Patents by Inventor John S. Olson

John S. Olson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240097346
    Abstract: Methods for constructing multi-walled carbon nanotube (MWCNT) antenna arrays, may include: variable doping of the MWCNTs, forming light pipes with layers of variable dielectric glass, forming geometric diodes on full-wave rectified devices that propagate both electrons and holes, using clear conductive ground plans to form windows that can control a building's internal temperature, and generating multiple lithographic patterns with a single mask.
    Type: Application
    Filed: November 21, 2023
    Publication date: March 21, 2024
    Inventors: Laurence H. COOKE, Darin S. OLSON, Paul COMITA, Robert E. COUSINS, Albert K. HENNING, Andreas HEGEDUS, David B. COOKE, Yao Te CHENG, John BURKE, Richard T. PRESTON
  • Patent number: 11859177
    Abstract: Methods, systems, and apparatuses for employing nanobubbles for theranostic purposes are provided. In one embodiment, a method comprising introducing a photothermal nanobubble into a malaria-infected red blood cell is provided.
    Type: Grant
    Filed: July 26, 2019
    Date of Patent: January 2, 2024
    Assignee: WILLIAM MARSH RICE UNIVERSITY
    Inventors: Dmitri Lapotko, Katsiaryna Hleb, Janet Braam, John S. Olson
  • Publication number: 20190345478
    Abstract: Methods, systems, and apparatuses for employing nanobubbles for theranostic purposes are provided. In one embodiment, a method comprising introducing a photothermal nanobubble into a malaria-infected red blood cell is provided.
    Type: Application
    Filed: July 26, 2019
    Publication date: November 14, 2019
    Inventors: Dmitri Lapotko, Katsiaryna Hleb, Janet Braam, John S. Olson
  • Publication number: 20150072337
    Abstract: Methods, systems, and apparatuses for employing nanobubbles for theranostic purposes are provided. In one embodiment, a method comprising introducing a photothermal nanobubble into a malaria-infected red blood cell is provided.
    Type: Application
    Filed: July 16, 2014
    Publication date: March 12, 2015
    Inventors: Dmitri Lapotko, Katsiaryna Hleb, Janet Braam, John S. Olson
  • Patent number: 7803912
    Abstract: The disclosure relates to recombinant adult human apohemoglobin (apo-rHb) in which the stability has been increased by replacement of an amino acid with a counterpart from another organism, such as a deep sea diving mammal. This mutated apo-rHb may be more stable and/or give higher production yields than unmutated adult human apo-rHb. The mutated apo-rHb may be produced in microorganisms, such as E. coli or yeast cells, or animal erythroid cells. Some apo-rHb of the present disclosure may be used as part of a blood substitute.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: September 28, 2010
    Assignees: William Marsh Rice University, Wisconsin Alumni Research Foundation
    Inventors: John S. Olson, George N. Phillips, Jr.
  • Patent number: 7642233
    Abstract: The present disclosure relates to the use of AHSP to stabilize the ? subunit of rHb. AHSP may be co-expressed with the hemoglobin genes. AHSP stabilization may be used to increase the production of intact rHb in various systems, such as E. coli, other microorganisms, or animal erythroid cells. This intact rHb may then be used as part of a blood substitute product.
    Type: Grant
    Filed: March 14, 2007
    Date of Patent: January 5, 2010
    Assignees: William Marsh Rice University, The Children's Hospital of Philadelphia
    Inventors: John S. Olson, Mitchell J. Weiss
  • Patent number: 7049406
    Abstract: The invention relates to novel recombinant hemoglobins having reduced nitric oxide scavenging and/or increased high soluble expression. The invention further relates to methods of increasing the soluble expression of recombinant hemoglobin by adding exogenous hemin in molar excess of the heme binding sites of recombinant hemoglobin.
    Type: Grant
    Filed: March 27, 2002
    Date of Patent: May 23, 2006
    Assignees: Baxter Biotech Technology SARL, William Marsh Rice University
    Inventors: Michael J Weickert, Christopher B Glascock, Antony J Mathews, Douglas D Lemon, Daniel H Doherty, John S Olson
  • Patent number: 6812207
    Abstract: The present invention relates to methods of reducing heme loss in hemoglobins to produce stability and improve expression yield of hemoglobins, particularly recombinant hemoglobins. Such methods are accomplished by introducing mutations in the alpha or beta subunits of hemoglobins to increase heme affinity. The present invention further relates to novel mutations that reduce such heme loss.
    Type: Grant
    Filed: September 5, 2000
    Date of Patent: November 2, 2004
    Assignee: William Marsh Rice University
    Inventors: John S. Olson, Timothy L. Whitaker, Mark S. Hargrove
  • Publication number: 20030017537
    Abstract: The invention relates to novel recombinant hemoglobins having reduced nitric oxide scavenging and/or increased high soluble expression. The invention further relates to methods of increasing the soluble expression of recombinant hemoglobin by adding exogenous hemin in molar excess of the heme binding sites of recombinant hemoglobin.
