Abstract: The present disclosure provides food supplements comprising proteases that can digest a variety of food proteins to enhance their protein bioavailability in the gut.

Abstract: The present invention relates to compositions and methods for malodor reduction. The malodor control compositions are suitable for use in a variety of applications, including use in consumer products, for example, air freshening compositions, laundry detergents, fabric enhancers, surface cleaners, beauty care products, dish care products, diapers, feminine protection articles, animal and pet litter compositions and plastic films for garbage bags. Such malodor control technologies do not unduly interfere with the scent of the perfumed or unperfumed situs that is treated with the malodor control technology.

Abstract: Provided are compositions and methods for generating two-dimensional (2D) intestinal epithelial cell cultures for all segments of mouse and human small and large intestines. The compositions and methods described herein utilize primary human or murine intestinal cells and do not rely on cancer cell lines, resulting in 2D cultures that are representative of homeostatic epithelial gene expression and function. Also provided are compositions and methods of utilizing the cultures described herein in a high-throughput system for compound evaluation.

Abstract: An inventive animal collar device is described herein that monitors location, physiological information and/or environmental information relating to an animal wearing the device. The collar may include multiple sensors and other electrical components embedded within the collar body that provide means for: tracking and monitoring an animal's activity and whereabouts, increasing visibility of the collar, and storing and retrieving animal, environment and system information. The collar may implement one or more wired or wireless communication devices so that the collar may transmit data to a connected computing device. The collar may also include one or more antennas to send and/or receive location information associated with the device. The collar may include a removable module that attaches to the collar via a module dock. The removable module may include any of the electronic components and may allow for the collar body to remain on the animal during information transfer and/or charging.

Abstract: Oral administration of ALV003 can protect celiac disease patients and patients otherwise suffering from gluten-intolerance from the harmful effects of ingesting food containing gluten.

Abstract: An inventive animal collar device is described herein that monitors location, physiological information and/or environmental information relating to an animal wearing the device. The collar may include multiple sensors and other electrical components embedded within the collar body that provide means for: tracking and monitoring an animal's activity and whereabouts, increasing visibility of the collar, and storing and retrieving animal, environment and system information. The collar may implement one or more wired or wireless communication devices so that the collar may transmit data to a connected computing device. The collar may also include one or more antennas to send and/or receive location information associated with the device. The collar may include a removable module that attaches to the collar via a module dock. The removable module may include any of the electronic components and may allow for the collar body to remain on the animal during information transfer and/or charging.

Abstract: Oral administration of ALV003 can protect celiac disease patients and patients otherwise suffering from gluten-intolerance from the harmful effects of ingesting food containing gluten.

Abstract: Gluten-degrading proteases can be used to degrade gluten and for making gluten-containing food safer for patients suffering from gluten intolerance. The present invention provides recombinant expression vectors encoding the proteases of the invention and methods for using such vectors to produce the encoded proteases. In another aspect, the present invention provides pharmaceutical formulations and unit dose forms suitable for oral administration.

Abstract: Pharmaceutical formulations of orally administered proteins can be stabilized from oxidative degradation and inactivation in the stomach and GI tract by the addition of an antioxidant.

Abstract: Transglutaminase inhibitors and methods of use thereof are provided.

Abstract: Gluten-degrading proteases can be used to degrade gluten and for making gluten-containing food safer for patients suffering from gluten intolerance.

Abstract: A combination enzyme product consisting of a glutamine specific endoprotease and a prolyl endopeptidase is provided. Both enzymes are active and stable in the stomach and can therefore be administered as lyophilized powders or simple capsules/tablets. A ratio of the two enzymes is used to maximize their synergy.

Abstract: In one embodiment, the present disclosure is a method and apparatus for provisioning a backup signaling channel. In one embodiment, a method for provisioning a backup D channel in a media gateway includes provisioning a primary D channel on a first media gateway card in the media gateway and provisioning the backup D channel on a second media gateway card in the media gateway that is different from the first media gateway card, wherein the backup D channel backs up the primary D channel.

Abstract: Transglutaminase inhibitors and methods of use thereof are provided.

Abstract: Pharmaceutical formulations of orally administered proteins can be stabilized from oxidative degradation and inactivation in the stomach and GI tract by the addition of an antioxidant.

Abstract: In one embodiment, the present disclosure is a method and apparatus for provisioning a backup signaling channel. In one embodiment, a method for provisioning a backup D channel in a media gateway includes provisioning a primary D channel on a first media gateway card in the media gateway and provisioning the backup D channel on a second media gateway card in the media gateway that is different from the first media gateway card, wherein the backup D channel backs up the primary D channel.

Abstract: A combination enzyme product consisting of a glutamine specific endoprotease and a prolyl endopeptidase is provided. Both enzymes are active and stable in the stomach and can therefore be administered as lyophilized powders or simple capsules/tablets. A ratio of the two enzymes is used to maximize their synergy.

Abstract: Transglutaminase inhibitors and methods of use thereof are provided.

Abstract: Transglutaminase inhibitors and methods of use thereof are provided.

Abstract: Detection of toxic gluten oligopeptides refractory to digestion and antibodies and T cells responsive thereto can be used to diagnose Celiac Sprue. Analogs of such oligopeptides are useful in the inhibition of immune responses.