Patents by Inventor John S. Kiely

John S. Kiely has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel enolamides, pharmaceutical compositions and methods of use thereof for activity as modulators of the arachidonic acid cascade
    Patent number: 4868205
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: March 11, 1988
    Date of Patent: September 19, 1989
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Substituted diimidazo [1,5-a: 4',5'-d]pyridines having antihypertensive activity
    Patent number: 4816463
    Abstract: This invention relates to novel substituted derivatives of diimidazo[1,5-a:4',5'-d]pyridines and analogs thereof, which are useful for the treatment of hypertension, as well as, novel pharmaceutical compositions, methods of use, and as intermediates for preparing novel substituted derivatives of 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid and analogs thereof having antihypertensive activity.
    Type: Grant
    Filed: April 7, 1987
    Date of Patent: March 28, 1989
    Assignee: Warner-Lambert Company
    Inventors: C. John Blankley, John C. Hodges, John S. Kiely, Sylvester R. Klutchko
  • 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid analogs having antihypertensive activity
    Patent number: 4812462
    Abstract: This invention relates to novel substituted derivatives of 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid and analogs thereof, which are useful for the treatment of hypertension, as well as, novel pharmaceutical compositions and methods of use.
    Type: Grant
    Filed: April 1, 1986
    Date of Patent: March 14, 1989
    Assignee: Warner-Lambert Company
    Inventors: C. John Blankley, John C. Hodges, John S. Kiely, Sylvester R. Klutchko
  • Diphenic acid monoamides
    Patent number: 4786755
    Abstract: The present invention provides various novel diphenic acid monoamide compounds, novel pharmaceutical compositions and methods of use thereof, as well as novel methods of synthesis therefor. The novel diphenic acid monoamides of the present invention are leukotriene antagonists, 5-lipoxygenase inhibitors, and mediator release inhibitors providing activity useful for treating asthma, allergies, cardiovascular diseases, migraines, and immunoinflammatory conditions.
    Type: Grant
    Filed: April 2, 1986
    Date of Patent: November 22, 1988
    Assignee: Warner-Lambert Company
    Inventors: John S. Kiely, Suchin Huang
  • Enolamides, pharmaceutical compositions and methods for treating inflammation
    Patent number: 4761424
    Abstract: The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.
    Type: Grant
    Filed: October 1, 1985
    Date of Patent: August 2, 1988
    Assignee: Warner-Lambert Company
    Inventors: Mary E. Carethers, Wiaczeslaw A. Cetenko, David T. Connor, Elizabeth A. Johnson, John S. Kiely, Charles F. Schwender, Jagadish C. Sircar, Roderick J. Sorenson, Paul C. Unangst, Robert F. Bruns
  • Diphenic acid monoamides
    Patent number: 4602023
    Abstract: The present invention provides various novel diphenic acid monoamide compounds, novel pharmaceutical compositions and methods of use thereof, as well as novel methods of synthesis therefor. The novel diphenic acid monoamides of the present invention are leukotriene antagonists, 5-lipoxygenase inhibitors, and mediator release inhibitors providing activity useful for treating asthma, allergies, cardiovascular diseases, migraines, and immunoinflammatory conditions.
    Type: Grant
    Filed: June 3, 1985
    Date of Patent: July 22, 1986
    Assignee: Warner-Lambert Company
    Inventors: John S. Kiely, Suchin Huang