Patents by Inventor John Senger
John Senger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11964374Abstract: A stapler including a moveable strike plate and accessibility features is described. A slidable strike plate is moveable from a first staple forming position to a second staple forming position to form different staple shapes. The slidable strike plate is moved relative to the anvil of the stapler with a single hand to change positions. A rotatable strike plate is turned with a single hand to move between staple forming positions by rotating an outer dial of the rotatable strike plate relative to the anvil of the stapler. The stapler includes an indicator window that shows if the stapler is empty or running low on staples and a quick release staple loading magazine that is operable using a single hand.Type: GrantFiled: November 9, 2022Date of Patent: April 23, 2024Assignee: WORKLIFE BRANDS LLCInventors: Robert Fish, Marc Senger, Michael McDuffee, Ben Beck, John Swain, Nicole Nassif
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Patent number: 11959858Abstract: Chronic Kidney Disease (CKD) is characterized by the progressive loss of renal function which eventually leads to End Stage Renal Disease (ESRD). CKD affects roughly 30 million Americans, costs billions of dollars in healthcare spending annually, and leaves thousands of patients reliant on burdensome dialysis treatments while waiting for a transplant. Fortunately, CKD may be controllable if diagnosed early in the disease progression. RAMETRIX™ is a novel public health screening technology for early diagnosis and detection of CKD. This technology uses Raman spectroscopy and chemometrics to analyze the molecular composition of urine and other biological fluids. RAMETRIX™ is a fast, non-invasive, accurate, and inexpensive diagnostic tool that can revolutionize the way healthcare providers detect and treat CKD. The RAMETRIX™ AutoScanner is a system enabling more efficient sample processing in large-scale settings such as hospitals and medical laboratories.Type: GrantFiled: June 11, 2021Date of Patent: April 16, 2024Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: John L. Robertson, Ryan Senger
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Patent number: 11821687Abstract: Disclosed are systems and methods for aseptically filling pharmaceutical containers with a pharmaceutical substance and then lyophilizing it. In one general aspect, the system and method can employ a lyophilizer loader subsystem having an interior chamber in communication with an interior chamber of a lyophilizer subsystem via a portal with a sealable door, with the collective interior being aseptically sealable. An articulated robotic arm can be employed to batch transfer to the lyophilizer subsystem container nests bearing the pharmaceutical containers. In one embodiment, the nests may be transferred serially to the loader subsystem, with the articulated robotic arm being configured to transfer the nests of containers in batches to the lyophilizer subsystem. The articulated robotic arm can also be configured to be used to move batches of nests within the lyophilizer subsystem. One implementation includes two articulated arms and a joint rotary wrist driven by two rotary shoulders.Type: GrantFiled: June 18, 2021Date of Patent: November 21, 2023Assignee: VANRX PHARMASYSTEMS INC.Inventors: Christopher Procyshyn, John Senger, Juvenal Naing
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Publication number: 20230242285Abstract: The system of the invention involves a gloveless aseptic processing system. The automated system is for filling nested pharmaceutical containers with a pharmaceutical fluid substance. A closed sterilizable gloveless isolator chamber is capable of maintaining an aseptic condition, having a sterilization system. The container filling system has a dispensing head for filling the containers, and a container closing system disposed within the gloveless isolator chamber with rams for pushing closures into openings of the nested containers. The container manipulation mechanism is disposed within the gloveless isolator chamber and is capable of positioning the nested pharmaceutical containers within the gloveless isolator chamber including operably disposing the nested pharmaceutical containers with the container filling system and the container closing system. Container tubs sealed by removable covers and contain a container nest bearing a plurality of pre-sterilized pharmaceutical containers.Type: ApplicationFiled: January 31, 2022Publication date: August 3, 2023Inventors: Juvenal NAING, Yakov GOFMAN, Marcin CICHY, John SENGER, Craig RATHE, Carlos Alberto DIAZ GUERRERO
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Patent number: 11554886Abstract: Systems and methods for aseptically filling pharmaceutical containers with pharmaceutical fluid are disclosed. In one general aspect, these are based on an aseptically sealable chamber that includes a transfer wall to which pre-sealed pharmaceutical source and receiving containers are mounted aseptically. A robotic arm and a syringe store are disposed within the chamber along with a sterilizing facility for establishing in the chamber an aseptic condition. The robotic arm can grip and operate syringes to inject and/or extract pharmaceutical products from the containers by piercing their closures with the needles of the syringes.Type: GrantFiled: August 31, 2020Date of Patent: January 17, 2023Assignee: VANRX PHARMASYSTEMS INC.Inventors: Christopher A. Procyshyn, Juvenal Naing, John Senger, Marcin Czeslaw Cichy
