Patents by Inventor John Ryan Thompson

John Ryan Thompson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR MAKING FLEXIBLE, POROUS, DISSOLVABLE SOLID SHEET ARTICLES WITH IMPROVED PORE STRUCTURES
    Publication number: 20240092990
    Abstract: This provides an improved process for making a flexible, porous, dissolvable solid sheet article with improved pore structures.
    Type: Application
    Filed: November 8, 2023
    Publication date: March 21, 2024
    Inventors: Hongsing TAN, Robert Wayne GLENN, JR., Carl David MAC NAMARA, Todd Ryan THOMPSON, Jason Allen STAMPER, John Philip HECHT, Xu HUANG, Ruizhi PEI, Paolo Efrain PALACIO MANCHENO, Toshiyuki OKADA
  • OLIGONUCLEOTIDES FOR MODULATING MYH7 EXPRESSION
    Publication number: 20210371860
    Abstract: The present invention relates to antisense oligonucleotides that are capable of modulating expression of MYH7 in a target cell. The oligonucleotides hybridize to MYH7 mRNA. The present invention further relates to conjugates of the oligonucleotide and pharmaceutical compositions and methods for treatment of hypertrophic cardiomyopathy using the oligonucleotide.
    Type: Application
    Filed: May 7, 2019
    Publication date: December 2, 2021
    Applicant: Roche Innovation Center Copenhagen A/S
    Inventors: Peter HAGEDORN, Richard OLSON, Marianne JENSEN, Annapurna PENDRI, Brian ANDERSON, Sean Carl LITTLE, Linda Jane BRISTOW, John Ryan THOMPSON, Ron AMMAR
  • Methods for characterizing agonists and partial agonists of target molecules
    Patent number: 8744778
    Abstract: In one aspect, the present invention provides methods of determining whether an agent is more like a partial agonist of a target molecule than a full agonist of the same target molecule. In another aspect, the present invention provides methods to select a candidate compound that may reduce blood plasma glucose concentration in a mammal. Populations of genes are provided that are useful in the practice of the present invention.
    Type: Grant
    Filed: August 12, 2011
    Date of Patent: June 3, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Yejun Tan, Hongyue Dai, Pek Yee Lum, John Ryan Thompson, Joel Peter Berger, Eric Stanley Muise, Richard F. Raubertas, Kenny Kin Chung Wong
  • METHODS FOR CHARACTERIZING AGONISTS AND PARTIAL AGONISTS OF TARGET MOLECULES
    Publication number: 20110294696
    Abstract: In one aspect, the present invention provides methods of determining whether an agent is more like a partial agonist of a target molecule than a full agonist of the same target molecule. In another aspect, the present invention provides methods to select a candidate compound that may reduce blood plasma glucose concentration in a mammal. Populations of genes are provided that are useful in the practice of the present invention.
    Type: Application
    Filed: August 12, 2011
    Publication date: December 1, 2011
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Yejun Tan, Hongyue Dai, Pek Yee Lum, John Ryan Thompson, Joel Peter Berger, Eric Stanley Muise, Richard F. Raubertas, Kenny Kin Chung Wong
  • Methods for characterizing agonists and partial agonists of target molecules
    Patent number: 8014954
    Abstract: In one aspect, the present invention provides methods of determining whether an agent is more like a partial agonist of a target molecule than a full agonist of the same target molecule. In another aspect, the present invention provides methods to select a candidate compound that may reduce blood plasma glucose concentration in a mammal. Populations of genes are provided that are useful in the practice of the present invention.
    Type: Grant
    Filed: April 4, 2006
    Date of Patent: September 6, 2011
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Yejun Tan, Hongyue Dai, Pek Yee Lum, John Ryan Thompson, Joel Peter Berger, Eric Stanley Muise, Richard F Raubertas, Kenny Kin Chung Wong