Patents by Inventor John S. Patton

John S. Patton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10525214
    Abstract: An aerosolization system includes a container that is configured to deliver a unit dosage of a liquid when squeezed a single time. The system also includes an aerosolizer that is constructed of a housing defining a mouthpiece, and an aerosol generator disposed in the housing. The aerosol generator includes a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane. Further, the housing includes an opening that is adapted to receive a unit dosage of the liquid from the container. The opening provides a liquid path to the rear face of the vibratable membrane.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: January 7, 2020
    Assignee: Dance Biopharm Inc.
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Publication number: 20190015611
    Abstract: A method is described for supplying a metered amount of a liquid medicament to an aerosolizing device. The method utilizes a dispenser comprising an elongate dispenser body having a proximal end and a tip at a distal end through which a liquid medicament is dispensed. The dispenser further comprises a dispensing mechanism that operates to dispense a metered quantity of the liquid medicament from the tip each time the dispenser body is compressed. The dispenser is grasped with one hand such that the fingers wrap around the dispenser body, with the thumb closest to the proximal end and the last finger closest to the tip. The tip is inserted into an opening of an inhaler and the elongate body is forced toward the tip to cause the dispenser body to compress, thereby operating the dispensing mechanism and causing a metered quantity of the liquid medicament to eject into the inhaler.
    Type: Application
    Filed: September 17, 2018
    Publication date: January 17, 2019
    Inventors: Ryan S. Patton, John S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Publication number: 20180353714
    Abstract: One embodiment describes an insulin formulation that is specifically adapted for aerosolization. The formulation comprises a major amount of water and a minor amount of insulin. Further, the formulation is preservative free, without meta-cresol, cresol or phenol, to permit the formulation to be aerosolized using a vibrating aperture plate without substantial foaming of the insulin formulation.
    Type: Application
    Filed: August 21, 2018
    Publication date: December 13, 2018
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Patent number: 10076613
    Abstract: One embodiment describes an insulin formulation that is specifically adapted for aerosolization. The formulation includes a major amount of water and a minor amount of insulin. Further, the formulation is preservative free, without meta-cresol, cresol or phenol, to permit the formulation to be aerosolized using a vibrating aperture plate without substantial foaming of the insulin formulation.
    Type: Grant
    Filed: October 8, 2015
    Date of Patent: September 18, 2018
    Assignee: Dance Biopharm Inc.
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Patent number: 9545488
    Abstract: An aerosolization system includes a container that is configured to deliver a unit dosage of a liquid when squeezed a single time. The system also includes an aerosolizer that is constructed of a housing defining a mouthpiece, and an aerosol generator disposed in the housing. The aerosol generator includes a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane. Further, the housing includes an opening that is adapted to receive a unit dosage of the liquid from the container. The opening provides a liquid path to the rear face of the vibratable membrane.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: January 17, 2017
    Assignee: Dance Biopharm Inc.
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Publication number: 20160271346
    Abstract: An aerosolization system includes a container that is configured to deliver a unit dosage of a liquid when squeezed a single time. The system also includes an aerosolizer that is constructed of a housing defining a mouthpiece, and an aerosol generator disposed in the housing. The aerosol generator includes a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane. Further, the housing includes an opening that is adapted to receive a unit dosage of the liquid from the container. The opening provides a liquid path to the rear face of the vibratable membrane.
    Type: Application
    Filed: May 26, 2016
    Publication date: September 22, 2016
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Publication number: 20160129088
    Abstract: One embodiment describes an insulin formulation that is specifically adapted for aerosolization. The formulation comprises a major amount of water and a minor amount of insulin. Further, the formulation is preservative free, without meta-cresol, cresol or phenol, to permit the formulation to be aerosolized using a vibrating aperture plate without substantial foaming of the insulin formulation.
    Type: Application
    Filed: October 8, 2015
    Publication date: May 12, 2016
    Applicant: Dance Biopharm Inc.