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Publication number: 20210310735Abstract: Disclosed are systems and methods for aseptically filling pharmaceutical containers with a pharmaceutical substance and then lyophilizing it. In one general aspect, the system and method can employ a lyophilizer loader subsystem having an interior chamber in communication with an interior chamber of a lyophilizer subsystem via a portal with a sealable door, with the collective interior being aseptically sealable. An articulated robotic arm can be employed to batch transfer to the lyophilizer subsystem container nests bearing the pharmaceutical containers. In one embodiment, the nests may be transferred serially to the loader subsystem, with the articulated robotic arm being configured to transfer the nests of containers in batches to the lyophilizer subsystem. The articulated robotic arm can also be configured to be used to move batches of nests within the lyophilizer subsystem. One implementation includes two articulated arms and a joint rotary wrist driven by two rotary shoulders.Type: ApplicationFiled: June 18, 2021Publication date: October 7, 2021Inventors: Christopher PROCYSHYN, John SENGER, Juvenal NAING
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Patent number: 11047622Abstract: Disclosed are systems and methods for aseptically filling pharmaceutical containers with a pharmaceutical substance and then lyophilizing it. In one general aspect, the system and method can employ a lyophilizer loader subsystem having an interior chamber in communication with an interior chamber of a lyophilizer subsystem via a portal with a sealable door, with the collective interior being aseptically sealable. An articulated robotic arm can be employed to batch transfer to the lyophilizer subsystem container nests bearing the pharmaceutical containers. In one embodiment, the nests may be transferred serially to the loader subsystem, with the articulated robotic arm being configured to transfer the nests of containers in batches to the lyophilizer subsystem. The articulated robotic arm can also be configured to be used to move batches of nests within the lyophilizer subsystem. One implementation includes two articulated arms and a joint rotary wrist driven by two rotary shoulders.Type: GrantFiled: March 25, 2019Date of Patent: June 29, 2021Assignee: VANRX PHARMASYSTEMS INC.Inventors: Christopher Procyshyn, John Senger, Juvenal Naing
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Patent number: 10967994Abstract: Systems and methods for aseptically filling pharmaceutical containers with pharmaceutical fluid are disclosed. In one general aspect, these are based on an aseptically sealable chamber that includes a transfer wall to which pre-sealed pharmaceutical source and receiving containers are mounted aseptically. A robotic arm and a syringe store are disposed within the chamber along with a sterilizing facility for establishing in the chamber an aseptic condition. The robotic arm can grip and operate syringes to inject and/or extract pharmaceutical products from the containers by piercing their closures with the needles of the syringes.Type: GrantFiled: June 4, 2019Date of Patent: April 6, 2021Assignee: VANRX PHARMASYSTEMS INC.Inventors: Christopher A. Procyshyn, Juvenal Naing, John Senger, Marcin Czeslaw Cichy
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Publication number: 20210070481Abstract: Systems and methods for aseptically filling pharmaceutical containers with pharmaceutical fluid are disclosed. In one general aspect, these are based on an aseptically sealable chamber that includes a transfer wall to which pre-sealed pharmaceutical source and receiving containers are mounted aseptically. A robotic arm and a syringe store are disposed within the chamber along with a sterilizing facility for establishing in the chamber an aseptic condition. The robotic arm can grip and operate syringes to inject and/or extract pharmaceutical products from the containers by piercing their closures with the needles of the syringes.Type: ApplicationFiled: August 31, 2020Publication date: March 11, 2021Inventors: Christopher A. PROCYSHYN, Juvenal NAING, John SENGER, Marcin Czeslaw CICHY
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Patent number: 10850873Abstract: Systems and methods for aseptically filling pharmaceutical containers with pharmaceutical fluid are disclosed. In one general aspect, these are based on an aseptically sealable chamber that includes a transfer wall to which pre-sealed pharmaceutical source and receiving containers are mounted aseptically. A robotic arm and a syringe store are disposed within the chamber along with a sterilizing facility for establishing in the chamber an aseptic condition. The robotic arm can grip and operate syringes to inject and/or extract pharmaceutical products from the containers by piercing their closures with the needles of the syringes.Type: GrantFiled: March 8, 2017Date of Patent: December 1, 2020Assignee: VANRX PHARMASYSTEMS INC.Inventors: Christopher Procyshyn, Juvenal Naing, John Senger, Marcin Cichy
