Patents by Inventor John Stark
John Stark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11866766Abstract: A system and method for target material capture, the method comprising: receiving a set of target cells into an array of wells defined at a surface plane of a substrate; receiving a set of particles into the array of wells, thereby co-capturing the set of target cells and the set of particles; achieving a desired state for the array of wells upon receiving a washing fluid into a cavity in communication with the array of wells; receiving a lysis buffer into the cavity; receiving a partitioning fluid into the cavity, thereby displacing the lysis buffer from the cavity and partitioning each of the array of wells from adjacent wells, at the surface plane; and retaining intercellular material of the set of target cells, individually with the set of particles within the array of wells.Type: GrantFiled: October 21, 2022Date of Patent: January 9, 2024Assignee: Bio-Rad Laboratories, Inc.Inventors: Kalyan Handique, John Stark, Yadwinder Deol, Vishal Sharma
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Publication number: 20230407372Abstract: A system and method for target material capture, the method comprising: receiving a set of target cells into an array of wells defined at a surface plane of a substrate; receiving a set of particles into the array of wells, thereby co-capturing the set of target cells and the set of particles; achieving a desired state for the array of wells upon receiving a washing fluid into a cavity in communication with the array of wells; receiving a lysis buffer into the cavity; receiving a partitioning fluid into the cavity, thereby displacing the lysis buffer from the cavity and partitioning each of the array of wells from adjacent wells, at the surface plane; and retaining intercellular material of the set of target cells, individually with the set of particles within the array of wells.Type: ApplicationFiled: September 6, 2023Publication date: December 21, 2023Inventors: Kalyan Handique, John Stark, Yadwinder Deol, Vishal Sharma
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Patent number: 11814671Abstract: A system and method for target material capture, the method comprising: receiving a set of target cells into an array of wells defined at a surface plane of a substrate; receiving a set of particles into the array of wells, thereby co-capturing the set of target cells and the set of particles; achieving a desired state for the array of wells upon receiving a washing fluid into a cavity in communication with the array of wells; receiving a lysis buffer into the cavity; receiving a partitioning fluid into the cavity, thereby displacing the lysis buffer from the cavity and partitioning each of the array of wells from adjacent wells, at the surface plane; and retaining intercellular material of the set of target cells, individually with the set of particles within the array of wells.Type: GrantFiled: February 8, 2021Date of Patent: November 14, 2023Assignee: Bio-Rad Laboratories, Inc.Inventors: Kalyan Handique, John Stark, Yadwinder Deol, Vishal Sharma
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Publication number: 20230056356Abstract: A system and method for target material capture, the method comprising: receiving a set of target cells into an array of wells defined at a surface plane of a substrate; receiving a set of particles into the array of wells, thereby co-capturing the set of target cells and the set of particles; achieving a desired state for the array of wells upon receiving a washing fluid into a cavity in communication with the array of wells; receiving a lysis buffer into the cavity; receiving a partitioning fluid into the cavity, thereby displacing the lysis buffer from the cavity and partitioning each of the array of wells from adjacent wells, at the surface plane; and retaining intercellular material of the set of target cells, individually with the set of particles within the array of wells.Type: ApplicationFiled: October 21, 2022Publication date: February 23, 2023Inventors: Kalyan Handique, John Stark, Yadwinder Deol, Vishal Sharma
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Patent number: 11439143Abstract: A temperature sensor for monitoring an organ or tissue is configured to measure a temperature inside of a container configured to contain the organ or tissue. The temperature sensor is disposed exterior to the organ container and the temperature sensor is a non-contact temperature sensor. The temperature sensor may be part of an apparatus for perfusing, transporting, and/or storing an organ or tissue. A coolant container may have an aperture through which the temperature sensor measures a temperature of at least one of the organ or tissue or a perfusate fluid surrounding the organ or tissue. The temperature sensor is preferably an infrared temperature sensor. Multiple temperature sensors may be provided that measure the temperature organ or tissue or perfusate fluid surrounding the organ or tissue, for example in case one of the temperature sensors fails.Type: GrantFiled: July 10, 2012Date of Patent: September 13, 2022Assignee: LIFELINE SCIENTIFIC, INC.Inventors: David Kravitz, Christopher P. Steinman, David Pettinato, Richard K. Buck, John Stark, Robert J. Allen
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Patent number: 11298010Abstract: Disclosed herein are devices having both imaging components and cell collection apparatuses. More specifically, the various embodiments disclosed herein include swallowable capsules having deployable collection structures, expansion structures to deploy the collection structures, and imaging components.Type: GrantFiled: January 31, 2018Date of Patent: April 12, 2022Assignees: University of Kansas, Department of Veterans AffairsInventors: Ajay Bansal, Lane Christenson, Nick Baker, Ryan Baskins, John Stark, Nourouddin Sharifi, Hadi Kh A Kh Alzuabi, Parker Gill
