Patents by Inventor John Russo

John Russo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250140432
    Abstract: A method of making a radioisotopic power source, including receiving a predetermined amount of a plurality of Metal-Organic Framework (MOF) particles within a reactor vessel, degassing the received predetermined amount of the MOF. The degassing includes placing the predetermined amount of the MOF under vacuum conditions, heating the received predetermined amount of the MOF above a first predetermined temperature for a first predetermined time period, and sealing the heated MOF. The method also includes cooling the heated and sealed predetermined amount of the MOF to a second predetermined temperature, while maintaining a pressure of the reactor vessel to a first predetermined pressure value for a second predetermined time period, receiving a predetermined amount of a plurality of beta emitter particles at a gaseous state and mixing the predetermined amount of beta emitter particles with the cooled predetermined amount of the MOF.
    Type: Application
    Filed: October 28, 2023
    Publication date: May 1, 2025
    Applicant: Direct Kinetic Solutions Inc
    Inventors: Brenda Ann Smith, John Russo, William Ray, II
  • Publication number: 20240311527
    Abstract: A computer-implemented system uses multiscale modeling and optimization algorithms to design DNA nanostructures that self-assemble into a target structure, such as a tetrastack lattice. The system converts a target structure into a Boolean Satisfiability problem and models nanostructure units as “patchy” nanostructure models, where patches encode kinetic properties that affect how each nanostructure model connects with other nanostructure models. The system iteratively simulates self-assembly of a plurality of nanostructure models into a nanostructure assembly model, and compares the nanostructure assembly model with the target structure to determine a set of optimal parameters (such as patch type assignments) for the nanostructure units that reliably result in self-assembly into the target structure.
    Type: Application
    Filed: March 15, 2024
    Publication date: September 19, 2024
    Inventors: Petr Sulc, Michael Matthies, Flavio Romano, John Russo, Hao Liu
  • Publication number: 20230414670
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Application
    Filed: September 11, 2023
    Publication date: December 28, 2023
    Applicant: MiMedx Group, Inc.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
  • Patent number: 11752174
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Grant
    Filed: December 14, 2020
    Date of Patent: September 12, 2023
    Assignee: MiMedx Group, Inc.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
  • Publication number: 20230081282
    Abstract: A general framework which transforms the inverse problem of self-assembly of colloidal crystals into a Boolean satisfiability problem for which solutions can be found numerically is described herein. Given a reference structure and the desired number of components, our approach produces designs for which the target structure is an energy minimum, and also allows to exclude solutions that correspond to competing structures.
    Type: Application
    Filed: March 4, 2021
    Publication date: March 16, 2023
    Inventors: Petr Sulc, Flavio Romano, John Russo, Lukas Kroc
  • Patent number: 11605022
    Abstract: A device may receive, from a customer platform, customer event data identifying events occurring between customers and an entity, and may receive, from the customer platform, customer action data generated by machine learning models and identifying customer actions to be taken by the customer platform in response to the occurrence of the events. The device may receive, from the customer platform, customer results data identifying results of the customer actions taken by the customer platform, and may calculate current key performance indicators based on the customer event data, the customer action data, and the customer results data. The device may retrain one or more of the machine learning models based on the current key performance indicators to generate one or more retrained machine learning models, and may provide the one or more retrained machine learning models to the customer platform.
    Type: Grant
    Filed: October 21, 2019
    Date of Patent: March 14, 2023
    Assignee: Verizon Patent and Licensing Inc.
    Inventors: Vinod Khanna Saini Ganesh, Travis R. McLaren, Sailesh K. Mishra, Rajat Sharma, Pavani Kamalapuram, Pritam Bedse, Senthil Muthusamy, Rishi Kanth Chitti, John Russo, Srinivasan Krishnamurthy, Khagender Arrekuti
  • Publication number: 20210117852
    Abstract: A device may receive, from a customer platform, customer event data identifying events occurring between customers and an entity, and may receive, from the customer platform, customer action data generated by machine learning models and identifying customer actions to be taken by the customer platform in response to the occurrence of the events. The device may receive, from the customer platform, customer results data identifying results of the customer actions taken by the customer platform, and may calculate current key performance indicators based on the customer event data, the customer action data, and the customer results data. The device may retrain one or more of the machine learning models based on the current key performance indicators to generate one or more retrained machine learning models, and may provide the one or more retrained machine learning models to the customer platform.