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Patent number: 10788264Abstract: Disclosed are systems and methods for aseptically filling pharmaceutical containers with a pharmaceutical substance and then lyophilizing it. In one general aspect, the system and method can employ a lyophilizer loader subsystem having an interior chamber in communication with an interior chamber of a lyophilizer subsystem via a portal with a sealable door, with the collective interior being aseptically sealable. An articulated robotic arm can be employed to batch transfer to the lyophilizer subsystem container nests bearing the pharmaceutical containers. In one embodiment, the nests may be transferred serially to the loader subsystem, with the articulated robotic arm being configured to transfer the nests of containers in batches to the lyophilizer subsystem. The articulated robotic arm can also be configured to be used to move batches of nests within the lyophilizer subsystem. One implementation includes two articulated arms and a joint rotary wrist driven by two rotary shoulders.Type: GrantFiled: April 12, 2016Date of Patent: September 29, 2020Assignee: VANRX PHARMASYSTEMS, INC.Inventors: Christopher Procyshyn, John Senger, Juvenal Naing
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Publication number: 20200156812Abstract: Systems and methods for aseptically filling pharmaceutical containers with pharmaceutical fluid are disclosed. In one general aspect, these are based on an aseptically sealable chamber that includes a transfer wall to which pre-sealed pharmaceutical source and receiving containers are mounted aseptically. A robotic arm and a syringe store are disposed within the chamber along with a sterilizing facility for establishing in the chamber an aseptic condition. The robotic arm can grip and operate syringes to inject and/or extract pharmaceutical products from the containers by piercing their closures with the needles of the syringes.Type: ApplicationFiled: June 4, 2019Publication date: May 21, 2020Inventors: Christopher A. PROCYSHYN, Juvenal NAING, John SENGER, Marcin Czeslaw CICHY
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Publication number: 20200088467Abstract: Disclosed are systems and methods for aseptically filling pharmaceutical containers with a pharmaceutical substance and then lyophilizing it. In one general aspect, the system and method can employ a lyophilizer loader subsystem having an interior chamber in communication with an interior chamber of a lyophilizer subsystem via a portal with a sealable door, with the collective interior being aseptically sealable. An articulated robotic arm can be employed to batch transfer to the lyophilizer subsystem container nests bearing the pharmaceutical containers. In one embodiment, the nests may be transferred serially to the loader subsystem, with the articulated robotic arm being configured to transfer the nests of containers in batches to the lyophilizer subsystem. The articulated robotic arm can also be configured to be used to move batches of nests within the lyophilizer subsystem. One implementation includes two articulated arms and a joint rotary wrist driven by two rotary shoulders.Type: ApplicationFiled: March 25, 2019Publication date: March 19, 2020Applicant: Vanrx Pharamasystems, Inc.Inventors: Christopher PROCYSHYN, John SENGER, Juvenal NAING
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Patent number: 10524980Abstract: A reconfigurable nest handling system for handling nests of objects arranged in a predetermined pattern is presented and applied to a system for filling nested pharmaceutical containers with a pharmaceutical fluid. In one general aspect, the system comprises a sterilizable chamber containing a planar rotary stage with tub and nest positioning systems that may be reconfigurable for holding differently sized pharmaceutical container tubs and nests and pharmaceutical closure tubs and nests. The chamber has a rotatable cover removal station, a rotatable filling station with a dispenser head, and camera guided vacuum pickup facilities for handling container and closure nests. The vacuum pickup facilities may be reconfigurable for handling differently sized nests. An associated method for filling the containers comprises establishing an aseptic condition within the chamber; removing covers from a container tub and a container closure tub by operating both the rotary stage and the cover removal station.Type: GrantFiled: March 21, 2017Date of Patent: January 7, 2020Assignee: Vanrx Pharmasystems, Inc.Inventors: Juvenal Naing, Yakov Gofman, Marcin Cichy, John Senger, Craig Rathe
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Publication number: 20180071168Abstract: A reconfigurable nest handling system for handling nests of objects arranged in a predetermined pattern is presented and applied to a system for filling nested pharmaceutical containers with a pharmaceutical fluid. In one general aspect, the system comprises a sterilizable chamber containing a planar rotary stage with tub and nest positioning systems that may be reconfigurable for holding differently sized pharmaceutical container tubs and nests and pharmaceutical closure tubs and nests. The chamber has a rotatable cover removal station, a rotatable filling station with a dispenser head, and camera guided vacuum pickup facilities for handling container and closure nests. The vacuum pickup facilities may be reconfigurable for handling differently sized nests. An associated method for filling the containers comprises establishing an aseptic condition within the chamber; removing covers from a container tub and a container closure tub by operating both the rotary stage and the cover removal station.Type: ApplicationFiled: March 21, 2017Publication date: March 15, 2018Inventors: Juvenal Naing, Yakov Gofman, Marcin Cichy, John Senger, Craig Rathe
