Patents by Inventor John Surtees

John Surtees has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of 2-oxo-1-pyrrolidine derivatives
    Patent number: 8338621
    Abstract: The present invention relates to alternative processes for the preparation of 2-oxo-1-pyrrolidine derivatives of formula (I) Particularly, the present invention relates to alternative processes for the synthesis of levetiracetam, brivaracetam and seletracetam.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: December 25, 2012
    Assignee: UCB S.A.
    Inventors: John Surtees, Didier Bouvy, Antoine Thomas, Yves Combret, Michael Frank, Gunther Schmidt, Guy Duchene
  • Process for preparing 2-oxo-1-pyrrolidine derivatives
    Patent number: 7629474
    Abstract: The present invention relates to a new process for preparing 2-oxo-I-pyrrolidine derivatives of general formula (I) wherein the substituents are as defined in the specification.
    Type: Grant
    Filed: September 13, 2004
    Date of Patent: December 8, 2009
    Assignee: UCB Pharma S.A.
    Inventors: John Surtees, Françoise Lurquin, Ousmane Diouf
  • Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of Levetiracetam and analogues
    Patent number: 7563912
    Abstract: The present invention relates to an improved process for the preparation of (S)-(?)-?-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein R1 is methyl or ethyl; and R2 is C?2#191 -C?4#191 alkyl, C?2#191-C?4#191 alkenyl or C?2#191-C?4#191 alkynyl, optionally substituted by one or more halogen, and their preparation processes.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: July 21, 2009
    Assignee: UCB Pharma, S.A.
    Inventors: Celal Ates, John Surtees, Anne-Catherine Burteau, Violeta Marmon, Emile Cavoy
  • Chemical compounds with dual activity, processes for their preparation and pharmaceutical compositions
    Patent number: 7544675
    Abstract: The present invention concerns chemical compounds combining affinity and antagonism against the human m3 muscarinic receptor with activity as selective phosphodiesterase IV (PDE IV) inhibitors, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Grant
    Filed: March 29, 2003
    Date of Patent: June 9, 2009
    Assignee: UCB, S.A.
    Inventors: Laurent Provins, Berend Jan Van Keulen, John Surtees, Patrice Talaga, Bernard Christophe
  • Hydrogenation catalysts
    Patent number: 7504353
    Abstract: A catalyst comprising a chiral transition metal-(1,2-bis(2,5-dialkylphospholano) complex immobilized on a specific zeolitic support useful for the hydrogenation of prochiral substrates.
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: March 17, 2009
    Assignee: UCB Pharma, S.A.
    Inventors: Pierre Jacobs, François Collignon, Emmanuel Van Vaerenbergh, John Surtees, Anne-Catherine Burteau
  • Process for the preparation of 2- (2- (4- (bis (4-flourophenyl) methyl) -pipe razin-1-yl) ethoxy acetic acid derivatives or corresponding salt forms thereof and intermediates therefor
    Publication number: 20080177071
    Abstract: The present invention relates to a process for the manufacture of 2-{2-[4-(bis(4-fluorophenyl)methyl)-1-piperazinyl]ethoxy}acetic acids, amides or related derivatives, of the general formula (I) wherein: Y represents hydroxy or —NR1R2; R1 and R2 each independently represent hydrogen or C?1-4#191 alkyl; m is 1 or 2, and n is 1 or 2, as well as the non-toxic, pharmaceutically acceptable salts and mixtures thereof. The present invention concerns also a polymorphic form of efletirizine.
    Type: Application
    Filed: October 29, 2007
    Publication date: July 24, 2008
    Inventors: Ousmane Diouf, John Surtees
  • PROCESS FOR THE PREPARATION OF 2-OXO-1-PYRROLIDINE DERIVATIVES
    Publication number: 20080009638
    Abstract: The present invention relates to alternative processes for the preparation of 2-oxo-1-pyrrolidine derivatives of formula (I) Particularly, the present invention relates to alternative processes for the synthesis of levetiracetam, brivaracetam and seletracetam.
    Type: Application
    Filed: December 19, 2006
    Publication date: January 10, 2008
    Applicant: UCB S.A.
    Inventors: John Surtees, Didier Bouvy, Antoine Thomas, Yves Combert, Michael Frank, Gunther Schmidt, Guy Duchene
  • Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues
    Publication number: 20070142647
    Abstract: The present invention relates to an improved process for the preparation of (S)-(-)-?-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein R1 is methyl or ethyl; and R2 is C2-C4 alkyl, C2-C4 alkenyl or C2-C4 alkynyl, optionally substituted by one or more halogen, and their preparation processes.
    Type: Application
    Filed: October 2, 2006
    Publication date: June 21, 2007
    Inventors: Celal Ates, John Surtees, Anne-Catherine Burteau, Violeta Marmon, Emile Cavoy
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Patent number: 7217826
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing ?-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-?-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Grant
    Filed: January 4, 2005
    Date of Patent: May 15, 2007
    Assignee: UCB Farchim S.A.
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • Process for preparing 2-oxo-1-pyrrolidine derivatives
    Publication number: 20070100150
    Abstract: The present invention relates to a new process for preparing 2-oxo-1-pyrrolidine derivatives of general formula (I) wherein the substituents are as defined in the specification.
