Patents by Inventor John T. Wilson

John T. Wilson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200370052
    Abstract: Provided herein are a selective pattern recognition receptor (PRR) agonist and a method of selectively activating a PRR. The selective PRR agonist includes a nucleic acid agonist and a macromolecule conjugated to the nucleic acid agonist. The method includes administering the selective PRR agonist to a subject, and cleaving at least a portion of the macromolecule conjugated to the nucleic acid agonist, the cleaving of at least a portion of the macromolecule permitting the agonist to bind a PRR.
    Type: Application
    Filed: January 9, 2019
    Publication date: November 26, 2020
    Inventors: John T. Wilson, Christian Palmer
  • Patent number: 10696985
    Abstract: A diblock copolymer, polymer vesicle, and method of forming a polymer vesicle are provided. The diblock polymer includes a hydrophilic first block and a second block including amine containing monomers and hydrophobic monomers. The polymer vesicle includes a diblock copolymer with a hydrophilic first block and a second block including amine containing monomers and hydrophobic monomers, and at least one active agent loaded in the polymer vesicle. The second block forms an inner hydrophobic domain of a vesicle membrane and the hydrophilic block forms a corona facing the exterior and aqueous interior of the vesicle membrane, the corona providing an outer shell that stabilizes the vesicle in aqueous media.
    Type: Grant
    Filed: June 6, 2017
    Date of Patent: June 30, 2020
    Assignee: Vanderbilt University
    Inventors: John T. Wilson, Daniel Shae
  • Patent number: 10648306
    Abstract: The system delivers liquid CO2 125 into the casing screened interval of an eductor pipe 110 within a water well. The eductor pipe 110 assembly extends from the top of the well (or land surface) to the top of a disk interval isolation assembly 123. The disk assembly isolates a predetermined length of screened interval, so liquid CO2 125 can be injected and contained within the interval and immediately outside the casing.
    Type: Grant
    Filed: May 21, 2019
    Date of Patent: May 12, 2020
    Assignee: ARIZONA CO2 SOLUTIONS LLC
    Inventors: Matthew Wallace, John T. Wilson
  • Publication number: 20200011163
    Abstract: The system delivers liquid CO2 125 into the casing screened interval of an eductor pipe 110 within a water well. The eductor pipe 110 assembly extends from the top of the well (or land surface) to the top of a disk interval isolation assembly 123. The disk assembly isolates a predetermined length of screened interval, so liquid CO2 125 can be injected and contained within the interval and immediately outside the casing.
    Type: Application
    Filed: May 21, 2019
    Publication date: January 9, 2020
    Applicant: ARIZONA CO2 SOLUTIONS LLC
    Inventors: Matthew Wallace, John T. Wilson
  • Publication number: 20170058437
    Abstract: In one aspect, parachute buffer materials are described herein. In some embodiments, parachute buffer materials described herein comprise a fabric formed from a plurality of fibers and a coating disposed on at least one outer surface of the fabric. The fibers have an inner component formed from a thermoplastic material and an outer component formed from a non-thermoplastic material. In some cases, the fabric is a woven fabric. Additionally, the coating can comprise or contain a silicone along with, or without, other functional components. Moreover, materials described herein can be used to form various structures for parachute buffering applications, and the coatings of materials described herein can enhance the materials' buffering performance.
    Type: Application
    Filed: June 10, 2016
    Publication date: March 2, 2017
    Inventors: Thomas W. THEYSON, Roger J. Crossfield, John T. Wilson
  • Publication number: 20110147069
    Abstract: The present invention provides a printed circuit board assembly that includes a first printed circuit board portion having a first thickness and including at least one plated through hole selectively electrically interconnecting electrically conductive layers of the printed circuit board assembly. A second printed circuit board portion is also provided that has a second thickness which is less than the first thickness and further includes another a second plated through hole array exposed on a surface of the second printed circuit board portion.
    Type: Application
    Filed: December 18, 2009
    Publication date: June 23, 2011
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Richard A. Quackenbush, James Su, John T. Wilson
  • Patent number: 7443217
    Abstract: A circuit for balancing delays through true and complement phases of complementary drivers includes: a first driver; a second driver; a first delay device coupled to an input of the first driver and having an input coupled to an input signal node; a second delay device coupled to an input of the second driver and having an input coupled to the input signal node through a first inverter, wherein the first and second delay devices are clocked such that an input signal reaches the first driver simultaneously with an inverted input signal reaching the second driver.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: October 28, 2008
    Assignee: Texas Instruments Incorporated
    Inventor: John T. Wilson
  • Patent number: 6634410
    Abstract: A mold apparatus and method for creating designs on the interior of molds includes a resilient form with an exterior and an interior, with a design formed on the exterior. A rigid support member is removably attached to the interior of the resilient form. A mold pattern, conformed to removably receive the rigid support member and the resilient form in combination, completes the basic elements of the invention. In one aspect of the invention, a passageway in the rigid support member is provided for introducing a gas between the rigid support member and the resilient form. In another aspect of the invention, a vacuum application device is provided for applying a vacuum to the interior of the resilient form.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: October 21, 2003
    Inventors: John H. Wilson, Robert E. Wilson, John T. Wilson
  • Patent number: 6548259
    Abstract: The invention relates to a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with a predetermined chromosome or nucleic acid molecule, and to the use of such molecules, alone or in concert with nucleic acid amplification methods.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: April 15, 2003
    Assignee: Yale University
    Inventors: David C. Ward, Michael Speicher, Stephen Gwyn Ballard, John T. Wilson
  • Publication number: 20030027159
    Abstract: The invention relates to a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with a predetermined chromosome or nucleic acid molecule, and to the use of such molecules, alone or in concert with nucleic acid amplification methods.
