Patents by Inventor John S. Rudge

John S. Rudge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating inflammatory skin diseases
    Publication number: 20040266686
    Abstract: Methods of treating diseases in which plasma leakage and/or vascular permeability occurs, for example, inflammatory skin diseases, particularly psoriasis, with a vascular endothelial growth factor (VEGF) antagonist. Further included are methods for enhacing wound healing with a VEGF antagonist.
    Type: Application
    Filed: April 16, 2004
    Publication date: December 30, 2004
    Inventors: Yuping Xia, John S. Rudge, George D. Yancopoulos
  • Methods of treating inflammatory skin diseases
    Patent number: 6833349
    Abstract: Modified chimeric polypeptides with improved pharmacokinetics are disclosed. Specifically, modified chimeric Flt1 receptor polypeptides that have been modified in such a way as to improve their pharmacokinetic profile are disclosed. Also disclosed are methods of making and using the modified polypeptides including but not limited to using the modified polypeptides to decrease or inhibit plasma leakage and/or vascular permeability in a mammal. Also disclosed are methods of treating diseases in which plasma leakage and/or vascular permeability occurs, for example, inflammatory skin diseases.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: December 21, 2004
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Yuping Xia, John S. Rudge, George D. Yancopoulos
  • Methods of treating inflammatory skin diseases
    Publication number: 20030017977
    Abstract: Modified chimeric polypeptides with improved pharmacokinetics are disclosed. Specifically, modified chimeric Fit1 receptor polypeptides that have been modified in such a way as to improve their pharmacokinetic profile are disclosed. Also disclosed are methods of making and using the modified polypeptides including but not limited to using the modified polypeptides to decrease or inhibit plasma leakage and/or vascular permeability in a mammal. Also disclosed are methods of treating diseases in which plasma leakage and/or vascular permeability occurs, for example, inflammatory skin diseases.
    Type: Application
    Filed: January 31, 2001
    Publication date: January 23, 2003
    Inventors: Yuping Xia, John S. Rudge, George D. Yancopoulos