Patents by Inventor John Simmons

John Simmons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210363696
    Abstract: The present invention provides for a method to deconstruct a biomass comprising: (a) introducing one or more individual components of an ionic liquid (IL) or deep eutectic solvent (DES) to a biomass, wherein the one or more individual components, and optionally any components already present in the biomass, form an IL or DES, or mixture thereof, which solubilizes the biomass to form a solubilized biomass mixture, wherein at least one individual component is introduced to the biomass separately from any other individual component; (b) optionally introducing an enzyme and/or a microbe to the solubilized biomass mixture such that the enzyme and/or microbe produces a sugar from the solubilized biomass mixture; and, (c) optionally separating the sugar from the solubilized biomass mixture.
    Type: Application
    Filed: June 4, 2021
    Publication date: November 25, 2021
    Inventors: Harsha D. Magurudeniya, Ezinne Achinivu, Blake A. Simmons, John M. Gladden
  • Publication number: 20210332530
    Abstract: The present invention provides for a method to deconstruct a biomass: the method comprising: (a) ensiling a biomass to produce comprising one or more organic acids, and (b) introducing a solvent to the ensiled biomass to dissolve at least part of solid biomass in the solvent, wherein the solvent is an ionic liquid (IL) or deep eutectic solvent (DES), or mixture thereof, to form a solubilized biomass mixture.
    Type: Application
    Filed: April 27, 2021
    Publication date: October 28, 2021
    Inventors: Harsha D. Magurudeniya, Alberto Rodriguez, Nawa Raj Baral, Blake A. Simmons, John M. Gladden
  • Publication number: 20210317481
    Abstract: The present invention also provides for a method to deconstruct a biomass: the method comprising: (a) introducing a solvent to a biomass to dissolve at least part of solid biomass in the solvent, wherein the solvent comprises (i) a metal salt, and (ii) an ionic liquid (IL) or deep eutectic solvent (DES), or mixture thereof, to form a solubilized biomass mixture; (b) optionally introducing an enzyme and/or a microbe to the composition such that the enzyme and/or microbe produce a biofuel and/or chemical compound from the solubilized biomass; and, (c) optionally the biofuel and/or chemical compound is separated from the composition.
    Type: Application
    Filed: April 1, 2021
    Publication date: October 14, 2021
    Inventors: Lalitendu Das, Hemant Choudhary, John M. Gladden, Blake A. Simmons
  • Publication number: 20210290416
    Abstract: Medical appliances may be formed of multilayered constructs. The layers of the constructs may be configured with various physical properties or characteristics. The disposition and arrangement of each layer may be configured to create an overall construct with a combination of the individual properties of the layers. Constructs may be used to create vascular prostheses or other medical devices.
    Type: Application
    Filed: June 7, 2021
    Publication date: September 23, 2021
    Inventors: John Hall, Wayne Mower, Rachel Simmons, Bart Dolmatch
  • Publication number: 20210291832
    Abstract: A system for assisting in aligning a vehicle for hitching with a trailer includes a vehicle steering system, a wireless communication module, a detection system outputting a signal including scene data of an area to a rear of the vehicle, and a controller. The controller receives, via the wireless communication module, an automated hitching initiation command from an external wireless device, receives the scene data and identifying the trailer within the area to the rear of the vehicle, derives a backing path to align a hitch ball mounted on the vehicle to a coupler of the trailer, and controls the vehicle steering system to maneuver the vehicle including reversing along the backing path.
    Type: Application
    Filed: March 17, 2020
    Publication date: September 23, 2021
    Applicant: Ford Global Technologies, LLC
    Inventors: Kyle Simmons, Luke Niewiadomski, Roger Trombley, Frederic Christen, Christoph Kessler, Katherine Rouen, Erick Michael Lavoie, Hamid M. Golgiri, Bruno Sielly Jales Costa, Nikhil Nagraj Rao, Vidya Nariyambut Murali, John Michael Celli, Frank Golub, Seyed Armin Raeis Hosseiny, Bo Bao, Siyuan Ma, Hemanth Yadav Aradhyula
  • Publication number: 20210275952
    Abstract: A filter and kit assembly for securing to one or more intake surfaces associated with a V-shaped heat exchanger unit. A screen includes a reinforced edge, within which is configured a plurality of spaced apart grommets aligning with and receiving therethrough engaging portions of the fasteners. In one variant, a frame is constructed for supporting the fasteners and attached filter and which is subsequently secured by clips against a flange surface surrounding the intake opening. In a further variant, the screen is configured in wrap-around fashion for supporting against first and second consecutively arranged intake openings along with an interconnecting intermediate flange surface.
    Type: Application
    Filed: March 2, 2021
    Publication date: September 9, 2021
    Inventors: Randy Simmons, John Gordon Grenville, Steven George Bell
  • Publication number: 20210269810
    Abstract: The present invention provides for a genetically modified fungal host cell capable of producing prespatane and/or epi-isozizaene comprising prespatane synthase (PPS) and/or epi-isozizaene synthase (EIZS).
