Abstract: A process for on-site hydrogen reforming is disclosed. The process includes providing a combined reformer heat exchanger component in which heated air, steam, and hydrocarbon fuel react to form process gas containing hydrogen, and the process gas is cooled via the heat exchanger. The combined components enable reductions in size, materials, costs, and heat loss. Additionally, as the heat exchanger side of the component operates at a cooler temperature, an uninsulated flange for access to the catalyst chamber can be used. A combined combustion heat exchanger component is also provided with similar advantages. Process gas is processed, and hydrogen gas is produced via a purification process.

Abstract: Improved systems, methods, and architectures to enhance decision making in Smart Cities and Smart Regions. A system includes an index structure including a first hierarchical data structure including a first hierarchical score based on a plurality of first-level elements, each of the plurality of first-level elements having a respective weighting, and a second hierarchical data structure including a plurality of second hierarchical scores based on a plurality of second-level elements, each of the plurality of second-level elements having a respective weighting, such that the first hierarchical score is based on the plurality of second hierarchical scores through an index factor; and a computer-implemented regional monitor engine to manage local access to a plurality of external data sources to coordinate writes to the index structure.

Abstract: Improved systems, methods, and architectures to enhance decision making in Smart Cities and Smart Regions. A system includes an index structure including a first hierarchical data structure including a first hierarchical score based on a plurality of first-level elements, each of the plurality of first-level elements having a respective weighting, and a second hierarchical data structure including a plurality of second hierarchical scores based on a plurality of second-level elements, each of the plurality of second-level elements having a respective weighting, such that the first hierarchical score is based on the plurality of second hierarchical scores through an index factor; and a computer-implemented regional monitor engine to manage local access to a plurality of external data sources to coordinate writes to the index structure.

Abstract: Improved systems, methods, and architectures to enhance decision making in Smart Cities and Smart Regions. A system includes an index structure including a first hierarchical data structure including a first hierarchical score based on a plurality of first-level elements, each of the plurality of first-level elements having a respective weighting, and a second hierarchical data structure including a plurality of second hierarchical scores based on a plurality of second-level elements, each of the plurality of second-level elements having a respective weighting, such that the first hierarchical score is based on the plurality of second hierarchical scores through an index factor; and a computer-implemented regional monitor engine to manage local access to a plurality of external data sources to coordinate writes to the index structure.

Abstract: A process for on-site hydrogen reforming is disclosed. The process includes providing a combined reformer heat exchanger component in which heated air, steam, and hydrocarbon fuel react to form process gas containing hydrogen, and the process gas is cooled via the heat exchanger. The combined components enable reductions in size, materials, costs, and heat loss. Additionally, as the heat exchanger side of the component operates at a cooler temperature, an uninsulated flange for access to the catalyst chamber can be used. A combined combustion heat exchanger component is also provided with similar advantages. Process gas is processed, and hydrogen gas is produced via a purification process.

Abstract: A system and method for developing and implementing a workforce virtualization program comprises six phases. A virtualization assessment and profiling process uses analytic methods to determine the feasibility of virtualizing some or all of an organization's workers. A mitigation assessment is conducted to identify cost-effective means of reducing barriers to virtualization. Scenario assessment and modeling phase allows an organization to develop an optimum virtualization scenario. A policy review and development phase allows an organization to develop virtualization policies, including business continuity plans. A virtualization implementation planning phase allows and organization to develop detailed plans for deployment of the virtualization scenario. A monitoring and refinement process allows an organization to track implementation of the deployment plans and modify as necessary.

Abstract: A system and method for developing and implementing a workforce virtualization program comprises six phases. A virtualization assessment and profiling process uses analytic methods to determine the feasibility of virtualizing some or all of an organization's workers. A mitigation assessment is conducted to identify cost-effective means of reducing barriers to virtualization. Scenario assessment and modeling phase allows an organization to develop an optimum virtualization scenario. A policy review and development phase allows an organization to develop virtualization policies, including business continuity plans. A virtualization implementation planning phase allows and organization to develop detailed plans for deployment of the virtualization scenario. A monitoring and refinement process allows an organization to track implementation of the deployment plans and modify as necessary.

Abstract: Improved systems, methods, and architectures to enhance decision making in Smart Cities and Smart Regions. A system includes an index structure including a first hierarchical data structure including a first hierarchical score based on a plurality of first-level elements, each of the plurality of first-level elements having a respective weighting, and a second hierarchical data structure including a plurality of second hierarchical scores based on a plurality of second-level elements, each of the plurality of second-level elements having a respective weighting, such that the first hierarchical score is based on the plurality of second hierarchical scores through an index factor; and a computer-implemented regional monitor engine to manage local access to a plurality of external data sources to coordinate writes to the index structure.

