Abstract: The invention relates to the introduction of pressurized fluid, e.g. acid, into a subsea well directly from a vessel (33). A fluid injection assembly (20) is fitted to the top of a subsea Xmas tree (3), the assembly (20) including fail safe closed valve (21) which is controlled via a hydraulic line (31) from the vessel. The hose and assembly and valve are designed with an internal bore allowing a large diameter ball to be dropped (required for acid stimulation). The subsea subsea control module (8) on the Xmas tree is controlled from the producing platform.

Abstract: The invention relates to the introduction of pressurized fluid, e.g. acid, into a subsea well directly from a vessel (33). A fluid injection assembly (20) is fitted to the top of a subsea Xmas tree (3), the assembly (20) including fail safe closed valve (21) which is controlled via a hydraulic line (31) from the vessel. The hose and assembly and valve are designed with an internal bore allowing a large diameter ball to be dropped (required for acid stimulation). The subsea subsea control module (8) on the Xmas tree is controlled from the producing platform.

Abstract: A microfluidic device for use in a serial crystallography apparatus includes a modular 3D-printed nozzle having an inlet, an outlet, and a first snap engagement feature. The microfluidic device further includes a modular 3D-printed fiber holder having an outlet and a second snap engagement feature. The first snap engagement feature is configured to engage the second snap engagement feature to removably couple the nozzle to the fiber holder. The outlet of the fiber holder is aligned with the inlet of the nozzle when the first snap engagement feature is coupled to the second snap engagement feature.

Abstract: A microfluidic device for use in a serial crystallography apparatus includes a nozzle having an inlet, an outlet, and a first snap engagement feature. The microfluidic device further includes a fiber holder having an outlet and a second snap engagement feature. The first snap engagement feature is configured to engage the second snap engagement feature to removably couple the nozzle to the fiber holder. The outlet of the fiber holder is aligned with the inlet of the nozzle when the first snap engagement feature is coupled to the second snap engagement feature.

Abstract: The invention relates to the introduction of pressurized fluid, e.g. acid, into a subsea well directly from a vessel (33). A fluid injection assembly (20) is fitted to the top of a subsea Xmas tree (3), the assembly (20) including fail safe closed valve (21) which is controlled via a hydraulic line (31) from the vessel. The hose and assembly and valve are designed with an internal bore allowing a large diameter ball to be dropped (required for acid stimulation). The subsea subsea control module (8) on the Xmas tree is controlled from the producing platform.

Abstract: A 3D printed hybrid nozzle device combining a microfluidic mixer with a liquid jet injector that addresses the bottleneck of investigating substrate-initiated biological reaction paths employing serial crystallography with XFELs. The hybrid nozzle provides for injecting aqueous protein crystal jets after fast mixing (<5 ms), reaching reaction time points (e.g., about 10 ms to about 150 ms) suitable to resolve enzyme kinetics.

Abstract: An individualized preoperative planning system for fracture fixation constructs provides fracture assessment before automatically performing finite element simulations to generate biomechanics associated with a large number of fracture fixation construct design alternatives. Data visualization utilizing multivariate plots or surrogate modeling based on the simulation results are then provided to surgeons enabling surgeons to view, adjust and optimize their fracture fixation construct designs.

Abstract: A 3D printed hybrid nozzle device combining a microfluidic mixer with a liquid jet injector that addresses the bottleneck of investigating substrate-initiated biological reaction paths employing serial crystallography with XFELs. The hybrid nozzle provides for injecting aqueous protein crystal jets after fast mixing (<5 ms), reaching reaction time points (e.g., about 10 ms to about 150 ms) suitable to resolve enzyme kinetics.

Abstract: Nozzle Assemblies and methods of use for producing a liquid jet are disclosed that may be permit adjustable time delays between mixing of fluids and observation of reactions. An example nozzle assembly includes: a housing having an inlet and an outlet and a first channel defined therebetween, where the housing includes a gas focusing aperture defining the housing outlet; an intermediate tube disposed within the first channel of the housing, where the intermediate tube has an inlet and an outlet and defines a second channel therebetween; and a central tube disposed within the second channel of the intermediate tube, where the central tube has an inlet and an outlet and defines a third channel therebetween, where the central tube outlet is longitudinally spaced apart from the intermediate tube outlet such that the intermediate tube outlet is disposed between the central tube outlet and the gas focusing aperture's inlet.

