Abstract: A pressure control ventilation system (10) configured to provide airway release ventilation synchronous with a breathing subject that includes a pressure generator (12) configured to generate pressurized flow of breathable gas to a subject, one or more sensors (28) configured to generate output signals conveying information related to one or more gas parameters of the pressurized flow, one or more processors (14) configured to execute computer modules comprising: a synchronization module (16) configured to detect inspiratory (39, 45) and expiratory (40, 44, 59) flow phases of the subject based at least on the signals; an interval module (18) configured to define time intervals (54, 60); a control module (20) configured to control the generator to deliver flow fluctuating between a first pressure range (48) to maintain adequate lung volume and a second pressure range (50) to facilitate C02 exhalation, the control including: delivering the flow in the first range at the beginning (56) of a first time interval (

Abstract: A method of manufacturing an implantable electronic device, including: providing a silicon wafer; building a plurality of layers coupled to the wafer including an oxide layer coupled to the silicon wafer; a first reactive parylene layer coupled to the oxide layer, an electrode layer coupled to the first reactive parylene layer, and a second reactive parylene layer, coupled to the electrode layer, that chemically bonds to the first reactive polymer layer, and a second polymer layer coupled to the second reactive parylene layer; coating the plurality of layers with an encapsulation, and modifying the encapsulation and at least one of the plurality of layers to expose an electrode site in the electrode layer.

Abstract: The neural interface system of one embodiment includes a cylindrical shaft, a lateral extension longitudinally coupled to at least a portion of the shaft and having a thickness less than a diameter of the shaft, and an electrode array arranged on the lateral extension and radially offset from the shaft, including electrode sites that electrically interface with their surroundings. The method of one embodiment for making the neural interface system includes forming a planar polymer substrate with at least one metallization layer, patterning on at least one metallization layer an electrode array on a first end of the substrate, patterning conductive traces on at least one metallization layer, rolling a portion of the substrate toward the first end of the substrate, and securing the rolled substrate into a shaft having the first end of the substrate laterally extending from the shaft and the electrode array radially offset from the shaft.

Abstract: An apparatus comprises a flexible substrate. The flexible substrate includes a first substrate surface, a surface electrode array that includes a plurality of electrodes disposed on the first substrate surface, one or more flexible neural probes substantially orthogonal to the first substrate surface and insertable into biological tissue, and a penetrating electrode array that includes a plurality of electrodes formed on the one or more flexible neural probes, wherein electrodes of the surface electrode array and the penetrating electrode array are configured to one or both of receive a neural signal from a neural signal source and provide electrical stimulation energy to a neural stimulation target.

Abstract: A method of manufacturing an implantable electronic device, including: providing a silicon wafer; building a plurality of layers coupled to the wafer including an oxide layer coupled to the silicon wafer; a first reactive parylene layer coupled to the oxide layer, an electrode layer coupled to the first reactive parylene layer, and a second reactive parylene layer, coupled to the electrode layer, that chemically bonds to the first reactive polymer layer, and a second polymer layer coupled to the second reactive parylene layer; coating the plurality of layers with an encapsulation, and modifying the encapsulation and at least one of the plurality of layers to expose an electrode site in the electrode layer.

Abstract: A method of manufacturing an implantable electronic device, including: providing a silicon wafer; building a plurality of layers coupled to the wafer including an oxide layer coupled to the silicon wafer; a first reactive parylene layer coupled to the oxide layer, an electrode layer coupled to the first reactive parylene layer, and a second reactive parylene layer, coupled to the electrode layer, that chemically bonds to the first reactive polymer layer, and a second polymer layer coupled to the second reactive parylene layer; coating the plurality of layers with an encapsulation, and modifying the encapsulation and at least one of the plurality of layers to expose an electrode site in the electrode layer.

Abstract: An apparatus comprises a tubular body having a lumen and a distal region, a plurality of ports at the distal region of the tubular body, and a plurality of independently gatable microvalves disposed at the plurality of ports. A port extends from internal to the lumen to outside the tubular body, and a gatable microvalve is controllable by a stimulus to provide and prevent fluidic transfer through the ports.

Abstract: The neural interface system of one embodiment includes a cylindrical shaft, a lateral extension longitudinally coupled to at least a portion of the shaft and having a thickness less than a diameter of the shaft, and an electrode array arranged on the lateral extension and radially offset from the shaft, including electrode sites that electrically interface with their surroundings. The method of one embodiment for making the neural interface system includes forming a planar polymer substrate with at least one metallization layer, patterning on at least one metallization layer an electrode array on a first end of the substrate, patterning conductive traces on at least one metallization layer, rolling a portion of the substrate toward the first end of the substrate, and securing the rolled substrate into a shaft having the first end of the substrate laterally extending from the shaft and the electrode array radially offset from the shaft.

