Patents by Inventor John Squires
John Squires has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11807671Abstract: The invention relates to protein ligation technologies, purified or recombinant peptides, methods for making peptides and proteins with covalent bonds including reversible covalent bonds such as reversible intermolecular covalent bonds, and uses thereof. In particular, this invention relates to intermolecular ester bonds, particularly reversible ester bonds between the hydroxyl and amide groups of amino acid side chains present in recombinant chimeric peptides and proteins and the use of such peptides and proteins in protein engineering, for example in the preparation of multimeric protein complexes, including functionalised multimeric protein complexes.Type: GrantFiled: November 16, 2017Date of Patent: November 7, 2023Assignee: AUCKLAND UNISERVICES LIMITEDInventors: Christopher John Squire, Edward Neill Baker, Paul Gary Young, Yuliana Yosaatmadja
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Publication number: 20230219384Abstract: A tire lever head physically adapted to couple to an end of a 16-gram or 25-gram CO2 cartridge, but to not pierce the CO2 cartridge. Rather than using the CO2 cartridge for its nominally intended purpose of inflating a tire or tube, the tire-lever head functions as the handle portion of a tire lever. That is, the CO2 cartridge is gripped by a user, and is manipulated to apply the force that is required for tire removal/installation.Type: ApplicationFiled: January 10, 2023Publication date: July 13, 2023Inventor: John Squires SMITH
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Patent number: 11612997Abstract: A bicycle workstation that is removably suspended in a doorway when in use includes several elongate members that collectively provide at least three contact surfaces, and an additional elongate member that, in the illustrative embodiment, couples to a clamp suitable for clamping to a part of a bicycle. The contact surfaces are arranged such that the weight of the bicycle forces them against a wall, door frame, and moulding on both sides of the doorway, thereby securely suspending the bicycle workstation, and the bicycle clamped to it.Type: GrantFiled: May 8, 2020Date of Patent: March 28, 2023Assignee: The Bike Hangar LLCInventor: John Squires Smith
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Publication number: 20220033377Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: November 2, 2020Publication date: February 3, 2022Applicant: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Patent number: 11192890Abstract: Fibroblast Growth Factor Receptor kinase inhibitors and prodrugs thereof of Formula (I) and their use for the treatment of hyper-proliferative diseases such as retinopathy, psoriasis, rheumatoid arthritis, osteoarthritis, septic arthritis, tumour metastasis, periodontal disease, corral ulceration, proteinuria, coronary thrombosis from atherosclerotic plaque, aneurismal aorta, dystrophobic epidermolysis bullosa, degenerative cartilage loss following traumatic joint injury, osteopenias mediated by MMP activity, tempero mandibular joint disease, and demyelating disease of the nervous system.Type: GrantFiled: March 2, 2018Date of Patent: December 7, 2021Assignees: AUCKLAND UNISERVICES LIMITED, GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTHInventors: Adam Vorn Patterson, Jeffrey Bruce Smaill, Amir Ashoorzadeh, Christopher Paul Guise, Christopher John Squire, Swarnalatha Akuratiya Gamage, Maria Rosaria Abbattista, Matthew Roy Bull, Angus Cheverton Grey, Xueqiang Li, Ke Ding, Xiaomei Ren, Shuang Jiang, Zhengchao Tu
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Publication number: 20200353611Abstract: A bicycle workstation that is removably suspended in a doorway when in use includes several elongate members that collectively provide at least three contact surfaces, and an additional elongate member that, in the illustrative embodiment, couples to a clamp suitable for clamping to a part of a bicycle. The contact surfaces are arranged such that the weight of the bicycle forces them against a wall, door frame, and moulding on both sides of the doorway, thereby securely suspending the bicycle workstation, and the bicycle clamped to it.Type: ApplicationFiled: May 8, 2020Publication date: November 12, 2020Inventor: John Squires SMITH
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Publication number: 20200017491Abstract: Fibroblast Growth Factor Receptor kinase inhibitors and prodrugs thereof of Formula (I) and their use for the treatment of hyper-proliferative diseases such as retinopathy, psoriasis, rheumatoid arthritis, osteoarthritis, septic arthritis, tumour metastasis, periodontal disease, corral ulceration, proteinuria, coronary thrombosis from atherosclerotic plaque, aneurismal aorta, dystrophobic epidermolysis bullosa, degenerative cartilage loss following traumatic joint injury, osteopenias mediated by MMP activity, tempero mandibular joint disease, and demyelating disease of the nervous system.Type: ApplicationFiled: March 2, 2018Publication date: January 16, 2020Applicants: Auckland Uniservices Limited, Guangzhou Intitute of BioMedicine and HealthInventors: Adam Vorn PATTERSON, Jeffrey Bruce SMAILL, Amir ASHOORZADEH, Christopher Paul GUISE, Christopher John SQUIRE, Swarnalatha Akuratiya GAMAGE, Maria Rosaria ABBATTISTA, Matthew Roy BULL, Angus Cheverton GREY, Xueqiang LI, Ke DING, Xiaomei REN, Shuang JIANG, Zhengchao TU