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Patent number: 9180261
    Abstract: One embodiment describes an insulin formulation that is specifically adapted for aerosolization. The formulation includes a major amount of water and a minor amount of insulin. Further, the formulation is preservative free, without meta-cresol, cresol or phenol, to permit the formulation to be aerosolized using a vibrating aperture plate without substantial foaming of the insulin formulation.
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: November 10, 2015
    Assignee: Dance Biopharm Inc.
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Publication number: 20150196721
    Abstract: An aerosolization system includes a container that is configured to deliver a unit dosage of a liquid when squeezed a single time. The system also includes an aerosolizer that is constructed of a housing defining a mouthpiece, and an aerosol generator disposed in the housing. The aerosol generator includes a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane. Further, the housing includes an opening that is adapted to receive a unit dosage of the liquid from the container. The opening provides a liquid path to the rear face of the vibratable membrane.
    Type: Application
    Filed: January 27, 2015
    Publication date: July 16, 2015
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Patent number: 9004061
    Abstract: An aerosolization system includes a container that is configured to deliver a unit dosage of a liquid when squeezed a single time. The system also includes an aerosolizer that is constructed of a housing defining a mouthpiece, and an aerosol generator disposed in the housing. The aerosol generator includes a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane. Further, the housing includes an opening that is adapted to receive a unit dosage of the liquid from the container. The opening provides a liquid path to the rear face of the vibratable membrane.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: April 14, 2015
    Assignee: Dance Biopharm, Inc.
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Patent number: 8950394
    Abstract: An aerosolization system includes a squeezable container having a resilient container body. The container is configured to deliver a unit dosage of a liquid when squeezed a single time. The system also includes an aerosolizer that is constructed of a housing defining a mouthpiece, and an aerosol generator disposed in the housing. The aerosol generator includes a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane. Further, the housing includes an opening that is adapted to receive a unit dosage of the liquid from the container. The opening provides a liquid path to the rear face of the vibratable membrane.
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: February 10, 2015
    Assignee: Dance Biopharm Inc.
    Inventors: John S. Patton, Ryan S. Patton, Mei-Chang Kuo, Yehuda Ivri
  • Publication number: 20140318533
    Abstract: A dispenser for supplying a metered volume of a liquid medicament to an aerosolizing device. The dispenser may include a container having a proximal end and a distal end, wherein the container is configured to store a volume of liquid medicament. The dispenser may also include a dispensing mechanism coupled to the distal end of the container. The dispensing mechanism may have a distal end terminating in a tip through which the liquid medicament is dispensed. The dispensing mechanism operates to dispense a metered volume of the liquid medicament from the tip each time the dispensing mechanism is operated. The distal end of the dispensing mechanism includes an interface that interacts with a housing of an inhaler to limit an insertion depth of the tip into an opening the housing.
    Type: Application
    Filed: April 16, 2014
    Publication date: October 30, 2014
    Inventors: John S. Patton, Ryan S. Patton, Lisa Molloy, Jim Fink
  • Publication number: 20140041653
    Abstract: An aerosolization system includes a container that is configured to deliver a unit dosage of a liquid when squeezed a single time. The system also includes an aerosolizer that is constructed of a housing defining a mouthpiece, and an aerosol generator disposed in the housing. The aerosol generator includes a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane. Further, the housing includes an opening that is adapted to receive a unit dosage of the liquid from the container. The opening provides a liquid path to the rear face of the vibratable membrane.
    Type: Application
    Filed: September 27, 2013
    Publication date: February 13, 2014
    Applicant: Dance Pharmaceuticals Inc.
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Publication number: 20110168172
    Abstract: An aerosolization system includes a squeezable container having a resilient container body. The container is configured to deliver a unit dosage of a liquid when squeezed a single time. The system also includes an aerosolizer that is constructed of a housing defining a mouthpiece, and an aerosol generator disposed in the housing. The aerosol generator comprises a vibratable membrane having a front face and a rear face, and a vibratable element used to vibrate the membrane. Further, the housing includes an opening that is adapted to receive a unit dosage of the liquid from the container. The opening provides a liquid path to the rear face of the vibratable membrane.
