Patents by Inventor John S. Bomalaski

John S. Bomalaski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treatment with arginine deiminase
    Patent number: 10525142
    Abstract: The present invention relates generally to methods of treating cancer with arginine deiminase, and in particular pegylated arginine deiminase.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: January 7, 2020
    Assignee: Polaris Group
    Inventors: John S. Bomalaski, Bor-Wen Wu
  • METHODS OF TREATMENT WITH ARGININE DEIMINASE
    Publication number: 20180154008
    Abstract: The present invention relates generally to methods of treating cancer with arginine deiminase, and in particular pegylated arginine deiminase.
    Type: Application
    Filed: July 12, 2017
    Publication date: June 7, 2018
    Inventors: John S. Bomalaski, Bor-Wen Wu
  • Methods of treatment with arginine deiminase
    Patent number: 9731028
    Abstract: The present invention relates generally to methods of treating cancer with arginine deiminase, and in particular pegylated arginine deiminase.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: August 15, 2017
    Assignee: Polaris Group
    Inventors: John S. Bomalaski, Bor-Wen Wu
  • Methods of treatment with arginine deiminase
    Patent number: 9333268
    Abstract: The present invention relates generally to methods of treating cancer with arginine deiminase, and in particular pegylated arginine deiminase.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: May 10, 2016
    Assignee: Polaris Group
    Inventors: John S. Bomalaski, Bor-Wen Wu
  • METHODS OF TREATMENT WITH ARGININE DEIMINASE
    Publication number: 20150231272
    Abstract: The present invention relates generally to methods of treating cancer with arginine deiminase, and in particular pegylated arginine deiminase.
    Type: Application
    Filed: May 1, 2015
    Publication date: August 20, 2015
    Inventors: John S. Bomalaski, Bor-Wen Wu
  • METHODS OF TREATMENT WITH ARGININE DEIMINASE
    Publication number: 20150132278
    Abstract: The present invention relates generally to methods of treating cancer with arginine deiminase, and in particular pegylated arginine deiminase.
    Type: Application
    Filed: May 30, 2012
    Publication date: May 14, 2015
    Inventors: John S. Bomalaski, Bor-Wen Wu
  • Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis
    Patent number: 5786154
    Abstract: The invention provides methods for detecting elevated levels of phospholipase A.sub.2 activating protein in persons suspected of having rheumatoid arthritis to thereby indicate the presence of rheumatoid arthritis in the person comprising the steps of providing a sample of body fluid or tissue from said person; contacting the sample with an antibody specific for phospholipase A.sub.2 activating protein such that the antibody binds with phospholipase A.sub.2 activating protein in the sample; detecting the antibody thereby indicating the presence of phospholipase A.sub.2 activating protein, whereby elevated levels of phospholipase A.sub.2 activating protein in the sample as compared with levels found in persons not having rheumatoid arthritis indicates the presence of rheumatoid arthritis in the person. Kits and reagents for detecting rheumatoid arthritis are also provided.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: July 28, 1998
    Inventors: John S. Bomalaski, Mike A. Clark, Robert Shorr
  • DNA encoding phospholipase activating protein
    Patent number: 5580968
    Abstract: The invention provides methods for detecting elevated levels of phospholipase A.sub.2 activating protein in persons suspected of having rheumatoid arthritis to thereby indicate the presence of rheumatoid arthritis in the person comprising the steps of providing a sample of body fluid or tissue from said person; contacting the sample with an antibody specific for phospholipase A.sub.2 activating protein such that the antibody binds with phospholipase A.sub.2 activating protein in the sample; detecting the antibody thereby indicating the presence of phospholipase A.sub.2 activating protein, whereby elevated levels of phospholipase A.sub.2 activating protein in the sample as compared with levels found in persons not having rheumatoid arthritis indicates the presence of rheumatoid arthritis in the person. Kits and reagents for detecting rheumatoid arthritis are also provided.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: December 3, 1996
    Inventors: John S. Bomalaski, Michael A. Clark, Robert Shorr
  • Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis
    Patent number: 5367063
    Abstract: The invention provides methods for detecting elevated levels of phospholipase A.sub.2 activating protein in persons suspected of having rheumatiod arthritis to thereby indicate the presence of rheumatoid arthritis in the person comprising the steps of providing a sample of body fluid or tissue from said person; contacting the sample with an antibody specific for phospholipase A.sub.2 activating protein such that the antibody binds with phospholipase A.sub.2 activating protein in the sample; detecting the antibody thereby indicating the presence of phospholipase A.sub.2 activating protein, whereby elevated levels of phospholipase A.sub.2 activating protein in the sample as compared with levels found in persons not having rheumatoid arthritis indicates the presence of rheumatoid arthritis in the person. Kits and reagents for detecting rheumatoid arthritis are also provided.
    Type: Grant
    Filed: November 4, 1993
    Date of Patent: November 22, 1994
    Inventors: John S. Bomalaski, Mike A. Clark, Robert Shorr
  • Human phospholipase activating protein and methods for diagnosis of rheumatoid arthritis
    Patent number: 5294698
    Abstract: The invention provides methods for detecting elevated levels of phospholipase A.sub.2 activating protein in persons suspected of having rheumatiod arthritis to thereby indicate the presence of rheumatoid arthritis in the person comprising the steps of providing a sample of body fluid or tissue from said person; contacting the sample with an antibody specific for phospholipase A.sub.2 activating protein such that the antibody binds with phospholipase A.sub.2 activating protein in the sample; detecting the antibody thereby indicating the presence of phospholipase A.sub.2 activating protein, whereby elevated levels of phospholipase A.sub.2 activating protein in the sample as compared with levels found in persons not having rheumatoid arthritis indicates the presence of rheumatoid arthritis in the person. Kits and reagents for detecting rheumatoid arthritis are also provided.
    Type: Grant
    Filed: December 6, 1990
    Date of Patent: March 15, 1994
    Inventors: John S. Bomalaski, Michael A. Clark, Robert Shorr