Patents by Inventor John Schetz

John Schetz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DRUG REPURPOSING FOR DELAYED TREATMENT OF ISCHEMIC STROKE
    Publication number: 20250134902
    Abstract: A method for treating ischemic injury in a subject having an ischemic injury is disclosed. The method can include administering to the subject a composition comprising an effective amount of a Sigma receptor agonist to treat the ischemic injury in the subject. The composition can be administered at least about 6 hours after occurrence of the ischemic injury, and administration of the composition can stimulate release of brain-derived neurotropic factor from neurons and/or to reduce one or more neurological deficits and/or symptoms.
    Type: Application
    Filed: February 9, 2023
    Publication date: May 1, 2025
    Inventors: Derek SCHREIHOFER, John Schetz
  • Butyrophenones and sigma-1 receptor antagonists protect against oxidative-stress
    Publication number: 20060106064
    Abstract: The present invention includes compositions and methods for the protection of one or more central nervous system cells from trauma, when administered before, during or after the trauma, wherein the composition includes an effective amount of a butyrophenone, e.g., a 1-linked phenyl butyrophenone that is electronegative along the butyl chain and/or a Sigma-1 receptor antagonist.
    Type: Application
    Filed: November 3, 2005
    Publication date: May 18, 2006
    Applicant: University of North Texas Health Science Center at Fort Worth
    Inventors: John Schetz, James Simpkins, Jeffery Talbert