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Publication number: 20190352343Abstract: The invention relates to protein ligation technologies, purified or recombinant peptides, methods for making peptides and proteins with covalent bonds including reversible covalent bonds such as reversible intermolecular covalent bonds, and uses thereof. In particular, this invention relates to intermolecular ester bonds, particularly reversible ester bonds between the hydroxyl and amide groups of amino acid side chains present in recombinant chimeric peptides and proteins and the use of such peptides and proteins in protein engineering, for example in the preparation of multimeric protein complexes, including functionalised multimeric protein complexes.Type: ApplicationFiled: November 16, 2017Publication date: November 21, 2019Inventors: Christopher John SQUIRE, Edward Neill BAKER, Paul Gary YOUNG, Yuliana YOSAATMADJA
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Publication number: 20190263782Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: May 8, 2019Publication date: August 29, 2019Applicant: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Patent number: 10344015Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilizing said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: GrantFiled: October 27, 2017Date of Patent: July 9, 2019Assignee: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Publication number: 20180118716Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: October 27, 2017Publication date: May 3, 2018Applicant: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Patent number: 9815816Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilizing said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: GrantFiled: July 22, 2015Date of Patent: November 14, 2017Assignee: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Patent number: 9562017Abstract: The present invention relates to Compound 1 hydrogen sulfate salt and solvates, crystalline forms and amorphous forms thereof, and to processes for their preparation.Type: GrantFiled: April 28, 2015Date of Patent: February 7, 2017Assignees: AsrtaZeneca AB, Array BioPharma Inc.Inventors: John DeMattei, Tsung-Hsun Chuang, Gorkhn Sharma-Singh, Paul Alfred Dickinson, Mohammed Pervez, Richard Anthony Storey, Christopher John Squire, James Gair Ford, Ronald John Roberts
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Patent number: 9510127Abstract: A method of providing an audio signal comprising spatial information relating to a location of at least one virtual source (202) in a sound field with respect to a first user position comprises obtaining a first audio signal comprising a plurality of signal components, each of the signal components corresponding to a respective one of a plurality of virtual loudspeakers (200a-e) located in the sound field; obtaining an indication of user movement; determining a plurality of panned signal components by applying, in accordance with the indication of user movement, a panning function of a respective order to each of the signal components; and outputting a second audio signal comprising the panned signal components.Type: GrantFiled: June 27, 2013Date of Patent: November 29, 2016Assignee: Google Inc.Inventors: John Squires, Marcin Gorzel, Ian Kelly, Frank Boland
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Publication number: 20160185754Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: July 22, 2015Publication date: June 30, 2016Applicant: ASTRAZENECA ABInventors: Jorgen BLIXT, Michael David GOLDEN, Philip John HOGAN, David Michael Glanville MARTIN, Francis Joseph MONTGOMERY, Zakariya PATEL, John David PITTAM, George Joseph SEPENDA, Christopher John SQUIRE, Nicholas Cartwright Alexander WRIGHT
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Publication number: 20160024018Abstract: The present invention relates to Compound 1 hydrogen sulfate salt and solvates, crystalline forms and amorphous forms thereof, and to processes for their preparation.Type: ApplicationFiled: April 28, 2015Publication date: January 28, 2016Inventors: John DeMattei, Tsung-Hsun Chuang, Gorkhn Sharma-Singh, Paul Alfred Dickinson, Mohammed Pervez, Richard Anthony Storey, Christopher John Squire, James Gair Ford, Ronald John Roberts
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Patent number: 9156795Abstract: The present invention relates to Compound 1 hydrogen sulfate salt and solvates, crystalline forms and amorphous forms thereof, and to processes for their preparation.Type: GrantFiled: May 3, 2012Date of Patent: October 13, 2015Assignees: Array BioPharma, Inc., Astrazeneca ABInventors: John DeMattei, Tsung-Hsun Chuang, Christopher John Squire, Ronald John Roberts, Gorkhn Sharma-Singh, Mohammed Pervez, James Gair Ford, Richard Anthony Storey, Paul Alfred Dickinson
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Patent number: D1016630Type: GrantFiled: April 18, 2022Date of Patent: March 5, 2024Assignee: Illumagear, Inc.Inventors: Matt Squires, Jedediah Joaquin McCann, Joshua Robert Buesseler, Kyle Visner, Ben Salinas, Chester Macklin, George Harris, John Maxwell Baker
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Patent number: D1016631Type: GrantFiled: April 18, 2022Date of Patent: March 5, 2024Assignee: Illumagear, Inc.Inventors: Matt Squires, Jedediah Joaquin McCann, Joshua Robert Buesseler, John Maxwell Baker
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Patent number: D1019425Type: GrantFiled: April 18, 2022Date of Patent: March 26, 2024Assignee: Illumagear, Inc.Inventors: Matt Squires, Jedediah Joaquin McCann, Joshua Robert Buesseler, John Maxwell Baker