Patents by Inventor John Ryan Coombs

John Ryan Coombs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR MAKING AN EP4 ANTAGONIST
    Publication number: 20250092008
    Abstract: The present disclosure provides the methods for making 4-[4-cyano-2-({[(2?R,4S)-6-(isopropylcarbamoyl)-2,3-dihydrospiro[chromene-4,1?-cyclopropan]-2?-yl]carbonyl}amino)phenyl]butanoic acid. The present disclosure also generally relates to intermediates useful in the said methods.
    Type: Application
    Filed: August 9, 2022
    Publication date: March 20, 2025
    Applicant: ONO PHARMACEUTICAL CO., LTD.
    Inventors: Ryoichi ARIHARA, Naoya SAGAWA, Michael Bryan HAY, Sarah Evelyn STEINHARDT, Steven R. WISNIEWSKI, John Ryan COOMBS, Gregory Louis BEUTNER, Patricia Y. CHO, Carlos A. GUERRERO, Miao YU, Xuelei GUO
  • Synthetic process
    Patent number: 11332442
    Abstract: The invention generally relates to a process for preparing compounds, including Compound of Formula (I), useful as key intermediates in the preparation of compounds having ROR?t antagonist properties.
    Type: Grant
    Filed: August 12, 2020
    Date of Patent: May 17, 2022
    Assignees: Bristol-Myers Squibb Company, Syngene International Limited
    Inventors: William P. Gallagher, John Ryan Coombs, Carlos A. Guerrero, David Marcoux, Qing Shi, Candice Lee Joe, Sanjeewa Rupasinghe, Jason J. Zhu, Srinivas Kalidindi, Sathasivam Shunmugaraj, Moorthy Kandasamy, Siva Sankar Bondigela, Rajappa Vaidyanathan, Shankar Tulsidas Tendulkar, Sankar Kuppusamy, Francisco González-Bobes
  • SYNTHETIC PROCESS
    Publication number: 20220048859
    Abstract: The invention generally relates to a process for preparing compounds, including Compound of Formula (I), useful as key intermediates in the preparation of compounds having ROR?t antagonist properties.
    Type: Application
    Filed: August 12, 2020
    Publication date: February 17, 2022
    Inventors: William P. Gallagher, John Ryan Coombs, Carlos A. Guerrero, David Marcoux, Qing Shi, Candice Lee Joe, Sanjeewa Rupasinghe, Jason J. Zhu, Srinivas Kalidindi, Sathasivam Shunmugaraj, Moorthy Kandasamy, Siva Sankar Bondigela, Rajappa Vaidyanathan, Shankar Tulsidas Tendulkar, Sankar Kuppusamy, Francisco González-Bobes