Patents by Inventor John T. Heap

John T. Heap has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA molecules and methods
    Patent number: 10544422
    Abstract: The present application discloses a DNA molecule comprising a modified Group II intron which does not express the intron-encoded reverse transcriptase but which contains a modified selectable marker gene in the reverse orientation, wherein the marker gene comprises a Group I intron in forward orientation of causing expression in a bacteria cell of the class Clostridia and wherein the DNA molecule comprises sequences that allow for the insertion of the RNA transcript of the Group II intron in the chromosome of a bacterial cell of the class Clostridia. A method of introducing a nucleic acid molecule into a site of a DNA molecule in a bacterial cell of the class Clostridia is also provided. The DNA molecule and the method are useful for making mutations Clostridium spp.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: January 28, 2020
    Assignee: Morvus Technology Limited
    Inventors: Nigel P. Minton, John T. Heap
  • DNA MOLECULES AND METHODS
    Publication number: 20160160222
    Abstract: The present application discloses a DNA molecule comprising a modified Group II intron which does not express the intron-encoded reverse transcriptase but which contains a modified selectable marker gene in the reverse orientation, wherein the marker gene comprises a Group I intron in forward orientation of causing expression in a bacteria cell of the class Clostridia and wherein the DNA molecule comprises sequences that allow for the insertion of the RNA transcript of the Group II intron in the chromosome of a bacterial cell of the class Clostridia. A method of introducing a nucleic acid molecule into a site of a DNA molecule in a bacterial cell of the class Clostridia is also provided. The DNA molecule and the method are useful for making mutations Clostridium spp.
    Type: Application
    Filed: December 4, 2015
    Publication date: June 9, 2016
    Inventors: NIGEL P. MINTON, JOHN T. HEAP
  • DNA MOLECULES AND METHODS
    Publication number: 20110124109
    Abstract: The present application discloses a DNA molecule comprising a modified Group II intron which does not express the intron-encoded reverse transcriptase but which contains a modified selectable marker gene in the reverse orientation, wherein the marker gene comprises a Group I intron in forward orientation of causing expression in a bacteria cell of the class Clostridia and wherein the DNA molecule comprises sequences that allow for the insertion of the RNA transcript of the Group II intron in the chromosome of a bacterial cell of the class Clostridia. A method of introducing a nucleic acid molecule into a site of a DNA molecule in a bacterial cell of the class Clostridia is also provided. The DNA molecule and the method are useful for making mutations Clostridium app.
    Type: Application
    Filed: June 21, 2007
    Publication date: May 26, 2011
    Inventors: Nigel P. Minton, John T. Heap