Abstract: Disclosed herein are compounds and methods for inhibiting Aha1 for the treatment of tauopathies and neurodegenerative diseases. The Aha1 inhibitor may reduce the interaction between Aha1 and Hsp90. The Aha1 inhibitor may reduce aggregation of tau protein. The Aha1 inhibitor may include a compound selected from KU-177, KU-174, and KU-308.

Abstract: Provided is an umbrella mount adapted for operational engagement with an associated truck bed stake pocket. The umbrella mount comprises an insert mount, a tube insert, and a holding mechanism. The insert mount may be adapted for operational engagement within the truck bed stake pocket. The tube insert may be of lesser diameter than an associated umbrella post. The holding mechanism may be adapted to hold the umbrella post securely within the tube insert.

Abstract: A system for predicting an anomalous request comprises a processor associated with a server. The processor is configured to generate a first set of data objects associated with a first user profile. The processor is configured to compare the first set of the data objects to approved data and audit data to generate a second set of data objects with a set of anomalous data indicators for the first user profile. The processor is further configured to process the second set of the data objects through an anomaly learning model to determine a predictive degree of approval associated with the user profile. The processor is further configured to determine to how to process the user profile based on the predictive degree of approval. The processor is further configured to assign a profile indicator to the user profile.

Abstract: A vehicle includes a primary axle powered by an actuator and a secondary axle powered by a motor and including a wheel and a clutch selectively coupling the wheel to the motor via mating components. A controller is electrically connected to the clutch and the motor. The controller is programmed to, in response to an engagement of the clutch being unsuccessful within a first duration of time, command a series of speeds to the motor based on wheel speed and an alternating offset that changes between positive and negative signs at predefined periods so that relative speeds between the mating components oscillate due to the alternating offset to jiggle the clutch into engagement.

Abstract: A system for predicting an anomalous request comprises a processor associated with a server. The processor is configured to parse a user profile from a plurality of user profiles to generate a first set of data objects associated with the first user profile. The processor is configured to compare the first set of the data objects to approved data and audit data to generate a second set of data objects with a set of anomalous data indicators for the first user profile. The processor is further configured to process the second set of the data objects through an anomaly learning model to determine a predictive degree of approval associated with the user profile. The processor is further configured to determine to approve, flag or disapprove the user profile based on the predictive degree of approval. The processor is further configured to assign a profile indicator to the user profile.

Abstract: Methods and systems for receiving a detection of a physical presence of a user and, in response, initiating a start-up process on an enterprise device according to a profile associated with the user are described. Thereafter, the system receives authentication credentials at the enterprise device and the user is granted access to the enterprise device after the authentication credentials are verified.

Abstract: A system for predicting an anomalous request comprises a processor associated with a server. The processor is configured to parse a user profile from a plurality of user profiles to generate a first set of data objects associated with the first user profile. The processor is configured to compare the first set of the data objects to approved data, audit data, disapproved data to generate a second set of data objects with a set of anomalous data indicators for the first user profile. The processor is further configured to process the second set of the data objects through an anomaly learning model to determine a predictive degree of approval associated with the user profile. The processor is further configured to determine to approve, flag or disapprove the user profile based on the predictive degree of approval. The processor is further configured to assign a profile indicator to the user profile.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for interconnecting devices. One of the methods includes authenticating, by a security platform, a user. The method includes generating, by the security platform, an authentication token for the user. The method includes receiving a selection of an IoT application by the user, the IoT application configured to control an IoT device. The method includes providing, by the security platform, the authentication token to the IoT application to authenticate the user with the selected application. The method also includes providing, by the selected application, control of the IoT device to the user.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, to provide digital identification. One of these methods includes comparing the location of a requester of a digital identification to the location of an owner of the digital identification. The method also includes providing information about the digital identification to the requester based at least in part on determining that the requester and the owner are within a predetermined distance.

Abstract: Methods and system are described for changing a driveline gear range from a higher gear range to a lower gear range. The driveline may include two electric machines and four clutches in a four wheel drive configuration. The methods and systems permit a driveline to change from a higher gear range to a lower gear range without stopping a vehicle.

