Abstract: The present invention provides a retroviral or lentiviral vector having a viral envelope which comprises a mitogenic T-cell activating transmembrane protein which comprises: (i) a mitogenic domain which binds a mitogenic tetraspanin, and (ii) a transmembrane domain; wherein the mitogenic T-cell activating transmembrane protein is not part of a viral envelope glycoprotein. When cells such as T-cells or Natural Killer cells are transduced by such a viral vector, they are activated by the mitogenic T-cell activating transmembrane protein.

Abstract: The present invention provides a retroviral or lentiviral vector having a viral envelope which comprises a mitogenic T-cell activating transmembrane protein which comprises: (i) a mitogenic domain which binds a mitogenic tetraspanin, and (ii) a transmembrane domain; wherein the mitogenic T-cell activating transmembrane protein is not part of a viral envelope glycoprotein. When cells such as T-cells or Natural Killer cells are transduced by such a viral vector, they are activated by the mitogenic T-cell activating transmembrane protein.

Abstract: An illustrative apparatus includes a first substrate and a second substrate, wherein the first substrate includes a first plurality of adhering regions and a first plurality of print faces defined between perforated folds and the second substrate includes a second plurality of adhering regions and a second plurality of print faces defined between cut folds, and wherein the perforated folds and the cut folds are collinear. The second substrate may releasably adhere to the first substrate via the second plurality of adhering regions and the first plurality of adhering regions, respectively. Each of the second plurality of adhering regions may be individually released from each of the first plurality of adhering regions and separated along the cut folds to yield a first set of labels and each of the first plurality of adhering regions may be individually separated along the perforated folds to yield a second set of labels.

Abstract: A locating and identifying device for locating a vehicle includes a pole, a panel, and a coupling means. The panel is coupled to and extends from the pole proximate to a first end of the pole. The coupling means is coupled to a second end of the pole. The coupling means is configured to couple the pole to a vehicle, such as to the roof or to a roof rack, so that the pole extends upwardly from the vehicle to position the panel so that it is viewable to a user, enabling the user to locate and identify the vehicle.

Abstract: An illustrative apparatus includes a first substrate and a second substrate, wherein the first substrate includes a first plurality of adhering regions and a first plurality of print faces defined between perforated folds and the second substrate includes a second plurality of adhering regions and a second plurality of print faces defined between cut folds, and wherein the perforated folds and the cut folds are collinear. The second substrate may releasably adhere to the first substrate via the second plurality of adhering regions and the first plurality of adhering regions, respectively. Each of the second plurality of adhering regions may be individually released from each of the first plurality of adhering regions and separated along the cut folds to yield a first set of labels and each of the first plurality of adhering regions may be individually separated along the perforated folds to yield a second set of labels.

Abstract: A locating and identifying device for locating a vehicle includes a pole, a panel, and a coupling means. The panel is coupled to and extends from the pole proximate to a first end of the pole. The coupling means is coupled to a second end of the pole. The coupling means is configured to couple the pole to a vehicle, such as to the roof or to a roof rack, so that the pole extends upwardly from the vehicle to position the panel so that it is viewable to a user, enabling the user to locate and identify the vehicle.

Abstract: The present invention provides a retroviral or lentiviral vector having a viral envelope which comprises a mitogenic T-cell activating transmembrane protein which comprises: (i) a mitogenic domain which binds a mitogenic tetraspanin, and (ii) a transmembrane domain; wherein the mitogenic T-cell activating transmembrane protein is not part of a viral envelope glycoprotein. When cells such as T-cells or Natural Killer cells are transduced by such a viral vector, they are activated by the mitogenic T-cell activating transmembrane protein.

