Patents by Inventor John Skonier

John Skonier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ligands for TGF-beta binding proteins and uses thereof
    Patent number: 7226902
    Abstract: Compositions and methods are provided that relate to the unexpected specific association of (i) the TGF-beta binding protein sclerostin with the BMP antagonist protein chordin to form a complex, and of (ii) the TGF-beta binding protein sclerostin with the BMP antagonist protein noggin to form a complex, either of which complex is incapable of binding to a TGF-beta superfamily member such as a BMP. The invention provides isolated complexes for use in screening assays to identify agents that modulate bone mineralization, and offers other related advantages.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: June 5, 2007
    Assignee: Celltech R&D, Inc.
    Inventors: David G. Winkler, John Latham, John Skonier, Diana Shpektor, Trenton Hayes, James Geoghegan
  • Ligands for TGF-beta binding proteins and uses thereof
    Publication number: 20050085418
    Abstract: Compositions and methods are provided that relate to the unexpected specific association of (i) the TGF-beta binding protein sclerostin with the BMP antagonist protein chordin to form a complex, and of (ii) the TGF-beta binding protein sclerostin with the BMP antagonist protein noggin to form a complex, either of which complex is incapable of binding to a TGF-beta superfamily member such as a BMP. The invention provides isolated complexes for use in screening assays to identify agents that modulate bone mineralization, and offers other related advantages.
    Type: Application
    Filed: March 12, 2004
    Publication date: April 21, 2005
    Applicant: CELLTECH R & D LTD.
    Inventors: David Winkler, John Latham, John Skonier, Diana Shpektor, Trenton Hayes, James Geoghegan