Patents by Inventor John Sandy

John Sandy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic target for musculoskeletal inflammation
    Patent number: 11655506
    Abstract: A method for monitoring a treatment of a subject having a musculoskeletal disorder is provided. The method includes measuring a first expression level of at least two biomarkers at a treatment site prior to the treatment and measuring a second expression level of the at least two biomarkers at the treatment site after the treatment begins. The method further includes comparing the first expression level of the at least two biomarkers prior to the treatment to the second expression level of the at least two biomarkers post treatment and continuing the treatment, altering the treatment or stopping the treatment based on the comparison. A method of treating a musculoskeletal disorder in a subject is also provided. The method includes removing a aggrecan-hyaluronan matrix from a treatment site in the subject.
    Type: Grant
    Filed: January 14, 2015
    Date of Patent: May 23, 2023
    Assignees: Rush University Medical Center, The Board of Trustees of the University of Illinois
    Inventors: Anna Plaas, Vincent Wang, John Sandy, Rebecca Bell, Jorge Galante, Katie J. Trella
  • Therapeutic Target for Musculoskeletal Inflammation
    Publication number: 20160333410
    Abstract: A method for monitoring a treatment of a subject having a musculoskeletal disorder is provided. The method includes measuring a first expression level of at least two biomarkers at a treatment site prior to the treatment and measuring a second expression level of the at least two biomarkers at the treatment site after the treatment begins. The method further includes comparing the first expression level of the at least two biomarkers prior to the treatment to the second expression level of the at least two biomarkers post treatment and continuing the treatment, altering the treatment or stopping the treatment based on the comparison. A method of treating a musculoskeletal disorder in a subject is also provided. The method includes removing a aggrecan-hyaluronan matrix from a treatment site in the subject.
    Type: Application
    Filed: January 14, 2015
    Publication date: November 17, 2016
    Applicants: RUSH UNIVERSITY MEDICAL CENTER, THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
    Inventors: Anna Plaas, Vincent Wang, John Sandy, Rebecca Bell, Jorge Galante, Katie J. Trella
  • Antibodies, assays and kits to quantitate cartilage destruction
    Publication number: 20070099246
    Abstract: Antibody compositions specific for peptides released during arthritic cartilage destruction are provided as reagents for assay of progression of arthritic processes for antibodies, and as diagnostic and prognostic agents. Also provided are methods and kits for this assay.
    Type: Application
    Filed: November 1, 2006
    Publication date: May 3, 2007
    Inventors: John Sandy, Koichi Masuda, Brian Pfister