    Type: Application
    Filed: November 20, 2001
    Publication date: February 6, 2003
    Inventors: David C. Ward, Michael Speicher, Stephen Gwyn Ballard, John T. Wilson
  • Patent number: 6007994
    Abstract: The invention relates to a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with a predetermined chromosome or nucleic acid molecule, and to the use of such molecules, alone or in concert with nucleic acid amplification methods.
    Type: Grant
    Filed: June 2, 1998
    Date of Patent: December 28, 1999
    Assignee: Yale University
    Inventors: David C. Ward, Michael Speicher, Stephen Gwyn Ballard, John T. Wilson
  • Patent number: 5975639
    Abstract: An adjustable armrest assembly for an ergonomic chair provides for adjustment of the armrests in the forward and rearward direction relative to the front of the chair without inhibiting adjustment of the armrests in other directions. A support frame having one or more rails or rods running perpendicular to the chair front is connected to the seat bottom. The support frame is slidably mounted on the seat bottom to permit sideways adjustment of the width between the chair arms. A support base, to which the chair arm is connected, is slidably supported on the rods. A controller attached to the support frame moves the support base along a line extending from the front to the back of the chair. In one embodiment, the controller includes a gear assembly and a screw drive attached to a manual crank. An expandable linkage is provided between the left and right support member so that both are simultaneously moved while still permitting width adjustment.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: November 2, 1999
    Inventors: John T. Wilson, Milan Nechanicky
  • Patent number: 5599053
    Abstract: An improved sport and utility rack bracket particularly for use with pickup trucks. The bracket is a cantilevered assembly mounted on a side rail defining a portion of the cargo area of a pickup truck. The bracket has a rack attached thereto. The free end of the bracket, i.e., the cantilevered portion of the bracket, is parallel to or at some angle to the horizontal plane of the truck bed, transverse to the longitudinal axis of the vehicle.
    Type: Grant
    Filed: October 31, 1994
    Date of Patent: February 4, 1997
    Inventor: John T. Wilson
  • Patent number: 5289799
    Abstract: Disclosed is an automatic pet relief station (10) consisting of a housing (12) with an opening (14) to permit entry and exit of pets, an endless belt (16) positioned within the housing (12) to support a pet, a dispenser (18) positioned within the housing (12) for distributing litter on the endless belt (16), and a recycler (20) to cleanse soiled litter, dry the cleansed litter, and deposit the cleansed litter in the dispenser (18) for reuse.After a pet uses the relief station (10), the endless belt begins to travel, with soiled litter being received by the recycler (20) from one end of the endless belt (16), while clean litter is evenly distributed upon the opposite end of the endless belt (16) by the dispenser (18) as the endless belt (16) moves beneath the dispenser (18), thereby replacing the soiled litter. The recycler (20) cleanses the soiled litter, dries the cleansed litter, and deposits the dry cleansed litter into the dispenser (18) for reuse.
    Type: Grant
    Filed: November 25, 1992
    Date of Patent: March 1, 1994
    Inventor: John T. Wilson
  • Patent number: 4751891
    Abstract: A bow protector for protecting and cushioning the bow of watercraft such as sailboats, which includes a shaped, impact-receiving nose portion having a V-shaped inner angle for engaging the front edge of the bow and rearwardly extending arms designed to seat on opposite anterior surfaces of the bow. In a preferred embodiment the bow protector is provided with a longitudinal impact slot extending through the center of the nose portion and spaced ancillary impact slots also projecting through the nose portion and located adjacent to the central impact slot, in order to cushion impact forces received by the bow protector when the watercraft strikes a dock, another watercraft or any other relatively unyielding object. The bow protector is suspended on the bow of the watercraft by means of starboard and port elastic guy lines which extend through guy line openings provided in the bow protector and are anchored to cleats secured to the foredeck of the watercraft.
    Type: Grant
    Filed: November 17, 1986
    Date of Patent: June 21, 1988
    Inventor: John T. Wilson
  • Patent number: 4713343
    Abstract: Contaminating amounts of certain halogenated aliphatic hydrocarbons are degraded and removed from water such as drinking water and industrial waste water, by treatment of the water with a microorganism that is effective to metabolize gaseous hydrocarbons by the action of monooxygenase enzyme.
    Type: Grant
    Filed: August 29, 1985
    Date of Patent: December 15, 1987
    Assignee: The United States of America as represented by the Administrator of the U.S. Environmental Protection Agency
    Inventors: John T. Wilson, Jr., Barbara H. Wilson
  • Patent number: 4395486
    Abstract: A direct diagnosis of sickle cell anemia by a restriction endonuclease assay with an enzyme which recognizes the nucleotide base sequence CTNAG (where N is any base), such as Dde I, for the sickle cell allele (.beta..sup.s gene) through molecular hybridization. Following enzyme cleavage, the resulting DNA restriction fragments are separated by molecular weight and transferred to filter paper. A probe is utilized for hybridization that is complementary to the 5' end of the .beta. globin gene. The banding pattern of individuals with normal hemoglobin shows two bands (approximately 175 bp and 201 bp), sickle cell trait individuals exhibit an additional band (approximately 376 bp) and individuals with sickle cell anemia show the band at approximately 376 bp with a concommitant loss of the band at approximately 175 bp. Prenatal and postnatal diagnosis of sickle cell anemia is possible with the present method.
    Type: Grant
    Filed: August 19, 1981
    Date of Patent: July 26, 1983
    Assignee: Medical College of Ga. Research Inst., