Patents by Inventor John Somberg

John Somberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of initiating or escalating dofetilide dose and formulations therefor
    Patent number: 11957648
    Abstract: The present invention provides a novel method of initiating or escalating dofetilide dosage with the goal of maximizing patient safety while shortening the time period required for electrocardiographic monitoring from three days to one day.
    Type: Grant
    Filed: July 20, 2021
    Date of Patent: April 16, 2024
    Assignee: HYLORIS DEVELOPMENTS S.A.
    Inventor: John Somberg
  • ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS
    Publication number: 20240025846
    Abstract: Some aspects provide novel dofetilide derivatives and pharmaceutical compositions containing the same that are useful as pharmaceutical agents in the treatment of supraventricular and ventricular arrhythmias.
    Type: Application
    Filed: July 6, 2023
    Publication date: January 25, 2024
    Inventors: John Somberg, Robert J. Chorvat
  • Ultra short acting anti-arrhythmic agents
    Patent number: 11731938
    Abstract: Some aspects provide novel dofetilide derivatives and pharmaceutical compositions containing the same that are useful as pharmaceutical agents in the treatment of supraventricular and ventricular arrhythmias.
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: August 22, 2023
    Assignee: Academic Pharmaceuticals Inc
    Inventors: John Somberg, Robert J Chorvat
  • Method of initiating and escalating sotalol hydrochloride dosing
    Patent number: 11696902
    Abstract: This disclosure provides a method of safely and rapidly initiating or escalating oral sotalol therapy by administering an intravenous dosage of sotalol followed by oral sotalol twice daily.
    Type: Grant
    Filed: November 24, 2019
    Date of Patent: July 11, 2023
    Assignee: AltaThera Pharmaceuticals, LLC
    Inventors: John Somberg, Brandon Ira Kashfian, Janos Molnar
  • SOTALOL HYDROCHLORIDE DOSING
    Publication number: 20220241225
    Abstract: The present invention provides novel methods of administering sotalol hydrochloride to patients in need thereof.
    Type: Application
    Filed: April 20, 2022
    Publication date: August 4, 2022
    Inventor: John Somberg
  • ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS
    Publication number: 20220213032
    Abstract: Some aspects provide novel dofetilide derivatives and pharmaceutical compositions containing the same that are useful as pharmaceutical agents in the treatment of supraventricular and ventricular arrhythmias.
    Type: Application
    Filed: December 22, 2021
    Publication date: July 7, 2022
    Inventors: John Somberg, Robert J Chorvat
  • Method of initiating or escalating dofetilide dose and formulations therefor
    Patent number: 11364213
    Abstract: The present invention provides a novel method of initiating or escalating dofetliide dosage with the goal of maximizing patient safety while shortening the time period required for electrocardiographic monitoring from three days to one day.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: June 21, 2022
    Assignee: Academic Pharmaceuticals Inc
    Inventor: John Somberg
  • Method of converting atrial fibrillation to normal sinus rhythm and loading oral sotalol in a shortened time frame
    Patent number: 11344518
    Abstract: The present invention provides a novel method of converting AF and monitoring normal sinus rhythm using an initial IV dose of sotalol followed by oral sotalol maintenance therapy. This method provides a method of acute assessment of QTc prolongation to determine the safety of chronic oral sotalol therapy and reduces the hospitalization stay required for conversion and sotalol initiation.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: May 31, 2022
    Assignee: AltaThera Pharmaceuticals LLC
    Inventor: John Somberg
  • METHOD OF INITIATING AND ESCALATING SOTALOL HYDROCHLORIDE DOSING
    Publication number: 20220142954
    Abstract: The present invention provides novel methods of initiating and escalating sotalol hydrochloride in patients in need thereof.
    Type: Application
    Filed: January 26, 2022
    Publication date: May 12, 2022
    Inventor: John Somberg
  • Ultra short acting anti-arrhythmic agents
    Patent number: 11286235
    Abstract: The present invention provides novel sotalol derivatives and pharmaceutical compositions containing the same that are are useful as pharmaceutical agents in the treatment of supraventricular and ventricular arrhythmias.
    Type: Grant
    Filed: October 5, 2020
    Date of Patent: March 29, 2022
    Assignee: Academic Pharmaceuticals, Incorporated
    Inventors: John Somberg, Robert J Chorvat
  • METHOD OF INITIATING OR ESCALATING DOFETILIDE DOSE AND FORMULATIONS THEREFOR
    Publication number: 20210346325
    Abstract: The present invention provides a novel method of initiating or escalating dofetilide dosage with the goal of maximizing patient safety while shortening the time period required for electrocardiographic monitoring from three days to one day.
