Abstract: The present invention relates to compositions comprising an alpha-adrenoceptor ligand for use in the treatment of benign anorectal conditions, in particular haemorrhoids. In addition to an alpha-adrenoceptor ligand, the compositions of the inventions may additionally include a calcium channel activator. Compositions with guanfacine and S(?)BayK8644 are preferred.

Abstract: A liquid metering unit comprising a conduit of flexible material depending between first and second rotatable rollers, each having first and second curved surfaces and first and second flat portions. The rollers are driven in opposite directions so that their first curved surfaces impinge upon the conduit, constricting it and causing it to move upwards along its longitudinal axis such that any liquid contained therein is expelled from its lower end. Continued rotation of the rollers presents the second flat portions to the conduit, which is released and drops back to its original position. The conduit is recharged with liquid from a reservoir connected to its upper end by means of a vacuum source selectively connectable to its lower end.

Abstract: A sample processing unit is disclosed for use in the a method of analysis, particularly autoanalysis, wherein the sample is presented for examination by deposition upon a tape substrate.

Abstract: A rapid method of staining microorganisms with fluorochrome dyes to render them readily visible when illuminated with U.V. radiation and viewed under a microscope is described. The method involves chemical treatment of a sample containing microorganisms suspended in a liquid medium with phosphate ions to modify (chemically) the dye-receptor sites in the microorganisms and then staining the treated microorganisms with a fluorochrome dye. Suitable additional treatments which enhance fluorescence are also possible, including methylation, esterification, hydrolysis, oxidation and treatment with sulphur dioxide. The method is particularly advantageous in the microscopic enumeration of microorganisms. Also certain techniques are described which permit the determination of viable and non-viable cells.