    Type: Application
    Filed: March 27, 2002
    Publication date: January 23, 2003
    Applicant: Baxter Biotech Technology SARL William Marsh Rice Univ.
    Inventors: Michael J. Weickert, Christopher B. Glascock, Antony J. Mathews, Douglas D. Lemon, Daniel H. Doherty, John S. Olson
  • Patent number: 6455676
    Abstract: The invention relates to novel recombinant hemoglobins having reduced nitric oxide scavenging and/or increased high soluble expression. The invention further relates to methods of increasing the soluble expression of recombinant hemoglobin by adding exogenous hemin in molar excess of the heme binding sites of recombinant hemoglobin.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: September 24, 2002
    Assignees: Baxter Biotech Technology SARL, William Marsh Rice Univerisity
    Inventors: Michael J. Weickert, Christopher B. Glascock, Antony J. Mathews, Douglas D. Lemon, Daniel H. Doherty, John S. Olson
  • Patent number: 6204009
    Abstract: This invention relates to recombinant hemoglobins containing mutations in or near the heme pocket of the hemoglobin molecule. This invention particularly relates to recombinant hemoglobins that have altered geometry or polarity around the distal portion of the heme pocket.
    Type: Grant
    Filed: February 26, 1998
    Date of Patent: March 20, 2001
    Assignee: Baxter Biotech Technology Sàrl
    Inventors: John S. Olson, Antony J. Mathews, Jacqueline F. Aitken, Kyoshi Nagai
  • Patent number: 6114505
    Abstract: The present invention relates to methods of reducing heme loss in hemoglobins to produce stability and improve expression yield of hemoglobins, particularly recombinant hemoglobins. Such methods are accomplished by introducing mutations in the alpha or beta subunits of hemoglobins to increase heme affinity. The present invention further relates to novel mutations that reduce such heme loss.
    Type: Grant
    Filed: April 22, 1998
    Date of Patent: September 5, 2000
    Assignee: William Marsh Rice University
    Inventors: John S. Olson, Timothy L. Whitaker, Mark S. Hargrove
  • Patent number: 6106789
    Abstract: The invention provides an improved alkylation process and reactor apparatus. The invention utilizes a vessel containing a riser-reactor conduit, an acid settler and an acid cooler. Hydrocarbons are introduced beneath said riser-reactor conduit, mixed with acid catalyst, and passed generally upwards through the riser-reactor conduit to enter the acid settler. Within the acid settler, alkylate is separate from the acid catalyst and is removed from the vessel. Acid catalyst from the acid settler is cooled in the internal acid coolers and returned to the region beneath the riser-reactor conduit.
    Type: Grant
    Filed: December 30, 1993
    Date of Patent: August 22, 2000
    Assignee: Phillips Petroleum Company
    Inventors: Max W. Thompson, John S. Olson
  • Patent number: 6022849
    Abstract: This invention relates to recombinant hemoglobins containing mutations in or near the heme pocket of the hemoglobin molecule. This invention particularly relates to recombinant hemoglobins that have altered geometry or polarity around the distal portion of the heme pocket.
    Type: Grant
    Filed: January 30, 1995
    Date of Patent: February 8, 2000
    Assignee: Baxter Biotech Technology Saarl
    Inventors: John S. Olson, Antony J. Mathews, Jacqueline F. Aitken, Kyoshi Nagai
  • Patent number: 4746407
    Abstract: In a fractional distillation process, the operation of a reflux pump in the process is enhanced by providing that liquid discharged from the reflux pump is returned directly to the reflux pump suction during the periods when the liquid reflux supply from the fractional distillation process is not sufficient to keep the reflux pump in constant operation.
    Type: Grant
    Filed: February 20, 1987
    Date of Patent: May 24, 1988
    Assignee: Phillips Petroleum Company
    Inventor: John S. Olson
  • Patent number: 4351803
    Abstract: Hydrocarbons are preheated, particularly for a hydrodesulfurization process by first heating the hydrocarbon stream to produce a vapor and a liquid stream, thereafter superheating at least some of the vapor phase and mixing the superheated vapor phase with the liquid phase to generate the hydrocarbon feedstream at the desired temperature. By this procedure only the evaporated hydrocarbons are subjected to a high temperature, but not the heavier hydrocarbons.
    Type: Grant
    Filed: June 5, 1981
    Date of Patent: September 28, 1982
    Assignee: Phillips Petroleum Company
    Inventor: John S. Olson
  • Patent number: 4293402
    Abstract: Hydrocarbons are preheated, particularly for a hydrodesulfurization process by first heating the hydrocarbon stream to produce a vapor and a liquid stream, thereafter superheating at least some of the vapor phase and mixing the superheated vapor phase with the liquid phase to generate the hydrocarbon feedstream at the desired temperature. By this procedure only the evaporated hydrocarbons are subjected to a high temperature, but not the heavier hydrocarbons.
    Type: Grant
    Filed: March 10, 1980
    Date of Patent: October 6, 1981
    Assignee: Phillips Petroleum Company
    Inventor: John S. Olson