Abstract: A method includes applying a release formulation to a first substrate, wherein the release formulation is applied to a first portion of the first substrate leaving a second portion of the first substrate without the release formulation; applying the release formulation to a second substrate, wherein the release formulation is applied to a second portion of the second substrate leaving a first portion of the second substrate without the release formulation; applying an adhesive to the first substrate, wherein the adhesive covers at least a part of the first portion of the first substrate and at least a part of the second portion of the first substrate; and laminating the first substrate to the second substrate to form a laminated article; wherein the laminated article is configured to transfer the adhesive on the first portion of the first substrate to the first portion of the second substrate upon separation of the first substrate from the second substrate.

Abstract: The disclosure provides a method of culturing cells of the mesenchymal cell lineage, said method comprising contacting the cells with a culture media comprising a CSF1R kinase inhibitor. The disclosure also provides a method of culturing cells from bone marrow and/or compact bone to enrich the cells with cells of the mesenchymal cell lineage comprising contacting the cells with a culture media comprising a CSF1R kinase inhibitor. Cell culture media comprising a CSF1R kinase inhibitor and useful for culturing cells of the mesenchymal cell lineage and/or enriching cells of the mesenchymal cell lineage is also provided.

Abstract: An illustrative apparatus includes a first substrate and a second substrate. The first substrate includes a first adhesive-receiving face. The first adhesive-receiving face includes a first adhesive-coated region and a first release region. The first substrate also includes a first print receiving face opposite the first adhesive-receiving face. The second substrate includes a second adhesive-receiving face. The second adhesive-receiving face includes a second adhesive-coated region and a second release region. The second substrate also includes a second print receiving face opposite the second adhesive-receiving face. The first adhesive-coated region is releasably adhered the second release region and the second adhesive-coated region is releasably adhered to the first release region.

Abstract: An illustrative apparatus includes a first substrate and a second substrate. The first substrate includes a first adhesive-receiving face. The first adhesive-receiving face includes a first adhesive-coated region and a first release region. The first substrate also includes a first print receiving face opposite the first adhesive-receiving face. The second substrate includes a second adhesive-receiving face. The second adhesive-receiving face includes a second adhesive-coated region and a second release region. The second substrate also includes a second print receiving face opposite the second adhesive-receiving face. The first adhesive-coated region is releasably adhered the second release region and the second adhesive-coated region is releasably adhered to the first release region.

Abstract: An illustrative apparatus includes a first substrate and a second substrate. The first substrate includes a first adhesive-receiving face. The first adhesive-receiving face includes a first adhesive-coated region and a first release region. The first substrate also includes a first print receiving face opposite the first adhesive-receiving face. The second substrate includes a second adhesive-receiving face. The second adhesive-receiving face includes a second adhesive-coated region and a second release region. The second substrate also includes a second print receiving face opposite the second adhesive-receiving face. The first adhesive-coated region is releasably adhered the second release region and the second adhesive-coated region is releasably adhered to the first release region.

Abstract: The disclosure provides a method of culturing cells of the mesenchymal cell lineage, said method comprising contacting the cells with a culture media comprising a CSF1R kinase inhibitor. The disclosure also provides a method of culturing cells from bone marrow and/or compact bone to enrich the cells with cells of the mesenchymal cell lineage comprising contacting the cells with a culture media comprising a CSF1R kinase inhibitor. Cell culture media comprising a CSF1R kinase inhibitor and useful for culturing cells of the mesenchymal cell lineage and/or enriching cells of the mesenchymal cell lineage is also provided.

Abstract: A method of manufacturing gas and/or fuel swirlers for fuel injectors and combustor domes and cone-shaped swirlers so manufactured are disclosed. The disclosed conical swirlers feature cut-through slots on a cone-shaped body. The contour and spacing of the slots are configured and arranged to accommodate a wide range of requirements for fluid flow areas and swirl strengths. Preferably, the cone-shaped swirlers can be manufactured by wire EDM processing. More preferably, multiple cone-shaped swirlers can be manufactured simultaneously by nesting wirier blanks in a stack and wire EDM processing the stack as a unit. The cone-shaped pinwheel swirler fits well into various fuel injector heads, enabling the injectors to reduce the frontal surface area and flat area for minimal potential of carbon formation.

