Abstract: The present application relates to affecting weight loss comprising administering a therapeutically effective amount of (1r,1?R,4R)-4-methoxy-5?-methyl-6?-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3?H-dispiro[cyclohexane-1,2?-indene-1?,2?-imidazol]-4?-amine, or a pharmaceutically acceptable salt thereof (e.g., the camsylate salt of (1r,1?R,4R)-4-methoxy-5?-methyl-6?-[5-(prop-1-yn-1-yl)pyridin-3-yl]-3?H-dispiro[cyclohexane-1,2?-indene-1?,2?-imidazol]-4?-amine).

Abstract: A child motion apparatus includes a base, a seat arranged above the base, and an upright column disposed below the seat. The seat includes a bottom frame segment and a seatback frame segment, the bottom frame segment having a front and a rear end, the seatback frame segment being pivotally connected with the rear end of the bottom frame segment. The upright column pivotally supports the seat above the base, and is connected with the bottom frame segment at a location between the front end and the rear end thereof.

Abstract: A child motion apparatus includes a base, a seat arranged above the base, and an upright column disposed below the seat. The seat includes a bottom frame segment and a seatback frame segment, the bottom frame segment having a front and a rear end, the seatback frame segment being pivotally connected with the rear end of the bottom frame segment. The upright column pivotally supports the seat above the base, and is connected with the bottom frame segment at a location between the front end and the rear end thereof.

Abstract: An article temperature control system includes an article having flexible tubing through it for circulating a heat transfer fluid and an article coupling affixed to distal ends of the flexible tubing. The article coupling releasably couples to a heat exchanger having a thermoelectric cooling/heating unit having one or more TEC plates, an aluminum heat sink, a fan and a controller in electrical communication with the TEC plates, a heat exchanger coupling adapted to releasably connect to the article coupling, an outlet line fluidly connecting the thermoelectric cooling/heating unit and the heat exchanger coupling, a return line fluidly connecting the thermoelectric cooling/heating unit and the heat exchanger coupling, a fluid block in fluid communication with the outlet and return lines, the fluid block forming a housing for the TEC plates, a pump in fluid communication with at least one of the outlet and return lines, and a power supply in electrical communication with the controller and the pump.

Abstract: A personal temperature control system includes an article having flexible tubing through it for circulating a heat transfer fluid and an article coupling affixed to distal ends of the flexible tubing. The article coupling releasably couples to a heat exchanger having a thermoelectric cooling/heating unit having one or more TEC plates, an aluminum heat sink, a fan and a controller in electrical communication with the TEC plates, a heat exchanger coupling adapted to releasably connect to the article coupling, an outlet line fluidly connecting the thermoelectric cooling/heating unit and the heat exchanger coupling, a return line fluidly connecting the thermoelectric cooling/heating unit and the heat exchanger coupling, a fluid reservoir in fluid communication with the outlet and return lines, the fluid reservoir forming a housing for the TEC plates, a pump in fluid communication with at least one of the outlet and return lines, and a power supply in electrical communication with the controller and the pump.

Abstract: The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, the use of such polypeptides and fragmented peptides in cellular and immune reactions and as molecular weight markers, the use of such polypeptides and fragmented peptides as controls for peptide fragmentation, and kits comprising these reagents.

Abstract: A variable compression engine has a relief valve disposed in the combustion chamber thereof to reduce compression. The relief valve is open for a portion of the compression stroke of the engine. The open relief valve permits a portion of the fuel/air mixture introduced via the intake valve to leave the combustion chamber and return to the fuel supply or intake manifold via a check valve that prevent flow into the combustion chamber through the relief valve. Timing of the opening and closing of the relief valve is selectable via a cam-operated hydraulically operated by a camshaft rotating once for every two revolutions of the engine's crankshaft, or timing of opening and closing may be achieved by other suitable mechanisms. Additionally, the height of lift of the relief valve can be varied to further adjust compression around a selected relief valve opening point.

Abstract: A vehicle seat and a power seat adjuster assembly for a vehicle seat. The power seat adjuster assembly includes a track assembly having a lead screw and a lead screw constraint.

Abstract: A method for loading software items on a mobile platform computer based system includes storing published content in a published content repository of a distributed data manager system (DDMS) included in the DDLMS. At least one assigned software part generated using the published content from the published content repository is stored in a DDMS fleet content repository. The assigned software part is communicated to the staging area repository of OCS platform over a secure link. The staged software part is transferred to an installed software parts repository of the OCS after the entire software part is staged in the staging area repository.

Abstract: The invention is directed to novel, purified and isolated IL-1 zeta and Xrec2 polypeptides and fragments thereof, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and uses thereof.

Abstract: A novel polypeptide that functions as an IL-18 receptor is disclosed. The receptor is multimeric and includes at least one AcPL polypeptide, or fragment thereof, and at least one IL-1Rrp1 polypeptide, or fraction thereof. The receptor binds IL-18 and finds use in inhibiting biological activities mediated by IL-18.

Abstract: A method for loading software items on a mobile platform computer based system includes storing published content in a published content repository of a distributed data manager system (DDMS) included in the DDLMS. At least one assigned software part generated using the published content from the published content repository is stored in a DDMS fleet content repository. The assigned software part is communicated to the staging area repository of OCS platform over a secure link. The staged software part is transferred to an installed software parts repository of the OCS after the entire software part is staged in the staging area repository.

Abstract: DNA encoding SIGIRR polypeptides and methods for using the encoded polypeptides are disclosed.

Abstract: The invention is directed to purified and isolated novel TSLP polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, and the uses of the above.

Abstract: DNA encoding IL-1R AcP splice variant polypeptides, the polypeptides and methods for using the encoded polypeptides are disclosed.

Abstract: A new line attachment which is easily removed and attached to a fishing line. The attachment body features a longitudinal bore and slot through which a bushing and fishing line can be inserted. The bushing also features a longitudinal bore and slot through which a fishing line can be fed. The longitudinal bore and slot in the bushing also enable the bushing to be compressed to fit securely into the body of the attachment body, thereby preventing the attachment body and bushing assembly from becoming unintentionally separated from the fishing line. The preferred embodiment of the invention further comprises a rib on the outside surface of the bushing that prevents rotational movement of the bushing vis-à-vis the attachment body.

Abstract: An automotive slouch rear seat with improved adjustability is provided including an upper seat back and a lower seat bottom. The upper seat back includes a fixed rear seat back, a pivotal seat back, and a sliding seat back. The pivotal seat back has an upper end and a lower end for connecting to the lower seat bottom. The sliding seat back is slidably engaged to the fixed rear seat back. The sliding seat back is rotatably engaged to the upper end of the pivotal seat back. The lower seat bottom includes a fixed rear seat bottom, and a sliding seat lower. The sliding seat lower is slidably engaged to the fixed rear seat bottom. The sliding seat lower is rotatably engaged to the lower end of the pivotal seat back. Also, an automotive slouch rear seat assembly and a method of assembling a pre-installation automotive slouch rear seat assembly are provided.

Abstract: The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, the use of such polypeptides in cellular and immune reactions, the use of such polypeptides in screening for agonists or antagonists of IL-1 epsilon activity, and kits comprising such polypeptides.

Abstract: The invention is directed to purified and isolated novel human IL-1 epsilon polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides derived from these polypeptides, the use of such polypeptides and fragmented peptides in cellular and immune reactions and as molecular weight markers, the use of such polypeptides and fragmented peptides as controls for peptide fragmentation, and kits comprising these reagents.

Abstract: DNA encoding IL-1 delta polypeptides and methods for using the encoded polypeptides are disclosed.