    Type: Application
    Filed: October 21, 2019
    Publication date: April 22, 2021
    Inventors: Vinod Khanna Saini GANESH, Travis R. McLAREN, Sailesh K. MISHRA, Rajat SHARMA, Pavini KAMALAPURAM, Pritam BEDSE, Senthil MUTHUSAMY, Rishi Kanth CHITTI, John RUSSO, Srinivasan KRISHNAMURTHY, Khagender ARREKUTI
  • Publication number: 20210093672
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Application
    Filed: December 14, 2020
    Publication date: April 1, 2021
    Applicant: MiMedx Group, Inc.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
  • Patent number: 10874697
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: December 29, 2020
    Assignee: MiMedx Group, Inc.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
  • Patent number: 10409570
    Abstract: A processing device includes an instruction memory to store executable applications that are executable by a target processor, and a compiler. The compiler includes a builder module and a call graph generator. The builder module to build executable applications for the target processor based on a set of instructions. The call graph generator to create a first call graph that indicates a stack usage for each call path of the executable applications. If a first executable application built by the builder module includes a call path that exceeds a stack size constraint of the target processor, the builder module to optimize only functions within the call path that exceeds the stack size constraint in response to the request from the evaluation monitor, and to build a second executable application based on the set of instructions. The second executable application is optimized for stack memory usage of the target processor.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: September 10, 2019
    Assignee: NXP USA, Inc.
    Inventors: Michal Silbermintz, John Russo
  • Publication number: 20180235254
    Abstract: A confection containing device that contains a confection consumed frozen. The device includes a stick-spout-pouch assembly, and a stick cap. The stick-spout-pouch assembly includes a latching portion integral with a stick portion, and a pouch bag attached to the latching portion. The stick cap attaches to the latching portion of the stick-spout-pouch assembly. The pouch bag contains a confection in a non-frozen state surrounding the stick portion of the stick-spout-pouch assembly. The pouch bag of the stick-spout-pouch assembly is sealed to the latching portion of the stick-spout-pouch assembly. The stick cap attaches to the latching portion of the stick-spout-pouch assembly by a sealed connection. Further, the pouch bag is filled with the confection in a liquid state through at least one opening on the stick-spout-pouch assembly. The opening is on the latching portion of the stick-spout-pouch assembly.
    Type: Application
    Filed: March 1, 2017
    Publication date: August 23, 2018
    Applicant: Global Italian Ices Inc.
    Inventors: Gregory BROCCOLI, Maria ARENA, Peter GROSZ, John RUSSO
  • Publication number: 20180107465
    Abstract: A processing device includes an instruction memory to store executable applications that are executable by a target processor, and a compiler. The compiler includes a builder module and a call graph generator. The builder module to build executable applications for the target processor based on a set of instructions. The call graph generator to create a first call graph that indicates a stack usage for each call path of the executable applications. If a first executable application built by the builder module includes a call path that exceeds a stack size constraint of the target processor, the builder module to optimize only functions within the call path that exceeds the stack size constraint in response to the request from the evaluation monitor, and to build a second executable application based on the set of instructions. The second executable application is optimized for stack memory usage of the target processor.
    Type: Application
    Filed: October 19, 2016
    Publication date: April 19, 2018
    Inventors: Michal Silbermintz, John Russo
  • Publication number: 20180085404
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Application
    Filed: September 26, 2017
    Publication date: March 29, 2018
    Applicant: MiMedx Group, Inc.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
  • Patent number: 9789137
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: October 17, 2017
    Assignee: MiMedx Group, Inc.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
  • Patent number: 9533011
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Grant
    Filed: February 3, 2014
    Date of Patent: January 3, 2017
    Assignee: MiMedx Group, Inc.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
  • Patent number: 9415074
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Grant
    Filed: October 21, 2015
    Date of Patent: August 16, 2016
    Assignee: MiMedx Group, Inc.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
  • Patent number: 9272003
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: March 1, 2016
    Assignee: MiMedx Group, Inc.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
  • Publication number: 20160038638
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Application
    Filed: October 21, 2015
    Publication date: February 11, 2016
    Applicant: MIMEDX GROUP, INC.
    Inventors: John DANIEL, Randall SPENCER, John RUSSO, Robert TOFE
  • Publication number: 20160030633
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Application
    Filed: July 20, 2015
    Publication date: February 4, 2016
    Applicant: MIMEDX GROUP, INC.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe
  • Patent number: 9084767
    Abstract: Described herein are tissue grafts derived from the placenta. The grafts are composed of at least one layer of amnion tissue where the epithelium layer has been substantially removed in order to expose the basement layer to host cells. By removing the epithelium layer, cells from the host can more readily interact with the cell-adhesion bio-active factors located onto top and within of the basement membrane. Also described herein are methods for making and using the tissue grafts. The laminin structure of amnion tissue is nearly identical to that of native human tissue such as, for example, oral mucosa tissue. This includes high level of laminin-5, a cell adhesion bio-active factor show to bind gingival epithelia-cells, found throughout upper portions of the basement membrane.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: July 21, 2015
    Assignee: MiMedx Group, Inc.
    Inventors: John Daniel, Randall Spencer, John Russo, Robert Tofe