Abstract: A cocrystal having the formula LiX·aM, or a solvate or hydrate thereof, wherein X is a conjugate base of an organic acid, M is a neutral organic molecule, and a is from 0.5 to 4, pharmaceutical compositions comprising such cocrystals, cocrystal solvates, or cocrystal hydrates, and methods of preparing such cocrystals, cocrystal solvates, or cocrystal hydrates, and such pharmaceutical compositions.

Abstract: The present invention pertains to the field of Digital and Virtual Reality, addressing the deficiency in current technology for creating authentic digital replicas that faithfully capture user behaviors, emotions, metaphysical essence, and physical attributes of objects and environments. Existing technologies fall short in providing a comprehensive solution. This invention fills the void by offering a platform to generate precise digital replicas derived from data collected through wearable and external sensors. Users can then license or rent these replicas for diverse applications, such as connecting with deceased loved ones or evaluating products and experiences. Moreover, the invention facilitates the fusion of user essence with the physical characteristics of places and objects, enabling the creation of anthropomorphized and anomalous entities.

Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.

Abstract: A system and method for determining location information of a portable device relative to an object is provided. In one embodiment, a booking control system is provided for booking a resource or service associated with the object. The system and method may determine location information with respect to the portable device, and identify the user as checked-in or checked-out (e.g., the resource is in-use or out of use) based on the location information.

Abstract: System, process and device configurations are provided for game guides. A method can include detecting user interface selection of a game guide, updating display output and presentation of game guide content. A user interface, processes and device configurations are provided to provide game guidance to assist players of a game find detailed context sensitive game guidance. Game guidance can reduce frustration, increase engagement and keep players in a game. Game guides can present game guide assistance videos that may be presented in addition to game content, such as side-by-side or picture-in-picture to present content to assist a player accomplish tasks of a game and to locate trophies. Game guide elements are provided that include features, such as searching and selection of game guide assistance. Game guide elements can include features for selection of sources and to launch game content. Processes and configurations are also provided for determining game guide content.

Abstract: Delivery devices for delivering an ophthalmic device into an eye. In some embodiments the delivery devices are adapted to deliver an intraocular lens into an eye.

Abstract: The present disclosure relates generally to paddles used in recreational sports. More specifically, this disclosure relates to a pickle ball paddle with a hollow interior adapted/configured to receive and store a liquid within the hollow interior.

Abstract: The present disclosure relates to a positive pressure breathing circuit and a method for ventilating a patient. The breathing circuit can be used in any type of pressurized breathing therapy including, for example, continuous positive air (way) pressure (CPAP) therapy and bilevel positive air pressure therapy where the inspiratory and expiratory pressures differ.

Abstract: A cocrystal having the formula LiX·aM, or a solvate or hydrate thereof, wherein X is a conjugate base of an organic acid, M is a neutral organic molecule, and a is from 0.5 to 4, pharmaceutical compositions comprising such cocrystals, cocrystal solvates, or cocrystal hydrates, and methods of preparing such cocrystals, cocrystal solvates, or cocrystal hydrates, and such pharmaceutical compositions.

Abstract: Interfaces for positive pressure therapy having a mask assembly, a headgear assembly and a connection port assembly are disclosed herein. The connection port assembly has a ball joint connection with the mask assembly and includes a quick release button for easily disconnecting the gases source conduit from the mask assembly. The mask assembly may include a bias flow vent that is formed separately and attached to the mask assembly. The headgear assembly encircles the rear region of the user's head and may include at least some portions that are substantially non-stretchable.

Abstract: Disclosed is a method and apparatus for digital control of a milling machine drum to minimize road material milled using complex geometry. A digital representation of a surface and/or subsurface of a road is loaded into a controller. Road defects are identified based on the digital surface, by comparing defect digital characteristics with the digital surface. A minimum removal map can be generated using the defect digital characteristics. A milling tool path can then be generated to minimize material removal, based on the minimum removal map. The mill depth and movement of a mill drum can then be controlled based on the milling tool path.

Abstract: A conduit for a breathing circuit includes a heater associated, at least in part, with a hydrophilic layer. The purpose of the heater is to evaporate any condensed liquid collecting in the conduit, which is first sucked up by the hydrophilic layer. The heated wick reduces the risk of collected water being passed to the patient and causing choking fits or discomfit. It is preferred that the heated wick lies freely in the conduit to settle at low points in the conduit where condensation may collect.

