Abstract: Medical devices and related methods are described. The medical device may include a handle having a proximal end that includes a seal. The seal may include a first portion and a second portion. The first portion may define a proximal opening configured to receive a shaft of a medical instrument, at least part of the first portion proximate the proximal opening being a flexible membrane. The second portion may be integral with or coupled to the first portion. The flexible membrane may be movable relative to the second portion to form and maintain a fluid-tight seal with the shaft.

Abstract: Medical devices and related systems and methods are described. The medical device may include a handle and a sheath extending from the handle, wherein the handle includes a hub. The hub may define a proximal opening and a chamber. The sheath may define a lumen in fluid communication with the proximal opening and the chamber. The hub may include at least one arm extending radially outward from the hub. An end of the at least one arm may be curved and may include a wheel or a concave support.

Abstract: Medical systems and devices configured to adjust fluid flow are described. The medical system may include a medical device having a handle coupled to a shaft that includes at least one working channel. The handle may include a port in communication with the at least one working channel and configured to connect to a source of fluid or vacuum. The medical system also may include a control mechanism coupled to or integrated into the handle. The control mechanism may include a grippable portion configured to adjust fluid flow through the at least one working channel of the medical device when a user squeezes the grippable portion or moves the grippable portion relative to the handle.

Abstract: Medical devices, systems, and related methods are described. The medical device may include a handle with a hub, a suction port, and a ventilation mechanism; and a sheath integral with or coupled to the handle. The hub may define a lumen and a proximal opening configured to receive a shaft of a medical instrument, and the suction port may be in fluid communication with the lumen and configured to be connected to a vacuum source. The ventilation mechanism may include a housing coupled to the hub and may be movable to cover and uncover at least one aperture of the hub or the suction port.

Abstract: Capture devices and related systems are described, including a medical device that includes a handle coupled to an end effector. The end effector may be formed from a first wire and a second wire each forming a coil. The coil of the first wire may be proximal to the coil of the second wire. The first wire and the second wire each include a shape memory material, such that the end effector includes a collapsed configuration when constrained within a sheath and an expanded configuration when unconstrained by the sheath. While in the expanded configuration, the first wire and the second wire may be movable relative to each other top provide a space, e.g., an opening, between the coil of the first wire and the coil of the second wire.

Abstract: Medical devices, systems, and related methods useful for removing objects from patient anatomy during a medical procedure are described. The medical device may include a sheath defining a lumen, and a retrieval device slidably disposed within the lumen. The retrieval device may include a shaft including an expandable frame and a cover coupled to the frame. The retrieval device may move between a collapsed configuration while the frame is within the sheath and an expanded configuration while the frame is outside the sheath. The retrieval device may be configured to receive a laser fiber therein, such that the laser fiber may be used to break apart objects while within the retrieval device to facilitate removal of objects from patient anatomy. The cover may be laser-resistant, porous, and configured to prevent passage of object particles therethrough.

Abstract: Medical devices and related methods are described, including a medical device that includes a shaft including a distal articulating portion; and a handle coupled to the shaft. The handle may include a first actuator moveably coupled to a handle body of the handle, and the first actuator may be configured to initiate bending of the distal articulating portion in a first direction when the first actuator is translated along a first axis transverse from a central longitudinal axis of the medical device.

Abstract: Medical devices and systems are described. The medical device may include a handle that includes a hub, a grip portion, and an arm. The hub may define a lumen having a proximal opening. The arm may extend proximally from the hub and may be coupled to a member slidable or rotatable relative to the arm. The grip portion may extend transverse to the lumen of the hub. The grip portion may be configured to receive a palm of a user's hand while a thumb of the user's hand controls sliding or rotation of the member.

Abstract: Medical devices and systems with articulating shafts are described. The medical device may include a handle including an articulation mechanism, e.g., with an actuator configured to receive user input, and a shaft extending distally from the handle. The shaft may define an accessory channel that houses a composite cable extending from a proximal end of the shaft to a distal portion of the shaft. The composite cable may include at least one electrical wire operable coupled to at least one electronic component at or proximate a distal end of the shaft. The articulation mechanism may be configured to articulate the distal portion of the shaft by controlling movement of the composite cable by the user input received by the actuator.

Abstract: A retrieval device attachable to a scope includes a handle which has an attachment portion configured to couple the handle to the scope; a shaft coupled to the handle having a wire immovably coupled to the handle; and a sheath movable relative to the handle over the wire between a distal position and a proximal position via an actuator of the handle. The actuator actuates a slider assembly of the handle. The slider assembly is coupled to the sheath and movable relative to the attachment portion to move the sheath and an expandable end effector coupled to the distal end of the wire. The end effector is movable between a collapsed configuration when the sheath is moved distally to the distal position to cover the end effector and an expanded configuration when the sheath is moved proximally to the proximal position, uncovering the end effector.