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Publication number: 20210164023Abstract: A system and method for target material capture, the method comprising: receiving a set of target cells into an array of wells defined at a surface plane of a substrate; receiving a set of particles into the array of wells, thereby co-capturing the set of target cells and the set of particles; achieving a desired state for the array of wells upon receiving a washing fluid into a cavity in communication with the array of wells; receiving a lysis buffer into the cavity; receiving a partitioning fluid into the cavity, thereby displacing the lysis buffer from the cavity and partitioning each of the array of wells from adjacent wells, at the surface plane; and retaining intercellular material of the set of target cells, individually with the set of particles within the array of wells.Type: ApplicationFiled: February 8, 2021Publication date: June 3, 2021Inventors: Kalyan Handique, John Stark, Yadwinder Deol, Vishal Sharma
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Patent number: 10947581Abstract: A system and method for target material capture, the method comprising: receiving a set of target cells into an array of wells defined at a surface plane of a substrate; receiving a set of particles into the array of wells, thereby co-capturing the set of target cells and the set of particles; achieving a desired state for the array of wells upon receiving a washing fluid into a cavity in communication with the array of wells; receiving a lysis buffer into the cavity; receiving a partitioning fluid into the cavity, thereby displacing the lysis buffer from the cavity and partitioning each of the array of wells from adjacent wells, at the surface plane; and retaining intercellular material of the set of target cells, individually with the set of particles within the array of wells.Type: GrantFiled: March 17, 2020Date of Patent: March 16, 2021Assignee: Bio-Rad Laboratories, Inc.Inventors: Kalyan Handique, John Stark, Yadwinder Deol, Vishal Sharma
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Publication number: 20200332347Abstract: A system and method for target material capture, the method comprising: receiving a set of target cells into an array of wells defined at a surface plane of a substrate; receiving a set of particles into the array of wells, thereby co-capturing the set of target cells and the set of particles; achieving a desired state for the array of wells upon receiving a washing fluid into a cavity in communication with the array of wells; receiving a lysis buffer into the cavity; receiving a partitioning fluid into the cavity, thereby displacing the lysis buffer from the cavity and partitioning each of the array of wells from adjacent wells, at the surface plane; and retaining intercellular material of the set of target cells, individually with the set of particles within the array of wells.Type: ApplicationFiled: March 17, 2020Publication date: October 22, 2020Inventors: Kalyan Handique, John Stark, Yadwinder Deol, Vishal Sharma
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Publication number: 20200128898Abstract: An adjustable hat has a first attachment member and a strap connection member that cooperate to allow a strap to be easily connected and removed from the adjustable hat. The two elements may also be reversed with regard to construction and attachment to parts of the hat. The two members can be disengaged from one another without having to access them in the space formed by the hat and the band.Type: ApplicationFiled: December 30, 2019Publication date: April 30, 2020Inventor: John Stark
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Patent number: 10633693Abstract: A system and method for target material capture, the method comprising: receiving a set of target cells into an array of wells defined at a surface plane of a substrate; receiving a set of particles into the array of wells, thereby co-capturing the set of target cells and the set of particles; achieving a desired state for the array of wells upon receiving a washing fluid into a cavity in communication with the array of wells; receiving a lysis buffer into the cavity; receiving a partitioning fluid into the cavity, thereby displacing the lysis buffer from the cavity and partitioning each of the array of wells from adjacent wells, at the surface plane; and retaining intercellular material of the set of target cells, individually with the set of particles within the array of wells.Type: GrantFiled: September 9, 2019Date of Patent: April 28, 2020Assignee: Celsee Diagnostics, Inc.Inventors: Kalyan Handique, John Stark, Yadwinder Deol, Vishal Sharma
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Patent number: 10517344Abstract: An adjustable hat has a first attachment member and a strap connection member that cooperate to allow a strap to be easily connected and removed from the adjustable hat. The two elements may also be reversed with regard to construction and attachment to parts of the hat. The two members can be disengaged from one another without having to access them in the space formed by the hat and the band.Type: GrantFiled: November 6, 2017Date of Patent: December 31, 2019Inventor: John Stark
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Publication number: 20190133231Abstract: An adjustable hat has a first attachment member and a strap connection member that cooperate to allow a strap to be easily connected and removed from the adjustable hat. The two elements may also be reversed with regard to construction and attachment to parts of the hat. The two members can be disengaged from one another without having to access them in the space formed by the hat and the band.Type: ApplicationFiled: November 6, 2017Publication date: May 9, 2019Inventor: John Stark