Abstract: An adjustable part-manufacturing tool and associated systems and methods are disclosed. The adjustable part-manufacturing tool includes a part-receiving receptacle defined by at least a first side and a second side. A first locating detail, including a first locating surface, is movably coupled to the tool body along the first side so that the first locating surface is selectively movable within the part-receiving receptacle in first opposing directions. A second locating detail, including a second locating surface, is movably coupled to the tool body along the second side so that the second locating surface is selectively movable within the part-receiving receptacle in second opposing directions. The second opposing directions are angled relative to the first opposing directions. Selective movement of the first locating surface and the second locating surface accommodates locating parts of different sizes on the first locating surface and the second locating surface within a specified tolerance.

Abstract: The present disclosure generally relates to methods and systems for generating a void profile for user void events. The method includes receiving by a processing element a plurality of outputs from a fluid level sensor corresponding to a plurality of levels of fluid flowing through a voiding device during a flow event; determining by the processing element a beginning and an end time of the fluid flow into the voiding device during the flow event; analyzing the plurality of outputs of the fluid level sensor over a time interval defined by the beginning and end time of the fluid flow to determine at least one of a fluid flow rate data and an accumulated volume data for the fluid flowing through the voiding device; and storing the fluid flow rate data and the accumulated flow volume data in a memory.

Abstract: The present invention relates to stable and low viscosity liquid pharmaceutical compositions comprising antibodies binding to human alpha synuclein and to methods for use of antibodies binding to human alpha synuclein for treating synucleinopathies or prodromal synucleinopathy, incl. suitable doses and/or dosing regimens. These antibodies for use in treatment of synucleinopathies or prodromal synucleinopathy may be formulated in the stable and low viscosity liquid pharmaceutical compositions of the invention.

Abstract: A controller for LiDAR sensor is programmed to activate a plurality of light emitter pairs each including a first light emitter and a second light emitter by alternating between a first powering sequence and a second powering sequence. The first powering sequence includes sequentially activating the first light emitters. The second powering sequence includes sequentially activating the second light emitters. The controller is programmed to, during one of the first powering sequences, detect damage to the first light emitter of a damaged one of the light emitter pairs. The controller is programmed to, during subsequent first powering sequences, activating the second light emitter of the damaged one of the light emitter pairs in response to detected damage to the first light emitter of the damaged one of the light emitter pairs.

Abstract: A respiratory mask can include one or a plurality of force sensors configured to detect a force imparted to a user's skin. Output from the one or more sensors can be represented in a way useful to the patient or healthcare provider for adjusting the mask to achieve a desired fitment. A representation of the detected forces can be displayed on a separate display device or on the mask.

Abstract: A formulation of a single phase solution, including aminopenicillin, a stabilizing agent, and water. The aminopenicillin in the solution has a potency of 87% or higher at 24 hours of storage at room temperature. A formulation of a single phase solution, including amoxicillin, ampicillin, and/or a combination thereof, a stabilizing agent, and water. The amoxicillin, ampicillin, and/or a combination thereof in the solution has a potency of 87% or higher at 24 hours of storage at room temperature. A formulation of a single phase solution, including amoxicillin, a stabilizing agent, and water. The amoxicillin in the solution has a potency of 87% or higher at 24 hours of storage at room temperature. A formulation of a single phase solution, including ampicillin, a stabilizing agent, and water.

Abstract: A dynamic asphalt paver comprising a plurality of gates for distributing the asphalt on the surface of the sub-base, at least one memory, and at least one processor communicatively coupled to the memory(s) and the gates. Each gate is configured to independently change the position relative to the surface and distribute asphalt on the surface based on the position. The processor(s) is configured to: receive a digital model of a portion of the sub-base that is to be paved that includes a plurality of cells that correspond to the portion of the sub-base; compare each cell of the digital model to a corresponding desired cell of a plurality of desired cells of a desired digital model of the portion of the sub-base; and adjust a position of each gate in response to comparing each cell of the digital model to a corresponding desired cell of the desired digital model.