Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: A method is disclosed for additively manufacturing a composite structure. The method may include directing a continuous reinforcement into a print head, and coating the continuous reinforcement with a first matrix component inside of the print head. The method may further include coating the continuous reinforcement with a second matrix component, discharging the continuous reinforcement through a nozzle of the print head, and moving the print head in multiple dimensions during the discharging. The first and second matrix components interact to cause hardening of a matrix around the continuous reinforcement.

Abstract: A method is disclosed for additively manufacturing a composite structure. The method may include directing a continuous reinforcement into a print head, and coating the continuous reinforcement with a first matrix component inside of the print head. The method may further include coating the continuous reinforcement with a second matrix component, discharging the continuous reinforcement through a nozzle of the print head, and moving the print head in multiple dimensions during the discharging. The first and second matrix components interact to cause hardening of a matrix around the continuous reinforcement.

Abstract: A system is disclosed for use in fabricating a custom vehicle. The system may include an additive manufacturing machine, and at least one computing device operatively connected to the additive manufacturing machine. The at least one computing device includes a memory having computer-executable instructions stored thereon and a processor configured to execute the computer-executable instructions to receive from a user a selection of available components that can be built into the custom vehicle, and to generate a unique model of the custom vehicle based on the selection. The processor is further configured to execute the computer-executable instructions to generate code associated with the unique model, and to direct the code to the additive manufacturing machine, causing the additive manufacturing machine to additively manufacture at least a portion of the custom vehicle.

Abstract: A method is disclosed for additively manufacturing a composite structure. The method may include directing a continuous reinforcement into a print head, and coating the continuous reinforcement with a first matrix component inside of the print head. The method may further include coating the continuous reinforcement with a second matrix component, discharging the continuous reinforcement through a nozzle of the print head, and moving the print head in multiple dimensions during the discharging. The first and second matrix components interact to cause hardening of a matrix around the continuous reinforcement.

Abstract: A method is disclosed for additively manufacturing a composite structure. The method may include directing a continuous reinforcement into a print head, and coating the continuous reinforcement with a first matrix component inside of the print head. The method may further include coating the continuous reinforcement with a second matrix component, discharging the continuous reinforcement through a nozzle of the print head, and moving the print head in multiple dimensions during the discharging. The first and second matrix components interact to cause hardening of a matrix around the continuous reinforcement.

Abstract: A method is disclosed for additively manufacturing a composite structure. The method may include directing a continuous reinforcement into a print head, and coating the continuous reinforcement with a first matrix component inside of the print head. The method may further include coating the continuous reinforcement with a second matrix component, discharging the continuous reinforcement through a nozzle of the print head, and moving the print head in multiple dimensions during the discharging. The first and second matrix components interact to cause hardening of a matrix around the continuous reinforcement.

Abstract: A misting device with quick release interchangeable cartridge is disclosed for atomizing and discharging a composition as a mist for topical application of the composition to the body or diffusing the composition into the ambient air. The cartridge quickly loads and unloads into an interior chamber of the container through a quick release coupling mechanism. The coupling mechanism may create a friction fit engagement. An atomizer atomizes the composition. A base maintains the container in an upright position for formulation of the composition in the cavity of the cartridge.

Abstract: A misting device with quick release interchangeable cartridge is disclosed for atomizing and discharging a composition as a mist for topical application of the composition to the body or diffusing the composition into the ambient air. The cartridge comprises an atomizer and quickly attaches and detaches from a body using a coupling mechanism which may create a friction fit engagement. The atomizer atomizes the composition. A base maintains the body in an upright position for formulation of the composition in the cavity of the cartridge.

Abstract: An electrical contact material which consists of a mixture of silver, 5 to 50 weight per cent of copper and 2 to 20 weight per cent of lanthanum, strontium chromite of formula La.sub.1-x Sr.sub.x CrO.sub.3, where the values of x lie between 0 and 1.0, formed as a hard, chemically inert, non-metallic phase of high electrical conductivity both within the bulk of, and at the surface of, the contact material. Methods of producing the electrical contact materials utilizing powder metallurgical techniques are outlined.

Abstract: The material consists of a mixture of silver and 1.0 to 20 weight per cent of lanthanum, strontium chromite of the formula La.sub.1.sub.-x Sr.sub.x CrO.sub.3, where the values of x lie between 0 and 1.0. The addition of 2.5 to 20 weight per cent of cadmium oxide further improves the electrical contact material by providing anti-weld properties to the contact interface. The electrical contacts are formed from the contact material by powder metallurgy techniques.