    Type: Application
    Filed: September 13, 2004
    Publication date: May 3, 2007
    Applicant: UCB, S.A.
    Inventors: John Surtees, Francoise Lurquin, Ousmane Diouf
  • Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of Levetiracetam and analogues
    Publication number: 20060258734
    Abstract: The present invention relates to an improved process for the preparation of (S)-(?)-?-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein R1 is methyl or ethyl; and R2 is C?2#191 -C?4#191 alkyl, C?2#191-C?4#191 alkenyl or C?2#191-C?4#191 alkynyl, optionally substituted by one or more halogen, and their preparation processes.
    Type: Application
    Filed: July 18, 2006
    Publication date: November 16, 2006
    Inventors: Celal Ates, John Surtees, Anne-Catherine Burteau, Violeta Marmon, Emile Cavoy
  • Oxopyrrolidine compounds, preparation of said compounds and their use in the manufacturing of levetiracetam and analogues
    Patent number: 7122682
    Abstract: The present invention relates to an improved process for the preparation of (S)-(?)-?-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: October 17, 2006
    Assignee: UCB, S.A.
    Inventors: Celal Ates, John Surtees, Anne-Catherine Burteau, Violeta Marmon, Emile Cavoy
  • Hydrogenation catalysts
    Publication number: 20060224001
    Abstract: A catalyst comprising a chiral transition metal-(1,2-bis(2,5-dialkylphospholano) complex immobilised on a specific zeolitic support useful for the hydrogenation of prochiral substrates.
    Type: Application
    Filed: January 9, 2004
    Publication date: October 5, 2006
    Applicant: UCB, S.A.
    Inventors: Pierre Jacobs, Francois Collignon, Emmanuel Van Vaerenbergh, John Surtees, Anne-Catherine Burteau
  • Chemical compounds with dual activity, processes for their preparation and pharmaceutical compositions
    Publication number: 20060074068
    Abstract: The present invention concerns chemical compounds combining affinity and antagonism against the human m3 muscarinic receptor with activity as selective phosphodiesterase IV (PDE IV) inhibitors, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
    Type: Application
    Filed: March 29, 2003
    Publication date: April 6, 2006
    Applicant: UCB, S.A.
    Inventors: Laurent Provins, Berend Van Keulen, John Surtees, Patrice Talaga, Bernard Christophe
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Patent number: 6969770
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing ?-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-?-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: November 29, 2005
    Assignee: U.C.B. Farchim S.A.
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Publication number: 20050159475
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing ?-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-?-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Application
    Filed: January 4, 2005
    Publication date: July 21, 2005
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Patent number: 6858740
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing ?-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-?-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Grant
    Filed: July 1, 2003
    Date of Patent: February 22, 2005
    Assignee: UCB Farchim S.A.
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann
  • Process for the preparation of 2-(2-(4-(bis(4-fluorophenyl)methyl)-piperazin-1-yl)ethoxy)acetic acid derivatives or corresponding salt forms thereof and intermediates therefor
    Publication number: 20040254375
    Abstract: The present invention relates to a process for the manufacture of 2-{2-[4-(bis(4-fluorophenyl)methyl)-1-piperazinyl]ethoxy}acetic acids, amides or related derivatives, of the general formula (I) wherein: Y represents hydroxy or —NR1R2; R1 and R2 each independently represent hydrogen or C?1-4#191 alkyl; m is 1 or 2, and n is 1 or 2, as well as the non-toxic, pharmaceutically acceptable salts and mixtures thereof. The present invention concerns also a polymorphic form of efletirizine.
    Type: Application
    Filed: January 26, 2004
    Publication date: December 16, 2004
    Inventors: Ousmane Diouf, John Surtees
  • Oxopyrrolidine compounds, preparations of said compounds and their use in the manufacturing of levetiracetam and analogues
    Publication number: 20040204476
    Abstract: The present invention relates to an improved process for the preparation of (S)-(−)-&agr;-ethyl-2-oxo-1-pyrrolidine acetamide and analogues thereof. The invention also relates to compounds of the general formula (6) wherein R1 is methyl or ethyl; and R2 is C?2#19 1-C?4#191 alkyl, C?2#191 -C?4#191 alkenyl or C?2#191-C?4#191 alkynyl, optionally substituted by one or more halogen, and their preparation processes.
    Type: Application
    Filed: February 10, 2004
    Publication date: October 14, 2004
    Inventors: Celal Ates, John Surtees, Anne-Catherine Burteau, Violeta Marmon, Emile Cavoy
  • 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
    Publication number: 20040192757
    Abstract: The invention concerns 2-oxo-1-pyrrolidine derivatives and a process for preparing them and their uses. The invention also concerns a process for preparing &agr;-ethyl-2-oxo-1-pyrrolidine acetamide derivatives from unsaturated 2-oxo-1-pyrrolidine derivatives. Particularly the invention concerns novel intermediates and their use in methods for the preparation of S-&agr;-ethyl-2-oxo-1-pyrrolidine acetamide.
    Type: Application
    Filed: April 15, 2004
    Publication date: September 30, 2004
    Inventors: John Surtees, Violeta Marmon, Edmond Differding, Vincent Zimmermann