Patents by Inventor John Stephen Robinson

John Stephen Robinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,2-substituted cyclopentanes as orexin receptor antagonists
    Patent number: 10689373
    Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Grant
    Filed: June 1, 2018
    Date of Patent: June 23, 2020
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Charlotte Fieldhouse, Angela Glen, Stephanie Maine, Tatsuhiko Fujimoto, John Stephen Robinson
  • 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20180282309
    Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Application
    Filed: June 1, 2018
    Publication date: October 4, 2018
    Inventors: Charlotte Fieldhouse, Angela Glen, Stephanie Maine, Tatsuhiko Fujimoto, John Stephen Robinson
  • 1,2-substituted cyclopentanes as orexin receptor antagonists
    Patent number: 10011588
    Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, (I) wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: July 3, 2018
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Charlotte Fieldhouse, Angela Glen, Stephanie Maine, Tatsuhiko Fujimoto, John Stephen Robinson
  • Substituted cyclopentanes, tetrahydrofuranes and pyrrolidines as orexin receptor antagonists
    Patent number: 9790220
    Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, Formula (I) wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: October 17, 2017
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Charlotte Fieldhouse, Angela Glen, Tatsuhiko Fujimoto, John Stephen Robinson
  • SUBSTITUTED CYCLOPENTANES, TETRAHYDROFURANES AND PYRROLIDINES AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20170073340
    Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, Formula (I) wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Application
    Filed: February 19, 2015
    Publication date: March 16, 2017
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Charlotte Fieldhouse, Angela Glen, Tatsuhiko Fujimoto, John Stephen Robinson
  • 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS
    Publication number: 20170066744
    Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, (I) wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Application
    Filed: February 19, 2015
    Publication date: March 9, 2017
    Inventors: Charlotte Fieldhouse, Angela Glen, Stephanie Maine, Tatsuhiko Fujimoto, John Stephen Robinson
  • Cyclopentylbenzamide derivatives and their use for the treatment of psychotic and cognitive disorders
    Patent number: 9493432
    Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein n, L, X, Ra, Rb, R1, R2 and R3 their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: November 15, 2016
    Assignee: Takeda Pharmaceuticals Company Limited
    Inventors: Charlotte Fieldhouse, Angela Glen, John Stephen Robinson, Tatsuhiko Fujimoto
  • Cyclopentylbenzamide Derivatives and their Use for the Treatment of Psychotic and Cognitive Disorders
    Publication number: 20160222030
    Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein n, L, X, Ra, Rb, R1, R2 and R3 their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Application
    Filed: October 14, 2014
    Publication date: August 4, 2016
    Inventors: Charlotte Fieldhouse, Angela Glen, John Stephen Robinson, Tatsuhiko Fujimoto
  • Cycloalkyl and heterocycloalkyl compounds as orexin receptor antagonists
    Patent number: 9156829
    Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: October 13, 2015
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Charlotte Fieldhouse, Angela Glen, Stephanie Maine, Tatsuhiko Fujimoto, John Stephen Robinson
  • NOVEL COMPOUNDS
    Publication number: 20150232460
    Abstract: The present invention provides compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein L, X, Ra, Rb, R1, R2 and R3 are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
    Type: Application
    Filed: February 19, 2015
    Publication date: August 20, 2015
    Inventors: Charlotte Fieldhouse, Angela Glen, Stephanie Maine, Tatsuhiko Fujimoto, John Stephen Robinson
  • 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
    Patent number: 8026236
    Abstract: The present invention relates to 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives having the general Formula I to pharmaceutical compositions comprising the same as well as to the use of these derivatives for the preparation of a medicament for the treatment of cathepsin S related diseases such as atherosclerosis, obesity, inflammation and immune disorders, such as rheumatoid arthritis, psoriasis, cancer, and chronic pain, such as neuropathic pain.
    Type: Grant
    Filed: January 13, 2010
    Date of Patent: September 27, 2011
    Assignee: N.V. Organon
    Inventors: John Stephen Robinson, Philip Stephen Jones, Jiaqiang Cai, David Jonathan Bennett
  • 6-PHENYL-1H-IMIDAZO[4,5-c]PYRIDINE-4-CARBONITRILE DERIVATIVES
    Publication number: 20100184761
    Abstract: The present invention relates to 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives having the general Formula I to pharmaceutical compositions comprising the same as well as to the use of these derivatives for the preparation of a medicament for the treatment of cathepsin S related diseases such as atherosclerosis, obesity, inflammation and immune disorders, such as rheumatoid arthritis, psoriasis, cancer, and chronic pain, such as neuropathic pain.
    Type: Application
    Filed: January 13, 2010
    Publication date: July 22, 2010
    Inventors: John Stephen Robinson, Philip Stephen Jones, Jiaqiang Cai, David Jonathan Bennett
  • Process for flocculating suspensions
    Patent number: 7070696
    Abstract: A process of flocculating and dewatering an aqueous suspension of suspended solids comprising, introducing into the suspension, (a) substantially linear polymer, (b) structured polymer, characterised in that the polymers are introduced into the substrate sequentially. The process brings about improvements in filtration.
    Type: Grant
    Filed: March 22, 2002
    Date of Patent: July 4, 2006
    Assignee: Ciba Specialty Chemicals Water Treatments Ltd.
    Inventors: Steven Weir, Michael Green, John Stephen Robinson, Tony Whittaker, Malcolm Skinner
  • Process for flocculating suspensions
    Publication number: 20040124154
    Abstract: A process of flocculating and dewatering an aqueous suspension of suspended solids comprising, introducing into the suspension, (a) substantially linear polymer, (b) structured polymer, characterised in that the polymers are introduced into the substrate sequentially. The process brings about improvements in filtration.
    Type: Application
    Filed: January 29, 2004
    Publication date: July 1, 2004
    Inventors: Steven Weir, Michael Green, John Stephen Robinson, Tony Whittaker, Malcolm Skinner