    Type: Application
    Filed: January 11, 2011
    Publication date: July 14, 2011
    Applicant: Dance Pharmaceuticals, Inc.
    Inventors: John S. Patton, Ryan S. Patton, Mei-Chang Kuo, Yehuda Ivri
  • Publication number: 20110168170
    Abstract: One embodiment describes an insulin formulation that is specifically adapted for aerosolization. The formulation comprises a major amount of water and a minor amount of insulin. Further, the formulation is preservative free, without meta-cresol, cresol or phenol, to permit the formulation to be aerosolized using a vibrating aperture plate without substantial foaming of the insulin formulation.
    Type: Application
    Filed: January 11, 2011
    Publication date: July 14, 2011
    Applicant: Dance Pharmaceuticals, Inc.
    Inventors: John S. Patton, Ryan S. Patton, Mei-chang Kuo, Yehuda Ivri
  • Publication number: 20090217928
    Abstract: An aerosolization device comprises a chamber adapted to contain a powder pharmaceutical formulation, a lid at least partially covering the chamber, at least one piercing element forcible through the lid to provide access to the powder pharmaceutical formulation, and a shapeable surface extending from the chamber, the shapeable surface being adapted to undergo a shape change to form a conduit. The powder pharmaceutical formulation may be extracted from the chamber by a user inhaling through the conduit. In another version, the lid is removable from the chamber without the need for a piercing element.
    Type: Application
    Filed: May 7, 2009
    Publication date: September 3, 2009
    Inventors: John S. Patton, Michael T. Newhouse
  • Publication number: 20090203576
    Abstract: Systemic delivery of insulin to a mammalian host is accomplished by inhalation of a dry powder of insulin. It has been found that dry insulin powders are rapidly absorbed through the alveolar regions of the lungs.
    Type: Application
    Filed: March 3, 2009
    Publication date: August 13, 2009
    Inventors: John S. Patton, Linda Foster, Robert M. Platz
  • Patent number: 7540284
    Abstract: An aerosolization device comprises a chamber adapted to contain a powder pharmaceutical formulation, a lid at least partially covering the chamber, at least one piercing element forcible through the lid to provide access to the powder pharmaceutical formulation, and a shapeable surface extending from the chamber, the shapeable surface being adapted to undergo a shape change to form a conduit. The powder pharmaceutical formulation may be extracted from the chamber by a user inhaling through the conduit. In another version, the lid is removable from the chamber without the need for a piercing element.
    Type: Grant
    Filed: June 19, 2002
    Date of Patent: June 2, 2009
    Assignee: Novartis Pharma AG
    Inventors: John S. Patton, Michael T. Newhouse
  • Patent number: 7521069
    Abstract: Systemic delivery of insulin to a mammalian host is accomplished by inhalation of a dry powder of insulin. It has been found that dry insulin powders are rapidly absorbed through the alveolar regions of the lungs.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: April 21, 2009
    Assignee: Novartis AG
    Inventors: John S. Patton, Linda S. Foster, Robert M. Platz
  • Patent number: 7456150
    Abstract: Systemic delivery of parathyroid hormone to a mammalian host is accomplished by inhalation through the mouth of a dispersion of an N-terminal fragment of PTH. It has been found that such respiratory delivery of the PTH fragment provides a pulsatile concentration profile of the PTH in the host's serum. PTH fragment compositions include dry powder formulations having the PTH present in a dry bulking powder, liquid solutions or suspensions suitable for nebulization, and aerosol propellants suitable for use in a metered dose inhaler.
    Type: Grant
    Filed: May 22, 2000
    Date of Patent: November 25, 2008
    Assignee: Mektar Therapeutics
    Inventor: John S. Patton