    Type: Application
    Filed: July 20, 2021
    Publication date: November 11, 2021
    Inventor: John Somberg
  • INTRAVENOUS SOTALOL HYDROCHLORIDE LOADING AND MAINTENANCE FOR CARDIAC SURGERY PATIENTS
    Publication number: 20210283049
    Abstract: The present invention provides a novel intravenous, prophylactic, antiarrhythmic method of sotalol loading and maintenance for cardiothoracic surgery patients.
    Type: Application
    Filed: May 3, 2021
    Publication date: September 16, 2021
    Inventor: John Somberg
  • ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS
    Publication number: 20210107867
    Abstract: The present invention provides novel sotalol derivatives and pharmaceutical compositions containing the same that are are useful as pharmaceutical agents in the treatment of supraventricular and ventricular arrhythmias.
    Type: Application
    Filed: October 5, 2020
    Publication date: April 15, 2021
    Inventors: John Somberg, Robert J Chorvat
  • METHOD OF CONVERTING ATRIAL FIBRILLATION TO NORMAL SINUS RHYTHM AND LOADING ORAL SOTALOL IN A SHORTENED TIME FRAME
    Publication number: 20200338027
    Abstract: The present invention provides a novel method of converting AF and monitoring normal sinus rhythm using an initial IV dose of sotalol followed by oral sotalol maintenance therapy. This method provides a method of acute assessment of QTc prolongation to determine the safety of chronic oral sotalol therapy and reduces the hospitalization stay required for conversion and sotalol initiation.
    Type: Application
    Filed: July 13, 2020
    Publication date: October 29, 2020
    Inventor: John Somberg
  • Ultra short acting anti-arrhythmic agents
    Patent number: 10793519
    Abstract: The present invention provides novel sotalol derivatives and pharmaceutical compositions containing the same that are are useful as pharmaceutical agents in the treatment of supraventricular and ventricular arrhythmias.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: October 6, 2020
    Assignee: Academic Pharmaceuticals Incorporated
    Inventors: John Somberg, Robert J Chorvat
  • METHOD OF INITIATING AND ESCALATING SOTALOL HYDROCHLORIDE DOSING
    Publication number: 20200253903
    Abstract: The present invention provides novel methods of initiating and escalating sotalol hydrochloride in patients in need thereof.
    Type: Application
    Filed: April 30, 2020
    Publication date: August 13, 2020
    Inventor: John Somberg
  • METHOD OF INITIATING OR ESCALATING DOFETILIDE DOSE AND FORMULATIONS THEREFOR
    Publication number: 20190388371
    Abstract: The present invention provides a novel method of initiating or escalating dofetliide dosage with the goal of maximizing patient safety while shortening the time period required for electrocardiographic monitoring from three days to one day.
    Type: Application
    Filed: June 24, 2019
    Publication date: December 26, 2019
    Inventor: John Somberg
  • ULTRA SHORT ACTING ANTI-ARRHYTHMIC AGENTS
    Publication number: 20190352257
    Abstract: The present invention provides novel sotalol derivatives and pharmaceutical compositions containing the same that are are useful as pharmaceutical agents in the treatment of supraventricular and ventricular arrhythmias.
    Type: Application
    Filed: April 30, 2019
    Publication date: November 21, 2019
    Inventors: John Somberg, Robert J Chorvat
  • Parenteral solutions containing metolazone
    Patent number: 9427398
    Abstract: Disclosed herein are parenteral solutions containing 7-halo-1,2,3,4-tetrahydro-3-aryl-6-quinazoline sulfonamide in N,N-dimethylacetamide, polyethylene glycol and D5W useful in the treatment of hypertension, heart failure and renal disease leading to edematous states. Also disclosed are methods for preparing such solutions.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: August 30, 2016
    Assignee: Academic Pharmaceuticals Incorporated
    Inventors: John Somberg, Vasant Ranade
  • THROMBOSIS WARNING SYSTEM
    Publication number: 20130190621
    Abstract: The present invention relates to a device for detecting the potential formation of a thrombus in a patient on a ventricular assist device. The device uses an energy source and sensor to detect changes in rheology of the patient.
    Type: Application
    Filed: July 27, 2012
    Publication date: July 25, 2013
    Applicant: ACADEMIC PHARMACEUTICALS INCORPORATED
    Inventor: John Somberg