Abstract: A system and method for developing and implementing a workforce virtualization program comprises six phases. A virtualization assessment and profiling process uses analytic methods to determine the feasibility of virtualizing some or all of an organization's workers. A mitigation assessment is conducted to identify cost-effective means of reducing barriers to virtualization. Scenario assessment and modeling phase allows an organization to develop an optimum virtualization scenario. A policy review and development phase allows an organization to develop virtualization policies, including business continuity plans. A virtualization implementation planning phase allows and organization to develop detailed plans for deployment of the virtualization scenario. A monitoring and refinement process allows an organization to track implementation of the deployment plans and modify as necessary.

Abstract: A method for the treatment and/or prophylaxis of conditions characterised by altered bowel function and/or visceral pain in humans or non-human mammals, which method comprises the administration of an effective, non-toxic and pharmaceutically acceptable amount of an NK3 receptor antagonist, wherein the condition characterised by altered bowel function and/or visceral pain is selected from certain irritable bowel syndrome conditions, functional abdominal bloating, functional constipation, functional diarrhea, other bowel conditions and functional abdominal pain.

Abstract: A compound which acts as an antagonist at 5-HT4 receptors is of potential use in the treatment of conditions associated with bladder hypersensitivity, such as urinary incontinence, which is often associated with irritable bowel syndrome (IBS) and a compound which acts as an agonist at 5-HT4 receptors is of potential use in the treatment of conditions associated with a poorly functioning bladder, such as urinary bladder hypoactivity following prostectomy.

Abstract: A compound which acts as an antagonist at 5-HT4 receptors is of potential use in the treatment of conditions associated with bladder hypersensitivity, such as urinary incontinence, which is often associated with irritable bowel syndrome (IBS) and a compound which acts as an agonist at 5-HT4 receptors is of potential use in the treatment of conditions associated with a poorly functioning bladder, such as urinary bladder hypoactivity following prostectomy.

Abstract: The use of orexin receptor antagonists as neuroprotectants, and in the treatment of nausea and vomiting, irritable bowel syndrome and other conditions associated with visceral pain.

Abstract: A compound which acts as an antagonist at 5-HT4 receptors is of potential use in the treatment of conditions associated with bladder hypersensitivity, such as urinary incontinence, which is often associated with irritable bowel syndrome (IBS) and a compound which acts as an agonist at 5-HT4 receptors is of potential use in the treatment of conditions associated with a poorly functioning bladder, such as urinary bladder hypoactivity following prostectomy.

Abstract: The use of KIAA0551 polypeptides and polynucleotides in the design of protocols for the treatment of neuropathies, neuropathic pain, inflammatory and chronic pain, neurodegenerative conditions such as Motor Neuron Disease, Parkinson's Disease, Alzheimer's Disease and other dementias, as well as ischaemic damage in neuronal and cardiac tissues, through disease or infectious agents, among others, and diagnostic assays for such conditions. Also disclosed are methods for producing such polypeptides by recombinant techniques.

Abstract: The use of KIAA0551 polypeptides and polynucleotides in the design of protocols for the treatment of neuropathies, neuropathic pain, inflammatory and chronic pain, neurodegenerative conditions such as Motor Neuron Disease, Parkinson's Disease, Alzheimer's Disease and other dementias, as well as ischaemic damage in neuronal and cardiac tissues, through disease or infectious agents, among others, and diagnostic assays for such conditions. Also disclosed are methods for producing such polypeptides by recombinant techniques.

Abstract: A process and arrangement for contacting a moving bed of compact particulate material, usually catalyst, with a radial flow of fluid maintains an unconfined surface of catalyst particles in place by passing fluid axially into the upper surface of the bed and maintaining radial gas flow across an inlet screen at an elevation that is above the upper most elevation of perforations for withdrawing gas flow from the particulate bed. Two vertical screens confine the bed of catalyst. Perforations cover substantially the entire length of the inlet screen. The outlet portion of the screen has perforations that end below the top of the free surface of the catalyst bed and define an upper bed portion therebetween. The inlet screen directs gas flow radially across the inlet screen into an upper portion of the bed and cause at least partial axial flow of gas through the upper portion of the particle bed.

Abstract: The present invention is directed to a method for the treatment of post-operative nausea and vomiting wherein granisetron is administered to a patient in need thereof.

Abstract: A method of treatment of nausea and vomiting is disclosed which comprises administering to a human or animal subject granisetron and an antiemetic corticosteroid.