Abstract: Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N,-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation. This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.

Abstract: The present invention concerns compositions that comprise alcohol-free microemulsions and methods for their use that include a surfactant, a lipophilic linker, and/or a hydrophilic linker. These compositions can be used, for example, in cosmetic or hair applications. In certain aspects, compositions of the invention have the ability to microemulsify sebum while providing enhanced cleansing of cosmetic products from the skin or hair. In addition, the compositions have the ability to enhance the penetration of skin or hair active ingredients, such as emollients, humectants, anti-oxidants, lipids, vitamins, botanicals, dyes, tanning compounds, etc.

Abstract: The present invention relates to novel methods and compositions comprising key metabolic ingredients for treating aged, mature, nutritionally-compromised, or environmentally-damaged skin. These methods and compositions provide improvements in the skin's visual appearance, physiological functions, clinical properties, and biophysical properties.