, 2023Inventors: Petr Sulc, Flavio Romano, John Russo, Lukas Kroc
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Patent number: 11605022Abstract: A device may receive, from a customer platform, customer event data identifying events occurring between customers and an entity, and may receive, from the customer platform, customer action data generated by machine learning models and identifying customer actions to be taken by the customer platform in response to the occurrence of the events. The device may receive, from the customer platform, customer results data identifying results of the customer actions taken by the customer platform, and may calculate current key performance indicators based on the customer event data, the customer action data, and the customer results data. The device may retrain one or more of the machine learning models based on the current key performance indicators to generate one or more retrained machine learning models, and may provide the one or more retrained machine learning models to the customer platform.Type: GrantFiled: October 21, 2019Date of Patent: March 14, 2023Assignee: Verizon Patent and Licensing Inc.Inventors: Vinod Khanna Saini Ganesh, Travis R. McLaren, Sailesh K. Mishra, Rajat Sharma, Pavani Kamalapuram, Pritam Bedse, Senthil Muthusamy, Rishi Kanth Chitti, John Russo, Srinivasan Krishnamurthy, Khagender Arrekuti
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Publication number: 20210117852Abstract: A device may receive, from a customer platform, customer event data identifying events occurring between customers and an entity, and may receive, from the customer platform, customer action data generated by machine learning models and identifying customer actions to be taken by the customer platform in response to the occurrence of the events. The device may receive, from the customer platform, customer results data identifying results of the customer actions taken by the customer platform, and may calculate current key performance indicators based on the customer event data, the customer action data, and the customer results data. The device may retrain one or more of the machine learning models based on the current key performance indicators to generate one or more retrained machine learning models, and may provide the one or more retrained machine learning models to the customer platform.Type: ApplicationFiled: October 21, 2019Publication date: April 22, 2021Inventors: Vinod Khanna Saini GANESH, Travis R. McLAREN, Sailesh K. MISHRA, Rajat SHARMA, Pavini KAMALAPURAM, Pritam BEDSE, Senthil MUTHUSAMY, Rishi Kanth CHITTI, John RUSSO, Srinivasan KRISHNAMURTHY, Khagender ARREKUTI
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Publication number: 20210093672Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: ApplicationFiled: December 14, 2020Publication date: April 1, 2021Applicant: MiMedx Group, Inc.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
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Patent number: 10874697Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: GrantFiled: September 26, 2017Date of Patent: December 29, 2020Assignee: MiMedx Group, Inc.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
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Patent number: 10409570Abstract: A processing device includes an instruction memory to store executable applications that are executable by a target processor, and a compiler. The compiler includes a builder module and a call graph generator. The builder module to build executable applications for the target processor based on a set of instructions. The call graph generator to create a first call graph that indicates a stack usage for each call path of the executable applications. If a first executable application built by the builder module includes a call path that exceeds a stack size constraint of the target processor, the builder module to optimize only functions within the call path that exceeds the stack size constraint in response to the request from the evaluation monitor, and to build a second executable application based on the set of instructions. The second executable application is optimized for stack memory usage of the target processor.Type: GrantFiled: October 19, 2016Date of Patent: September 10, 2019Assignee: NXP USA, Inc.Inventors: Michal Silbermintz, John Russo
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Publication number: 20180235254Abstract: A confection containing device that contains a confection consumed frozen. The device includes a stick-spout-pouch assembly, and a stick cap. The stick-spout-pouch assembly includes a latching portion integral with a stick portion, and a pouch bag attached to the latching portion. The stick cap attaches to the latching portion of the stick-spout-pouch assembly. The pouch bag contains a confection in a non-frozen state surrounding the stick portion of the stick-spout-pouch assembly. The pouch bag of the stick-spout-pouch assembly is sealed to the latching portion of the stick-spout-pouch assembly. The stick cap attaches to the latching portion of the stick-spout-pouch assembly by a sealed connection. Further, the pouch bag is filled with the confection in a liquid state through at least one opening on the stick-spout-pouch assembly. The opening is on the latching portion of the stick-spout-pouch assembly.Type: ApplicationFiled: March 1, 2017Publication date: August 23, 2018Applicant: Global Italian Ices Inc.Inventors: Gregory BROCCOLI, Maria ARENA, Peter GROSZ, John RUSSO
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Publication number: 20180107465Abstract: A processing device includes an instruction memory to store executable applications that are executable by a target processor, and a compiler. The compiler includes a builder module and a call graph generator. The builder module to build executable applications for the target processor based on a set of instructions. The call graph generator to create a first call graph that indicates a stack usage for each call path of the executable applications. If a first executable application built by the builder module includes a call path that exceeds a stack size constraint of the target processor, the builder module to optimize only functions within the call path that exceeds the stack size constraint in response to the request from the evaluation monitor, and to build a second executable application based on the set of instructions. The second executable application is optimized for stack memory usage of the target processor.Type: ApplicationFiled: October 19, 2016Publication date: April 19, 2018Inventors: Michal Silbermintz, John Russo
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Publication number: 20180085404Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: ApplicationFiled: September 26, 2017Publication date: March 29, 2018Applicant: MiMedx Group, Inc.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
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Patent number: 9789137Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: GrantFiled: July 20, 2015Date of Patent: October 17, 2017Assignee: MiMedx Group, Inc.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
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Patent number: 9533011Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: GrantFiled: February 3, 2014Date of Patent: January 3, 2017Assignee: MiMedx Group, Inc.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
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Patent number: 9415074Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: GrantFiled: October 21, 2015Date of Patent: August 16, 2016Assignee: MiMedx Group, Inc.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
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Patent number: 9272003Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: GrantFiled: April 25, 2014Date of Patent: March 1, 2016Assignee: MiMedx Group, Inc.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
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Publication number: 20160038638Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: ApplicationFiled: October 21, 2015Publication date: February 11, 2016Applicant: MIMEDX GROUP, INC.Inventors: John DANIEL, Randall SPENCER, John RUSSO, Robert TOFE
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Publication number: 20160030633Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: ApplicationFiled: July 20, 2015Publication date: February 4, 2016Applicant: MIMEDX GROUP, INC.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
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Patent number: 9084767Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.Type: GrantFiled: July 3, 2014Date of Patent: July 21, 2015Assignee: MiMedx Group, Inc.Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe