Abstract: The invention relates to a novel multiwell array comprising a plurality of wells, the majority of which have a unique cross-sectional shape whereby each well within the array can be identified and so tracked whilst the contents of the array are investigated. The invention also concerns a computer and a programmable data storage device for use with the array and an imaging apparatus including any one or more of the afore features or aspects.

Abstract: We describe a circularly permuted growth hormone polypeptide antagonist; compositions comprising said antagonist and methods to treat conditions that would benefit from administration of said antagonist.

Abstract: A method of operating a vehicle is described, in which the vehicle includes a frame structure carrying a ground engaging structure whereby the vehicle may travel over the ground, the ground engaging structure including a pair of steerable wheels which with the vehicle travelling in a travelling direction, are front wheels, and a pair of rear wheels which may each independently be braked by the operation of respective brake devices, the vehicle further including a controller which is capable of providing signals independently to the brake devices of the rear wheels to effect application and release of a selected brake, and the method including sensing the vehicle travelling speed and providing a first input to the controller, sensing steering of the vehicle by the operator and providing a second input to the controller, and where the travelling speed is below a threshold speed, and depending on the direction of steering of the vehicle, the controller applying one of the brakes.

Abstract: The invention relates to chimeric polypeptides wherein said polypeptides comprise a modified binding domain of growth hormone linked to a receptor binding domain of growth hormone receptor; and tandems/oligomers of said modified growth hormone binding domains.

Abstract: A hydraulic lift device for an attaching device of a tractor which has a hydraulic pressure supply device and a hydraulic tank, comprising for each of two lower steering arms, a double acting hydraulic cylinder having a cylinder housing, a piston rod, a piston with a piston-end piston area and a piston rod-end piston area, as well as a piston-end cylinder chamber and a piston rod-end cylinder chamber. The device further comprises a first switching valve, which has at least three switching positions and four ports. The first port represents a connection to the pressure supply device. The second port represents the connection to the hydraulic tank. The third port represents the connection to the piston-end cylinder chamber of the first hydraulic cylinder and the fourth port represents the connection to the piston rod-end cylinder chamber of the second hydraulic chamber.

Abstract: The invention relates to a hydraulic lift device for an attaching device of a tractor which has a hydraulic pressure supply device and a hydraulic tank, comprising for each of two lower steering arms, a double acting hydraulic cylinder having a cylinder housing, a piston rod, a piston with a piston-end piston area and a piston rod-end piston area, as well as a piston-end cylinder chamber and a piston rod-end cylinder chamber. The device further comprises a first switching valve, which has at least three switching positions and four ports. The first port represents a connection to the pressure supply device. The second port represents the connection to the hydraulic tank. The third port represents the connection to the piston-end cylinder chamber of the first hydraulic cylinder and the fourth port represents the connection to the piston rod-end cylinder chamber of the second hydraulic chamber.

Abstract: An assembly with a lower steering arm has a strut 1 and an attaching end 16. To achieve a cost-effective design while at the same time reducing the play between the attaching end 16 and the end of the strut 1 received therein, the attaching end 16 includes a base member 18 and a cover 19. A blocking pawl 34 is supported in the base member 18. The cover 19 is welded to the base member 18 and comprises a stop face 30 for the end face 10 of the strut 1. Thus, any tolerances in the region of the base member 18 provided in the form of a forging do not affect the position of the stop face 30. The latter can be aligned when connecting the base member 18 and the cover 19. Because of its setting contour, the actuating lever 43 can be used for both the right hand and the left hand lower steering arm.

Abstract: An assembly with a lower steering arm has a strut 1 and an attaching end 16. The attaching end 16 includes a base member 18 and a cover 19. A blocking pawl 34 is supported in the base member 18. The cover 19 is welded to the base member 18. The cover 19 includes a stop face 30 for the end face 10 of the strut 1. Thus, any tolerances in the region of the base member 18 provided in the form of a forging do not affect the position of the stop face 30. The latter can be aligned when connecting the base member 18 and the cover 19. Because of its setting contour, an actuating lever 43 can be used for both the right hand and the left hand lower steering arm.

Abstract: A method of producing a welded assembly comprising two members and wherein the assembly is adapted subsequently to have an element connected thereto in a manner that imparts a connection force to the welded connection between the two members and the method comprising the steps of, prior to welding the two members together, temporarily applying a force to at least one of the two members to simulate the force which is to be imparted to the welded connection between the two members as a result of the connection of the further element to the assembly, welding the two members together to form the assembly while maintaining the predetermined force on the at least one member and subsequently removing the predetermined force from the at least one member.

Abstract: A manually adjustable wheel for a vehicle e.g.

Abstract: The spacer (2) is for use in spacing a disc from attachment portions of the rim of the wheel. The spacer comprises two spacing portions (4,6) and a rigid joining portion (22) retaining the spacing portions at a constant distance and orientation with respect to each other. The spacing portions (4,6) each have a bolt-receiving passage (24) and bearing surfaces (8,10) extending around the mouths of the passage. The bearing surfaces (8,10) of each spacing portion are in parallel planes which are the same planes for both spacing portions.