Abstract: A method of manufacturing gas and/or fuel swirlers for fuel injectors and combustor domes and cone-shaped swirlers so manufactured are disclosed. The disclosed conical swirlers feature cut-through slots on a cone-shaped body. The contour and spacing of the slots are configured and arranged to accommodate a wide range of requirements for fluid flow areas and swirl strengths. Preferably, the cone-shaped swirlers can be manufactured by wire EDM processing. More preferably, multiple cone-shaped swirlers can be manufactured simultaneously by nesting swirler blanks in a stack and wire EDM processing the stack as a unit. The cone-shaped pinwheel swirler fits well into various fuel injector heads, enabling the injectors to reduce the frontal surface area and flat area for minimal potential of carbon formation.

Abstract: A protective liner includes a base layer that can be affixed to an aircraft canopy or other substrate, a conductive polymeric interlayer positioned over the base layer, and a conductive top layer containing a reactive organic salt, or a hygroscopic salt, positioned over the conductive polymeric interlayer. The substrate can also be treated with a multilayer stack (including a substrate base coat layer, a metal layer positioned over the substrate base layer, a metal oxide layer positioned over the metal layer, and a tie layer positioned over the metal oxide layer). The protective liner can be affixed to a pretreated substrate by lamination or other means to form an enhanced, multilayer stack having beneficial properties.

Abstract: A fuel injection and mixing system is provided that is suitable for use with various types of fuel reformers. Preferably, the system includes a piezoelectric injector for delivering atomized fuel, a gas swirler, such as a steam swirler and/or an air swirler, a mixing chamber and a flow mixing device. The system utilizes ultrasonic vibrations to achieve fuel atomization. The fuel injection and mixing system can be used with a variety of fuel reformers and fuel cells, such as SOFC fuel cells.

Abstract: A fuel injection and mixing system is provided. The system includes an injector body having a fuel inlet and a fuel outlet, and defines a fuel flow path between the inlet and outlet. The fuel flow path may include a generally helical flow passage having an inlet end portion disposed proximate the fuel inlet of the injector body. The flow path also may include an expansion chamber downstream from and in fluid communication with the helical flow passage, as well as a fuel delivery device in fluid communication with the expansion chamber for delivering fuel. Heating means is also provided in thermal communication with the injector body. The heating means may be adapted and configured for maintaining the injector body at a predetermined temperature to heat fuel traversing the flow path. A method of preheating and delivering fuel is also provided.

Abstract: A protective liner includes a base layer that can be affixed to an aircraft canopy or other substrate, a conductive polymeric interlayer positioned over the base layer, and a conductive top layer containing a reactive organic salt, or a hygroscopic salt, positioned over the conductive polymeric interlayer. The substrate can also be treated with a multilayer stack (including a substrate base coat layer, a metal layer positioned over the substrate base layer, a metal oxide layer positioned over the metal layer, and a tie layer positioned over the metal oxide layer). The protective liner can be affixed to a pretreated substrate by lamination or other means to form an enhanced, multilayer stack having beneficial properties.

Abstract: Systems and methods for injecting and mixing a liquid hydrocarbon fuel to provide a uniform, homogenous fuel vapor mixture for introduction into a fuel reformer for use with a fuel cell are disclosed. Preferably, the system includes a fuel injector that generates and aspirate a liquid fuel in the presence of an atomizing gas stream; a diverging-converging mixing chamber, into which the atomized fuel and a secondary fluid stream are introduced, to enhance the mixing of the fuel and the added heated gas or steam; and a mixer/swirler, which can be centrally located in the mixing chamber between the upper and lower chambers, to stabilize the fuel vapor mixture further for greater uniformity and homogeneity. More preferably, grooves and/or brazed wires can be provided on the surfaces of the mixing chamber and/or mixer/swirler to channel any accumulated fuel so as to provide sufficient time to evaporate the accumulated fuel.