Patents by Inventor John S. Bergmann

John S. Bergmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatuses and methods for forming wounds in cell layers
    Patent number: 9664600
    Abstract: In one embodiment, an apparatus for forming wounds in cell layers includes a base that includes a guide track, and a sliding member adapted to fit within the guide track, the sliding member including a scratching element holder adapted to secure a scratching element in a position in which it contacts a cell layer, wherein the sliding member is further adapted to slide along the guide track to drag the scratching element through the cell layer.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: May 30, 2017
    Assignee: The Board of Regents of the University of Texas System
    Inventors: John S. Bergmann, Celeste C. Finnerty, David N. Herndon
  • Apparatuses And Methods For Forming Wounds In Cell Layers
    Publication number: 20150024425
    Abstract: In one embodiment, an apparatus for forming wounds in cell layers includes a base that includes a guide track, and a sliding member adapted to fit within the guide track, the sliding member including a scratching element holder adapted to secure a scratching element in a position in which it contacts a cell layer, wherein the sliding member is further adapted to slide along the guide track to drag the scratching element through the cell layer.
    Type: Application
    Filed: July 22, 2014
    Publication date: January 22, 2015
    Applicant: Board of Regents, The University of Texas System
    Inventors: John S. Bergmann, Celeste C. Finnerty, David N. Herndon
  • Antibodies to complementary peptides of thrombin or portions thereof
    Patent number: 7935341
    Abstract: Disclosed are antibodies and antigen-binding fragments that bind to a complementary peptide having an amino acid sequence that is encoded by the complement of a nucleotide sequence encoding thrombin or a portion thereof. Such antibodies and antigen-binding fragments can be agonists or antagonists of thrombin receptor-mediated events. Also disclosed are methods of using the agonist antibodies and antigen-binding fragments of the invention to activate the non-proteolytically activated thrombin receptor (NPAR) in a subject in need of such treatment. In addition, methods of using the antagonist antibodies and antigen-binding fragments of the invention to inhibit activation of the NPAR in a subject in need of such treatment are disclosed.
    Type: Grant
    Filed: September 14, 2006
    Date of Patent: May 3, 2011
    Assignee: Orthologic Corp.
    Inventors: Darrell H. Carney, John S. Bergmann, Gerald M. Fuller
  • Antibodies to complementary peptides of thrombin or portions thereof
    Publication number: 20080241149
    Abstract: Disclosed are antibodies and antigen-binding fragments that bind to a complementary peptide having an amino acid sequence that is encoded by the complement of a nucleotide sequence encoding thrombin or a portion thereof. Such antibodies and antigen-binding fragments can be agonists or antagonists of thrombin receptor-mediated events. Also disclosed are methods of using the agonist antibodies and antigen-binding fragments of the invention to activate the non-proteolytically activated thrombin receptor (NPAR) in a subject in need of such treatment. In addition, methods of using the antagonist antibodies and antigen-binding fragments of the invention to inhibit activation of the NPAR in a subject in need of such treatment are disclosed.
    Type: Application
    Filed: September 14, 2006
    Publication date: October 2, 2008
    Inventors: Darrell H. Carney, John S. Bergmann, Gerald M. Fuller