Abstract: An apparatus comprises a flexible substrate. The flexible substrate includes a first substrate surface, a surface electrode array that includes a plurality of electrodes disposed on the first substrate surface, one or more flexible neural probes substantially orthogonal to the first substrate surface and insertable into biological tissue, and a penetrating electrode array that includes a plurality of electrodes formed on the one or more flexible neural probes, wherein electrodes of the surface electrode array and the penetrating electrode array are configured to one or both of receive a neural signal from a neural signal source and provide electrical stimulation energy to a neural stimulation target.

Abstract: A nozzle in which an airfoil includes a pressure surface and a suction surface that join at substantially opposing chordal ends of the airfoil to form a leading edge of the airfoil and a trailing edge of the airfoil. A trailing edge passage is defined through the airfoil through which coolant flows. The trailing edge passage is proximate to the trailing edge of the airfoil and has a contoured shape that conforms to that of the trailing edge.

Abstract: A method of manufacturing an implantable electronic device, including: providing a silicon wafer; building a plurality of layers coupled to the wafer including an oxide layer coupled to the silicon wafer; a first reactive parylene layer coupled to the oxide layer, an electrode layer coupled to the first reactive parylene layer, and a second reactive parylene layer, coupled to the electrode layer, that chemically bonds to the first reactive polymer layer, and a second polymer layer coupled to the second reactive parylene layer; coating the plurality of layers with an encapsulation, and modifying the encapsulation and at least one of the plurality of layers to expose an electrode site in the electrode layer.

Abstract: A cryogenic detector is used for detection in a biological assay.

Abstract: A nozzle in which an airfoil includes a pressure surface and a suction surface that join at substantially opposing chordal ends of the airfoil to form a leading edge of the airfoil and a trailing edge of the airfoil. A trailing edge passage is defined through the airfoil through which coolant flows. The trailing edge passage is proximate to the trailing edge of the airfoil and has a contoured shape that conforms to that of the trailing edge.

Abstract: A cryogenic detector is used for detection in a biological assay.

Abstract: A web inspection module is described for scanning an imprinted web in a printing press. The web inspection module includes a light source for illuminating a portion of the web, a contact image sensor having a plurality of sensing elements, and a processor for receiving and processing image data representative of the imprinted web.

Abstract: An assembly and method for image data acquisition is provided for obtaining image data representative of a printed work on a moving web in a printing press. The assembly includes a light source for illuminating the web, an optical fiber taper for minifying an image from a first end to a second end of the taper, wherein the first end of the taper is in optical communication with the printed work on the web, a sensor coupled to the second end of the taper, and a processor for receiving image data representative of the printed work from the sensor.

Abstract: An illumination system for a web travelling from upstream to downstream in a longitudinal direction in a printing press is described. The illumination system includes a first and a second illuminator for emitting light, each illuminator having a long axis arranged in a lateral direction. Further, the system includes a first and a second reflector, with the second reflector being arranged downstream from the first reflector. Each reflector has a surface for reflecting light from a corresponding illuminator toward the web, wherein a cross-section of each reflecting surface is a portion of a parabola having a focal point, or a portion of an ellipse, having two focal points. An illuminator is located at a corresponding focal point.

Abstract: A cooling circuit is provided within a turbine nozzle to help increase turbine efficiency. The turbine nozzle includes first, second and third cavities, an outer band, and an inner band. The cooling circuit contains an inlet receiving cooling medium flow, and a first duct insert disposed in the second cavity. The first duct insert receives the cooling medium flow via the inlet and duct flows the cooling medium flow to a bottom of the second cavity. An impingement insert is disposed in the first cavity that receives the cooling medium flow from the first duct insert. A first impingement plate is disposed within the outer band defining an outer band cooling path within the outer band. The outer band cooling path receives the cooling medium flow from the first cavity. A second cavity cooling path is defined between the first duct insert and a second cavity wall, where the second cavity cooling path receives the cooling medium flow from the outer band cooling path.

Abstract: The present invention provides an improved engine for aeronautical applications which includes a core engine block having a drive shaft rotatably mounted within the core engine block and a motive device for rotating the drive shaft. A propeller speed reduction unit is connected to the drive shaft for transferring power from the drive shaft to a propeller and an accessory drive gearbox is connected to the drive shaft for transferring power from the drive shaft to at least one accessory device. The accessory drive gearbox includes an accessory drive crank gear connected to the drive shaft and a drive gear intermeshing with the crank gear. Finally, at least two inter-module dampers are mounted in the engine, one each of the inter-module dampers positioned between the core engine block and the accessory drive gearbox and the core engine block and the propeller speed reduction unit to dampen and isolate vibrations.