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Publication number: 20180037343Abstract: Systems and methods for aseptically filling pharmaceutical containers with pharmaceutical fluid are disclosed. In one general aspect, these are based on an aseptically sealable chamber that includes a transfer wall to which pre-sealed pharmaceutical source and receiving containers are mounted aseptically. A robotic arm and a syringe store are disposed within the chamber along with a sterilizing facility for establishing in the chamber an aseptic condition. The robotic arm can grip and operate syringes to inject and/or extract pharmaceutical products from the containers by piercing their closures with the needles of the syringes.Type: ApplicationFiled: March 8, 2017Publication date: February 8, 2018Inventors: Christopher Procyshyn, Juvenal Naing, John Senger, Marcin Cichy
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Publication number: 20170291774Abstract: Disclosed are systems and methods for aseptically filling pharmaceutical containers with a pharmaceutical substance and then lyophilizing it. In one general aspect, the system and method can employ a lyophilizer loader subsystem having an interior chamber in communication with an interior chamber of a lyophilizer subsystem via a portal with a sealable door, with the collective interior being aseptically sealable. An articulated robotic arm can be employed to batch transfer to the lyophilizer subsystem container nests bearing the pharmaceutical containers. In one embodiment, the nests may be transferred serially to the loader subsystem, with the articulated robotic arm being configured to transfer the nests of containers in batches to the lyophilizer subsystem. The articulated robotic arm can also be configured to be used to move batches of nests within the lyophilizer subsystem. One implementation includes two articulated arms and a joint rotary wrist driven by two rotary shoulders.Type: ApplicationFiled: April 12, 2016Publication date: October 12, 2017Inventors: Christopher Procyshyn, John Senger, Juvenal Naing
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Patent number: 9746008Abstract: Examples of a pressure wave generator configured to generate high energy pressure waves in a medium are disclosed. The pressure wave generator can include a movable piston with a guide through which a piston control rod can move or slide. The pressure wave generator can include a transducer coupled to a medium. During an impact of the piston on the transducer, the control rod can slide in the guide, which can reduce stress on the rod. The pressure wave generator can include a damper to decelerate the control rod, independently of the piston. Impact of the piston on the transducer transfers a portion of the piston's kinetic energy into the medium thereby generating pressure waves in the medium. A piston driving system may be used to provide precise and controlled launching or movement of the piston. Examples of methods of operating the pressure wave generator are disclosed.Type: GrantFiled: November 4, 2014Date of Patent: August 29, 2017Assignee: General Fusion Inc.Inventors: Lon McIlwraith, John Senger, Darcy Montgomery, Douglas H. Richardson, Peter Kostka, Kristin Bell, Ryan Zindler, Michel Georges Laberge
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Patent number: 9386909Abstract: An applicator suitable for converting a white-light endoscope into an endoscope for combined white-light/fluorescence imaging is disclosed. The applicator facilitates attachment of an optical element, for example an optical filter, to a distal optical port of an endoscope. The applicator engages with alignment feature on the endoscope's distal end and releasably supports the optical element in an opening that is aligned with the optical port. The optical element is released in a proximal direction by pressing down on an actuator.Type: GrantFiled: March 29, 2013Date of Patent: July 12, 2016Assignee: Novadaq Technologies Inc.Inventors: John Fengler, John Senger, Gary Jenne
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Publication number: 20150152899Abstract: Examples of a pressure wave generator configured to generate high energy pressure waves in a medium are disclosed. The pressure wave generator can include a movable piston with a guide through which a piston control rod can move or slide. The pressure wave generator can include a transducer coupled to a medium. During an impact of the piston on the transducer, the control rod can slide in the guide, which can reduce stress on the rod. The pressure wave generator can include a damper to decelerate the control rod, independently of the piston. Impact of the piston on the transducer transfers a portion of the piston's kinetic energy into the medium thereby generating pressure waves in the medium. A piston driving system may be used to provide precise and controlled launching or movement of the piston. Examples of methods of operating the pressure wave generator are disclosed.Type: ApplicationFiled: November 4, 2014Publication date: June 4, 2015Inventors: Lon McIlwraith, John Senger, Darcy Montgomery, Douglas H. Richardson, Peter Kostka, Kristin Bell, Ryan Zindler, Michel Georges Laberge