Abstract: A system enables network-based systems to confirm the identity of users and/or the authenticity of their credentials during their registration process by providing a database of verified users and various means for requesting and verifying user-provided information using the database. For example, the system may verify credentials and/or other aspects of the user and store such information in a database. The system may also generate badges that can be displayed on various content sites and that link to a summary of the user's verified information. The summaries may be customized for each content site at which the user has registered.

Abstract: An individualized preoperative planning system for fracture fixation constructs provides fracture assessment before automatically performing finite element simulations to generate biomechanics associated with a large number of fracture fixation construct design alternatives. Data visualization utilizing multivariate plots or surrogate modeling based on the simulation results are then provided to surgeons enabling surgeons to view, adjust and optimize their fracture fixation construct designs.

Abstract: An injector apparatus and methods for use, where the injector apparatus comprises: (a) hydraulic stage having first and second ends and including a housing defining a cavity, a primary plunger disposed in the cavity and a secondary plunger, (b) a pressurization system coupled to the hydraulic stage's first end, where the primary plunger is in fluid communication with the pressurization system and is in mechanical communication with the secondary plunger, (c) a reservoir bore defined in the hydraulic stage housing and configured to receive the primary plunger's second end, where the secondary plunger is disposed within the reservoir bore and (d) a nozzle assembly including a housing, a gas tube and a nozzle capillary, where the nozzle capillary is partially disposed in and is substantially coaxial with the gas tube, where the nozzle capillary's first end is in fluid communication with the reservoir bore's second end.

Abstract: Nozzle Assemblies and methods of use for producing a liquid jet are disclosed that may be permit adjustable time delays between mixing of fluids and observation of reactions. An example nozzle assembly includes: a housing having an inlet and an outlet and a first channel defined therebetween, where the housing includes a gas focusing aperture defining the housing outlet; an intermediate tube disposed within the first channel of the housing, where the intermediate tube has an inlet and an outlet and defines a second channel therebetween; and a central tube disposed within the second channel of the intermediate tube, where the central tube has an inlet and an outlet and defines a third channel therebetween, where the central tube outlet is longitudinally spaced apart from the intermediate tube outlet such that the intermediate tube outlet is disposed between the central tube outlet and the gas focusing aperture's inlet.

Abstract: A system is disclosed that enables network-based systems to confirm the identity of users and/or the authenticity of their credentials during their registration process by providing a database of verified users and various means for requesting and verifying user-provided information using the database. For example, the system may verify credentials and/or other aspects of the user and store such information in a database. The system may also generate badges that can be displayed on various content sites and that link to a summary of the user's verified information. The summaries may be customized for each content site at which the user has registered.

Abstract: A system is disclosed that enables network-based systems to confirm the identity of users and/or the authenticity of their credentials during their registration process by providing a database of verified users and various means for requesting and verifying user-provided information using the database. For example, the system may verify credentials and/or other aspects of the user and store such information in a database. The system may also generate badges that can be displayed on various content sites and that link to a summary of the user's verified information. The summaries may be customized for each content site at which the user has registered.

Abstract: A nozzle for producing a liquid jet or a single-file stream of droplets of a fluid, methods using the nozzle, and an injector comprising the nozzle of the invention for providing the liquid jet or single-file stream of a fluid to a vacuum system are described.

Abstract: An injector apparatus and methods for use, where the injector apparatus comprises: (a) hydraulic stage having first and second ends and including a housing defining a cavity, a primary plunger disposed in the cavity and a secondary plunger, (b) a pressurization system coupled to the hydraulic stage's first end, where the primary plunger is in fluid communication with the pressurization system and is in mechanical communication with the secondary plunger, (c) a reservoir bore defined in the hydraulic stage housing and configured to receive the primary plunger's second end, where the secondary plunger is disposed within the reservoir bore and (d) a nozzle assembly including a housing, a gas tube and a nozzle capillary, where the nozzle capillary is partially disposed in and is substantially coaxial with the gas tube, where the nozzle capillary's first end is in fluid communication with the reservoir bore's second end.

Abstract: An X-ray optical device includes a crystal containing a channel, which passes through the crystal and has multiple internal faces. A mount is configured to hold the crystal in a fixed location relative to a source of an X-ray beam and to shift the crystal automatically between two predefined dispositions: a first disposition in which the X-ray beam passes through the channel while diffracting from one or more of the internal faces, and a second disposition in which the X-ray beam passes through the channel without diffraction by the crystal.

Abstract: A nozzle for producing a liquid jet a fluid, methods using the nozzle, and an injector comprising the nozzle of the invention for providing the liquid jet of a fluid to a vacuum system are described.