Patents by Inventor John T. Tossberg

John T. Tossberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF SYNTHESIZING MRNA AND FUNCTIONAL PROTEINS FROM SYNTHETIC DOUBLE STRANDED DNA
    Publication number: 20230002799
    Abstract: Disclosed are methods for preparing mRNA and proteins from synthetic DNA.
    Type: Application
    Filed: December 11, 2020
    Publication date: January 5, 2023
    Inventors: John T. Tossberg, Thomas M. Aune
  • Characterizing Gastro-Intestinal Disease
    Publication number: 20180171408
    Abstract: A method for characterizing a gastro-intestinal disease in a subject involves comparing ratios of expression levels of genes in a biological sample from a subject to references, wherein the gastro-intestinal disease is characterized based on a difference in the ratios of the expression values of genes in the biological sample from the subject as compared to the references.
    Type: Application
    Filed: December 7, 2017
    Publication date: June 21, 2018
    Inventors: Thomas M. Aune, Philip S. Crooke, Nancy J. Olsen, John T. Tossberg
  • CHARACTERIZING MULTIPLE SCLEROSIS
    Publication number: 20140329242
    Abstract: A method for characterizing multiple sclerosis in a subject involves comparing ratios of expression levels of genes in a biological sample from a subject to references, wherein the multiple sclerosis is characterized based on a difference in the ratios of the expression values of genes in the biological sample from the subject as compared to the references.
    Type: Application
    Filed: September 12, 2012
    Publication date: November 6, 2014
    Inventors: Thomas M. Aune, Philip S. Crooke, Nancy J. Olsen, John T. Tossberg
  • Characterizing Gastro-Intestinal Disease
    Publication number: 20140148357
    Abstract: A method for characterizing a gastro-intestinal disease in a subject involves comparing ratios of expression levels of genes in a biological sample from a subject to references, wherein the gastro-intestinal disease is characterized based on a difference in the ratios of the expression values of genes in the biological sample from the subject as compared to the references.
    Type: Application
    Filed: November 25, 2013
    Publication date: May 29, 2014
    Applicant: Vanderbilt University
    Inventors: Thomas M. Aune, Philip S. Crooke, Nancy J. Olsen, John T. Tossberg
  • Promoter of a maize major latex protein gene and methods of using it to express heterologous nucleic acids in transformed plants
    Patent number: 6861577
    Abstract: Compositions and methods to aid in protecting plants from invading pathogenic organisms are provided. The compositions of the invention comprise an anti-pathogenic gene, including the promoter driving expression of the gene, and the protein encoded by the anti-pathogenic gene. The compositions find use in methods for reducing or eliminating damage to plants caused by plant pathogens. Transformed plants, plant cells, tissues, and seed are also provided having enhanced disease resistance.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: March 1, 2005
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Pedro A. Navarro Acevedo, Carl R. Simmons, John T. Tossberg, Nasser Yalpani
  • Methods for enhancing disease resistance in plants
    Patent number: 6586657
    Abstract: Compositions and methods for enhancing disease resistance in plants are provided. The method involves transforming a plant with an avirulence gene or alternatively with an avirulence gene and the complementing resistance gene. A pathogen inducible promoter or alternatively a weak constitutive promoter is used to control the desired level of disease control in the plant. Transformed plants, plant cells, tissues, and seed are also provided having enhanced disease resistance.
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: July 1, 2003
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Steven Briggs, Carl R. Simmons, John T. Tossberg
  • Maize NPR1 polynucleotides and methods of use
    Patent number: 6504084
    Abstract: The invention provides isolated NPR1 nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering NPR1 concentration and/or composition of plants. The invention further provides recombinant expression cassettes, host cells, and transgenic plants. Additionally, the present invention provides promoter elements capable of initiating constitutive expression in a plant. Further, the present invention provides for methods for screening putative activators of a plant resistance pathway.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: January 7, 2003
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Edmund H. Crane, III, Douglas A. Rice, Carl R. Simmons, John T. Tossberg, Gary A. Sandahl, Lingyu Zhang
  • Methods for enhancing disease resistance in plants
    Patent number: 6476292
    Abstract: Compositions and methods for enhancing disease resistance in plants are provided. The method involves transforming a plant with an avirulence gene or alternatively with an avirulence gene and the complementing resistance gene. A pathogen inducible promoter or alternatively a weak constitutive promoter is used to control the desired level of disease control in the plant. Transformed plants, plant cells, tissues, and seed are also provided having enhanced disease resistance.
    Type: Grant
    Filed: February 24, 1999
    Date of Patent: November 5, 2002
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Steven Briggs, Carl R. Simmons, John T. Tossberg
  • Major latex protein gene and promoter and their uses
    Publication number: 20020083493
    Abstract: Compositions and methods to aid in protecting plants from invading pathogenic organisms are provided. The compositions of the invention comprise an anti-pathogenic gene, including the promoter driving expression of the gene, and the protein encoded by the anti-pathogenic gene. The compositions find use in methods for reducing or eliminating damage to plants caused by plant pathogens. Transformed plants, plant cells, tissues, and seed are also provided having enhanced disease resistance.
    Type: Application
    Filed: August 31, 2001
    Publication date: June 27, 2002
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Pedro A. Navarro Acevedo, Carl R. Simmons, John T. Tossberg, Nasser Yalpani
  • Methods for enhancing disease resistance in plants
    Publication number: 20020029392
    Abstract: Compositions and methods for enhancing disease resistance in plants are provided. The method involves transforming a plant with an avirulence gene or alternatively with an avirulence gene and the complementing resistance gene. A pathogen inducible promoter or alternatively a weak constitutive promoter is used to control the desired level of disease control in the plant.
    Type: Application
    Filed: July 26, 2001
    Publication date: March 7, 2002
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Steven Briggs, Carl R. Simmons, John T. Tossberg