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Publication number: 20190060107Abstract: Aspects of the present disclosure relate to a convective blanket that includes an air permeable upper sheet having a periphery. The convective blanket includes a lower sheet bonded to the upper sheet with a peripheral seal proximate to the periphery of the upper sheet to form an interior space therein between the upper and lower sheets. The convective blanket includes a wing portion partially surrounded by a portion of the peripheral seal and a body portion. Additional aspects relate to a system including the convective blanket and a method that uses the convective blanket.Type: ApplicationFiled: August 23, 2018Publication date: February 28, 2019Inventors: Matthew Zabel, Michael Vostal, Poeuth Pann, Jared J. Balthazor, Melanie L. Collins, Philip G. Dion, Daniel P. Doran, Marc A. Egeland, Yvonne Lund, Glenn R. Maharaj, Andrew J. McGregor, John Stark
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Patent number: 9969158Abstract: An electrospray emitter (10) for emitting a liquid comprising a sheet (40) having a channel (65) opening to an aperture (55) on a flat emitter surface extending across the sheet (40). A charging electrode (80) coupleable to an electrical supply and arranged to apply an electrical charge to liquid passing into the channel (65). A control electrode (50) proximal to the channel (65) for controlling electrospray emission, that may be embedded in the sheet. A non-wetting or insulating layer (30) may be applied to the sheet.Type: GrantFiled: November 11, 2010Date of Patent: May 15, 2018Assignee: QUEEN MARY & WESTFIELD COLLEGEInventors: John Stark, Mark Richard Shepherd
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Patent number: 9968082Abstract: A method of perfusing an organ or tissue includes perfusing the organ or tissue with a perfusion apparatus; detecting a condition representing at least one of an attitude of the perfusion apparatus or at least one shock experienced by the perfusion apparatus; and altering perfusion based upon the detected condition and/or recording the detected condition.Type: GrantFiled: August 31, 2015Date of Patent: May 15, 2018Assignee: LIFELINE SCIENTIFIC, INC.Inventors: Christopher P. Steinman, John Stark, Joel C. Hagen, Aaron R. Ferber, Rodney H. Monson, Evan D. Shapiro
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Patent number: 9845883Abstract: A shaft seal assembly for establishing a liquid-tight seal between a steering knuckle and an axle shaft is provided. The shaft seal assembly includes an outer case and a first elastomeric member attached to one another. The elastomeric member has a castellated feature including a plurality of projections extending in a radially outward direction and separated from one another by a plurality of grooves. When the shaft seal assembly is installed in the steering knuckle, a cavity is presented between the steering knuckle and the first elastomeric member. Together, the grooves and cavity allow air to flow from a hub on one side of the seal assembly to a vacuum port in the steering knuckle. The cavity extends circumferentially around the seal assembly, and thus, air flow from the hub to the vacuum port is not dependent upon the orientation of the seal assembly relative to the steering knuckle.Type: GrantFiled: June 8, 2012Date of Patent: December 19, 2017Assignee: Federal-Mogul LLCInventors: Richard M. Larson, David C. Rupp, Reynaldo Fernandez, John Stark, Gerald A. Greca
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Patent number: 9565853Abstract: An apparatus for separating gas bubbles that may be entrained in perfusate flow prevents such bubbles from continuing downstream and entering an organ or tissue. The apparatus may include a chamber having a top wall, a bottom wall and side walls. The chamber may include an inlet configured to allow at least one of gas and liquid to enter the chamber, an air opening configured to allow at least gas to exit the chamber and a first liquid opening configured to allow at least liquid to exit the chamber. The apparatus may function as an accumulator that reduces or eliminates pulsatility of the liquid flow and pressure. The apparatus may include a minimum volume of gas, initially or through the accumulation of gas, such that flow and pressure fluctuations in the liquid are dampened or eliminated. The apparatus may include a sampling port in a wall of the chamber.Type: GrantFiled: July 10, 2012Date of Patent: February 14, 2017Assignee: LIFELINE SCIENTIFIC, INC.Inventors: Christopher P. Steinman, Jeffrey S. Louis, Rick W. Walker, Evan D. Shapiro, Aaron R. Ferber, Rodney H. Monson, John Stark, Ross Lockwood
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Patent number: 9482179Abstract: A multi-layer cylinder head gasket is provided. The cylinder head gasket includes a plurality of layers of material, each of the layers has a plurality of openings including at least one cylinder bore opening and at least one pushrod opening. Each of the layers has an edge which surrounds the at least one pushrod opening, and the pushrod openings of the layers are aligned axially with one another. An eyelet extends axially in each of the pushrod openings and covers the edges of the layers for protecting a pushrod extending through the respective pushrod opening. The eyelet is made of a material that is softer than the material of the plurality of layers.Type: GrantFiled: July 15, 2014Date of Patent: November 1, 2016Assignee: Federal-Mogul CorporationInventors: Nicholas Nelson, Wilford Dean Virgin, Steven Kueltzo, Richard Larson, John Stark
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Publication number: 20150366183Abstract: A method of perfusing an organ or tissue includes perfusing the organ or tissue with a perfusion apparatus; detecting a condition representing at least one of an attitude of the perfusion apparatus or at least one shock experienced by the perfusion apparatus; and altering perfusion based upon the detected condition and/or recording the detected condition.Type: ApplicationFiled: August 31, 2015Publication date: December 24, 2015Inventors: Christopher P. STEINMAN, John STARK, Joel C. HAGEN, Aaron R. FERBER, Rodney H. MONSON, Evan D. SHAPIRO