    Type: Application
    Filed: February 26, 2021
    Publication date: September 2, 2021
    Inventors: Gina Marie Geiselman, James Kirby, Taek Soon Lee, John M. Gladden, Blake A. Simmons
  • Publication number: 20210259982
    Abstract: The present disclosure generally relates to nanoparticles comprising an endo-lysosomal escape agent, a nucleic acid, and a polymer. Other aspects include methods of making and using such nanoparticles.
    Type: Application
    Filed: February 18, 2021
    Publication date: August 26, 2021
    Applicant: Pfizer Inc.
    Inventors: Allen Thomas Horhota, Young-Ho Song, Ujjwal Chaitanya Joshi, Nicholas Jon Boylan, Matthew John Simmons
  • Publication number: 20210261516
    Abstract: Methods for treating a tumor, such as a benign or malignant tumor, are disclosed herein. The methods include administering a therapeutically effective amount of a small molecule that selectively binds to and stabilizes G-quadruplex DNA in the promoter of the c-MYC gene to the subject. The methods are also of use to decrease the size and/or number of metastases. Compounds for use in the disclosed methods are also provided.
    Type: Application
    Filed: May 3, 2021
    Publication date: August 26, 2021
    Applicants: The United States of America, as represented by the Secretary, Department of Health and Human Servic, Yale University
    Inventors: John Schneekloth, JR., John Simmons, Kenneth Felsenstein, Beverly Mock, Lindsey Saunders, Peter Gareiss, David Calabrese, Elena Leon
  • Publication number: 20210258756
    Abstract: A location-based risk alerting system is disclosed. When information regarding a risk assessment situation is received, the location and time attributes of the risk assessment situation are extracted, a risk score is calculated and a risk alert is generated to include the attributes and the risk score upon validating the received information for risk. The risk alert is transmitted to client devices of subscribers where a user-specific risk score is calculated at each client device based on a comparison of the distance of the client device from the location attribute and the time at which the risk alert is received with the time attribute. The risk alert is displayed at the client device based on the user-specific risk score and information regarding the user is shared with trusted authorities upon receiving user consent.
    Type: Application
    Filed: January 12, 2021
    Publication date: August 19, 2021
    Applicant: ACCENTURE GLOBAL SOLUTIONS LIMITED
    Inventors: Anthony Peter Mcdougall, Michael John Simmons
  • Publication number: 20210233724
    Abstract: High temperature switch apparatus are disclosed. An example apparatus includes a ceramic contact base having an opening therein configured to removably receive a contact, a first ceramic plunger housing portion and a second ceramic plunger housing portion, the first ceramic plunger housing portion including a first protrusion, the second ceramic plunger housing portion including a first recess, the first recess to receive the first protrusion, and a first ceramic contact housing portion and a second ceramic contact housing portion, the first ceramic contact housing portion including a second protrusion and a first cavity, the second ceramic contact housing portion including a second recess and a second cavity, the first ceramic plunger housing portion, the second ceramic plunger housing portion, and the ceramic contact base configured to be coupled in between the first and second cavities when the second recess receives the second protrusion.
    Type: Application
    Filed: February 20, 2020
    Publication date: July 29, 2021
    Inventors: Robert L. LaFountain, Anthony Wayne Klosterman, Michael John Simmons
  • Publication number: 20210184245
    Abstract: Described herein is an aqueous aluminum ion battery featuring an aluminum or aluminum alloy/composite anode, an aqueous electrolyte, and a manganese oxide, aluminosilicate or polymer-based cathode. The battery operates via an electrochemical reaction that entails an actual transport of aluminum ions between the anode and cathode. The compositions and structures described herein allow the aqueous aluminum ion battery described herein to achieve: (1) improved charge storage capacity; (2) improved gravimetric and/or volumetric energy density; (3) increased rate capability and power density (ability to charge and discharge in shorter times); (4) increased cycle life; (5) increased mechanical strength of the electrode; (6) improved electrochemical stability of the electrodes; (7) increased electrical conductivity of the electrodes, and (8) improved ion diffusion kinetics in the electrodes as well as the electrolyte.
    Type: Application
    Filed: February 24, 2021
    Publication date: June 17, 2021
    Inventors: Rahul Mukherjee, Kripa Kiran Varanasi, Trevor John Simmons, Mukesh Chatter, Nikhil Ashok Koratkar
  • Publication number: 20210176242
    Abstract: An adaptive user authentication system is disclosed that executes user authentication by verifying user identity using different authentication steps based on a risk score. The risk score enables determining if the requesting user's identity is to be verified. If it is determined that the user identity is to be verified, a sequence of authentication steps is implemented wherein more and more data is collected regarding the user as the user fails to be authenticated at each of the authentication steps. A first authentication step includes a numerical-based authentication step followed by a second authentication step including a live image authentication. If the user fails to be authenticated at either the first or the second authentication steps then a third authentication step to verify the user's passport is implemented.