Abstract: A retrieval device attachable to a scope includes a handle which has an attachment portion configured to couple the handle to the scope; a shaft coupled to the handle having a wire immovably coupled to the handle; and a sheath movable relative to the handle over the wire between a distal position and a proximal position via an actuator of the handle. The actuator actuates a slider assembly of the handle. The slider assembly is coupled to the sheath and movable relative to the attachment portion to move the sheath and an expandable end effector coupled to the distal end of the wire. The end effector is movable between a collapsed configuration when the sheath is moved distally to the distal position to cover the end effector and an expanded configuration when the sheath is moved proximally to the proximal position, uncovering the end effector.

Abstract: Medical devices and related methods are described, including a medical device that includes a handle including a housing. The housing may include a grip and an actuator. The handle may further include an imaging module including a printed circuit board, and a laser module including a first laser source configured to couple to a first laser fiber and a second laser source configured to couple to a second laser fiber. The laser module and the imaging module may be contained within the housing or the imaging module, the laser module, or both the imaging module and the laser module may be selectively attachable to and detachable from the housing.

Abstract: Medical devices and related methods are discussed, including a medical device that includes a handle with a housing and an actuator mechanism disposed within the housing. The actuator mechanism may include a biasing member and a disk rotatable between a first position and a second position, e.g., the biasing member having a first length and exerting a first distal force on the disk in the first position, and having a second length different from the first length and exerting a second distal force on the disk less than the first distal force in the second position.

Abstract: A scope adapter system includes an adapter body coupled to a handle of a scope device, a rigid shaft, and a mounting mechanism removably coupled to the shaft. The shaft includes a shaft lumen which is sized and shaped to slidably receive a flexible elongated member of the device. A distal end of the lumen is sized so that, when a distal end of the member is received therein, the distal end of the member is snugly held so that an aim of the shaft aims the distal end of the member. The mechanism mounts a proximal end of the shaft to the body so that, when the body is coupled to the handle, the mechanism is mounted on the body and coupled to the shaft and the member is inserted into the lumen so that movement of the handle effects corresponding movements of the distal end of the member.

Abstract: A medical accessory mounting system may include a medical device having a handle and an elongate shaft extending distally from the handle. The handle may include at least one connecting structure formed in an outer surface of the handle, the at least one connecting structure comprising a plurality of ridges. The at least one connecting structure may be configured to engage with an accessory connecting structure formed on an outer surface of an accessory device.

Abstract: A retrieval device attachable to a scope includes a handle which has an attachment portion configured to couple the handle to the scope; a shaft coupled to the handle having a wire immovably coupled to the handle; and a sheath movable relative to the handle over the wire between a distal position and a proximal position via an actuator of the handle. The actuator actuates a slider assembly of the handle. The slider assembly is coupled to the sheath and movable relative to the attachment portion to move the sheath and an expandable end effector coupled to the distal end of the wire. The end effector is movable between a collapsed configuration when the sheath is moved distally to the distal position to cover the end effector and an expanded configuration when the sheath is moved proximally to the proximal position, uncovering the end effector.

Abstract: A retrieval device attachable to a scope includes a handle which has an attachment portion configured to couple the handle to the scope; a shaft coupled to the handle having a wire immovably coupled to the handle; and a sheath movable relative to the handle over the wire between a distal position and a proximal position via an actuator of the handle. The actuator actuates a slider assembly of the handle. The slider assembly is coupled to the sheath and movable relative to the attachment portion to move the sheath and an expandable end effector coupled to the distal end of the wire. The end effector is movable between a collapsed configuration when the sheath is moved distally to the distal position to cover the end effector and an expanded configuration when the sheath is moved proximally to the proximal position, uncovering the end effector.

Abstract: Systems and methods for treating a patient may include accessing an anatomical structure with a single use visualization device, using the imaging capabilities of the single use visualization device within the anatomical structure, and in some cases, advancing the single use visualization device beyond the anatomical structure to and toward another anatomical structure within the patient. Disposable elements may be used with or added to the single use visualization device to accomplish tasks normally performed with reusable devices.

Abstract: A medical accessory mounting system may include a medical device having a handle and an elongate shaft extending distally from the handle. The handle may include at least one connecting structure formed in an outer surface of the handle, the at least one connecting structure comprising a plurality of ridges. The at least one connecting structure may be configured to engage with an accessory connecting structure formed on an outer surface of an accessory device.

Abstract: A retrieval device attachable to a scope includes a handle which has an attachment portion configured to couple the handle to the scope; a shaft coupled to the handle having a wire immovably coupled to the handle; and a sheath movable relative to the handle over the wire between a distal position and a proximal position via an actuator of the handle. The actuator actuates a slider assembly of the handle. The slider assembly is coupled to the sheath and movable relative to the attachment portion to move the sheath and an expandable end effector coupled to the distal end of the wire. The end effector is movable between a collapsed configuration when the sheath is moved distally to the distal position to cover the end effector and an expanded configuration when the sheath is moved proximally to the proximal position, uncovering the end effector.