Patents by Inventor John Spaltro
John Spaltro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7829109Abstract: Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions have substantially improved shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.Type: GrantFiled: November 14, 2002Date of Patent: November 9, 2010Assignee: Durect CorporationInventors: Guohua Chen, Paul R. Houston, Lothar Kleiner, John Spaltro
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Publication number: 20070179595Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.Type: ApplicationFiled: April 17, 2007Publication date: August 2, 2007Inventors: Luis Davila, David Lentz, Gerard Llanos, Jorge Mendez, Pallassana Narayanan, Alan Pelton, Mark Roller, Karl Scheidt, Angelo Scopelianos, William Shaw, James Silver, John Spaltro, Christine Trepanier, David Wilson
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Publication number: 20070179597Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.Type: ApplicationFiled: April 17, 2007Publication date: August 2, 2007Inventors: Luis Davila, David Lentz, Gerard Llanos, Jorge Mendez, Pallassana Narayanan, Alan Pelton, Mark Roller, Karl Scheidt, Angelo Scopelianos, William Shaw, James Silver, John Spaltro, Christine Trepanier, David Wilson
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Publication number: 20070179596Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.Type: ApplicationFiled: April 17, 2007Publication date: August 2, 2007Inventors: Luis Davila, David Lentz, Gerard Llanos, Jorge Mendez, Pallassana Narayanan, Alan Pelton, Mark Roller, Karl Scheidt, Angelo Scopelianos, William Shaw, James Silver, John Spaltro, Christine Trepanier, David Wilson
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Patent number: 7195640Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. In addition to reducing or substantially eliminating a biological organism's reaction to the introduction of the medical device to the organism, the medical device in combination with one or more therapeutic drugs, agents and/or compounds may be utilized to treat various vascular diseases, for example, restenosis and vulnerable plaque.Type: GrantFiled: April 15, 2002Date of Patent: March 27, 2007Assignee: Cordis CorporationInventors: Robert Falotico, John Spaltro
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Publication number: 20060222756Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.Type: ApplicationFiled: May 19, 2006Publication date: October 5, 2006Applicant: Cordis CorporationInventors: Luis Davila, David Lentz, Gerard Llanos, Jorge Mendez, Pallassana Narayanan, Alan Pelton, Mark Roller, Karl Scheidt, Angelo Scopelianos, William Shaw, James Silver, John Spaltro, Christine Trepanier, David Wilson
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Patent number: 7056550Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.Type: GrantFiled: August 7, 2003Date of Patent: June 6, 2006Assignee: Ethicon, Inc. - USAInventors: Luis A. Davila, David Christian Lentz, Gerard H. Llanos, Jorge Orlando Mendez, Pallassana V. Narayanan, Alan Roy Pelton, Mark B. Roller, Karl K. Scheidt, Angelo George Scopelianos, William Douglas Shaw, Jr., James H. Silver, John Spaltro, Christine Trepanier, David J. Wilson
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Publication number: 20040102758Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.Type: ApplicationFiled: August 7, 2003Publication date: May 27, 2004Inventors: Luis A. Davila, David Christian Lentz, Gerard H. Llanos, Jorge Orlando Mendez, Pallassana V. Narayanan, Alan Roy Pelton, Mark B. Roller, Karl K. Scheidt, Angelo George Scopelianos, William Douglas Shaw, James H. Silver, John Spaltro, Christine Trepanier, David J. Wilson
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Publication number: 20040002755Abstract: A drug-eluting intravascular stent comprising an anti-restenosis agent covered by a biodegradable coating, and a method for treating vulnerable plaque in coronary vessels using said stent is disclosed. The biodegradable layer covers at least a portion of the drug-eluting layer of the stent, and is adapted to slowly erode over a preset period of time, preventing the release of therapeutic amounts of the anti-restenosis agent from the drug-eluting layer during the preset period. By delaying the release of the anti-restenosis agent, a thin layer of neointima will grow during the preset period. This tissue growth is sufficient to encapsulate the stent and cover the vulnerable plaque, but not significant enough to cause harmful restenosis or occlusion of the vessel. Once the biodegradable coating is eroded, the anti-restenosis agent begins release from the drug-eluting layer, and the progression of neointimal hyperplasia ceases.Type: ApplicationFiled: June 28, 2002Publication date: January 1, 2004Inventors: David R. Fischell, John Spaltro
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Publication number: 20030180364Abstract: Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions are have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.Type: ApplicationFiled: November 14, 2002Publication date: September 25, 2003Inventors: Guohua Chen, Paul R. Houston, Lothar Kleiner, John Spaltro
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Publication number: 20030060877Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. In addition to reducing or substantially eliminating a biological organism's reaction to the introduction of the medical device to the organism, the medical device in combination with one or more therapeutic drugs, agents and/or compounds may be utilized to treat various vascular diseases, for example, restenosis and vulnerable plaque.Type: ApplicationFiled: April 15, 2002Publication date: March 27, 2003Inventors: Robert Falotico, John Spaltro
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Publication number: 20020111590Abstract: Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. Various materials and coating methodologies may be utilized to maintain the drugs, agents or compounds on the medical device until delivered and positioned.Type: ApplicationFiled: September 25, 2001Publication date: August 15, 2002Inventors: Luis A. Davila, David Christian Lentz, Gerard H. Llanos, Jorge Orlando Mendez, Pallassana V. Narayanan, Alan Roy Pelton, Mark B. Roller, Karl K. Scheidt, Angelo George Scopelianos, William Douglas Shaw, James H. Silver, John Spaltro, Christine Trepanier, David J. Wilson