    Type: Application
    Filed: November 25, 2020
    Publication date: June 10, 2021
    Applicant: ACCENTURE GLOBAL SOLUTIONS LIMITED
    Inventors: Anthony Peter MCDOUGALL, Michael John SIMMONS, Gerard Johan LANDMAN
  • Patent number: 11014902
    Abstract: Methods for treating a tumor, such as a benign or malignant tumor, are disclosed herein. The methods include administering a therapeutically effective amount of a small molecule that selectively binds to and stabilizes G-quadruplex DNA in the promoter of the c-MYC gene to the subject. The methods are also of use to decrease the size and/or number of metastases. Compounds for use in the disclosed methods are also provided.
    Type: Grant
    Filed: March 30, 2020
    Date of Patent: May 25, 2021
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: John Schneekloth, Jr., John Simmons, Kenneth Felsenstein, Beverly Mock, Lindsey Saunders, David Calabrese, Elena Leon
  • Patent number: 10978734
    Abstract: Described herein is an aqueous aluminum ion battery featuring an aluminum or aluminum alloy/composite anode, an aqueous electrolyte, and a manganese oxide, aluminosilicate or polymer-based cathode. The battery operates via an electrochemical reaction that entails an actual transport of aluminum ions between the anode and cathode. The compositions and structures described herein allow the aqueous aluminum ion battery described herein to achieve: (1) improved charge storage capacity; (2) improved gravimetric and/or volumetric energy density; (3) increased rate capability and power density (ability to charge and discharge in shorter times); (4) increased cycle life; (5) increased mechanical strength of the electrode; (6) improved electrochemical stability of the electrodes; (7) increased electrical conductivity of the electrodes, and (8) improved ion diffusion kinetics in the electrodes as well as the electrolyte.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: April 13, 2021
    Assignee: Everon24, Inc.
    Inventors: Rahul Mukherjee, Kripa Kiran Varanasi, Trevor John Simmons, Mukesh Chatter, Nikhil Ashok Koratkar
  • Patent number: 10952972
    Abstract: The present disclosure generally relates to nanoparticles comprising an endo-lysosomal escape agent, a nucleic acid, and a polymer. Other aspects include methods of making and using such nanoparticles.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: March 23, 2021
    Assignee: Pfizer Inc.
    Inventors: Allen Thomas Horhota, Young-Ho Song, Ujjwal Chaitanya Joshi, Nicholas Jon Boylan, Matthew John Simmons
  • Publication number: 20210059953
    Abstract: Provided herein are lipid nanoparticle formulations that comprise an ionizable lipid and non-viral, capsid-free DNA vectors with covalently-closed ends.
    Type: Application
    Filed: September 7, 2018
    Publication date: March 4, 2021
    Inventors: Robert Michael Kotin, Ozan Alkan, Douglas Anthony Kerr, Ara Karl Malakian, Matthew John Simmons, Matthew G. Stanton, Jie Su, Teresa L. Wright
  • Publication number: 20210057171
    Abstract: Electrical switch contact sets are disclosed. A disclosed example apparatus includes a movable platform having first and second contacts, where the first and second contacts electrically coupled via the movable platform, and a stationary portion having third and fourth contacts, where the movable platform is movable to bring the first and second contacts in contact with the third and fourth contacts, respectively, to simultaneously close a current path of an electrical circuit associated with the first, second, third and fourth contacts.
    Type: Application
    Filed: August 22, 2019
    Publication date: February 25, 2021
    Inventors: Robert L. LaFountain, Michael John Simmons
  • Publication number: 20200339801
    Abstract: Compositions of resin and a mesh or mesh-like material wherein the material is less than 10% by weight of the finished composition. In some embodiments, the mesh or mesh-like material in the compositions are non-homogenous and discontinuous. Some embodiments include not more than 3% by weight of tissue paper as the mesh or mesh-like material, while others utilize an order of magnitude less.
    Type: Application
    Filed: April 24, 2019
    Publication date: October 29, 2020
    Inventors: Jean Alvarado, John Simmons, Kay Rehberg
  • Publication number: 20200308128
    Abstract: Methods for treating a tumor, such as a benign or malignant tumor, are disclosed herein. The methods include administering a therapeutically effective amount of a small molecule that selectively binds to and stabilizes G-quadruplex DNA in the promoter of the c-MYC gene to the subject. The methods are also of use to decrease the size and/or number of metastases. Compounds for use in the disclosed methods are also provided.
    Type: Application
    Filed: March 30, 2020
    Publication date: October 1, 2020
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Servic
    Inventors: John Schneekloth, JR., John Simmons, Kenneth Felsenstein, Beverly Mock, Lindsey Saunders, David Calabrese, Elena Leon