Abstract: Methods and system are described for changing a driveline gear range from a lower gear range to a higher gear range. The driveline may include two electric machines and four clutches in a four wheel drive configuration. The methods and systems permit a driveline to change from a lower gear range to a higher gear range in a way that may reduce torque disturbances that may result from gear lash.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, to provide digital identification. One of these methods includes receiving a request for a digital document from a digital wallet executing on a mobile device. The method includes identifying a digital document provider capable of providing the requested document. The method includes sending the request for the digital document to the identified digital document provider. The method includes receiving, from the digital document provider, information that enables the mobile device to view the digital document and does not enable the computer system to view the digital document.

Abstract: A vehicle includes a primary axle powered by an actuator and a secondary axle powered by a motor. The secondary axle includes a differential, first and second halfshafts, first and second wheels, a first electric clutch selectively coupling the first wheel to the first halfshaft, and a second electric clutch selectively coupling the second wheel to the second halfshaft. A vehicle controller is programmed to: responsive to a request to activate the secondary axle and a first speed difference between the first and second wheels being less than a first threshold, engage the first and second clutches at a same time, and, in response to the request to activate the secondary axle and the first speed difference between the first and second wheels exceeding the first threshold, engage one of the clutches and then subsequently engage the other of the clutches once the one of the clutches is fully engaged.

Abstract: A release mechanism for separating sections of mooring lines has a main body with two separable first and second halves or sections. A hydraulic assembly within the main body is controlled by an acoustic system, and moves a rod and button so as to move locking shoes within the main body. The locking shoes hold the first and second sections locked together, or alternatively release them to disconnect the mooring line. In addition to the acoustically controlled hydraulic assembly, the release mechanism has a mechanical disconnect, which is operated by pulling the release mechanism into a chain fairlead or the like, or by pulling an encircling member such as a trigger sleeve into the release mechanism. The release mechanism may include instrumentation to transmit various operating conditions of the release mechanism when in use.

Abstract: Methods and systems for receiving a detection of a physical presence of a user and, in response, initiating a start-up process on an enterprise device according to a profile associated with the user are described. Thereafter, the system receives authentication credentials at the enterprise device and the user is granted access to the enterprise device after the authentication credentials are verified.

Abstract: Methods and system are described for changing a driveline gear range from a lower gear range to a higher gear range. The driveline may include two electric machines and four clutches in a four wheel drive configuration. The methods and systems permit a driveline to change from a lower gear range to a higher gear range in a way that may reduce torque disturbances that may result from gear lash.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for interconnecting devices. One of the methods includes authenticating, by a security platform, a user. The method includes generating, by the security platform, an authentication token for the user. The method includes receiving a selection of an IoT application by the user, the IoT application configured to control an IoT device. The method includes providing, by the security platform, the authentication token to the IoT application to authenticate the user with the selected application. The method also includes providing, by the selected application, control of the IoT device to the user.

Abstract: A vehicle system and method for remote start operation in the vehicle system are provided. The method includes responsive to receiving a remote start request and while the vehicle is stationary, automatically engaging a wheel-arresting device coupled to a wheel in the vehicle. The method also includes when an electronically actuated clutch is automatically disengaged and subsequent to the automatic engagement of the wheel-arresting device, implementing remote start operation in an engine, where the wheel-arresting device is distinct from a secondary vehicle brake.

Abstract: A vehicle includes an powerplant, a manual transmission, and a clutch. A vehicle controller is programmed to automatically control operation of the clutch allowing the driver to shift gears by just operating the gear shifter. The vehicle also includes an input allowing the driver to override the controller and operate the clutch. The input is located on the gear shifter and is in electric communication with the controller. The controller is programmed to, inter alia, command the clutch to reduce clutch capacity responsive to receiving a signal from the sensor indicating grasping of the shifter.

Abstract: Methods and system are described for changing a driveline gear range from a higher gear range to a lower gear range. The driveline may include two electric machines and four clutches in a four wheel drive configuration. The methods and systems permit a driveline to change from a higher gear range to a lower gear range without stopping a vehicle.