Abstract: An integrated lancet/biosensor comprised of a small, sharply tapered silicon lance and a body region containing active devices, passive trimming structures and features for accurate assembly. The lancet contains a series of electrodes covered with a specialized reagent to provide an output signal proportional to the quantity of the specific material in the blood or other bodily fluid. Trimming and amplification of the electrical signal are achieved with front-end electronic circuitry fabricated on the lancet body. The lancet is manufactured using integrated circuit fabrication techniques and micromachining techniques, and assembled into a disposable probe tip that contains a lead frame and pins. The probe tip may be attached to a pencil-shaped meter body that has additional circuitry for references, compensation, display drivers and external communication. Various embodiments are disclosed.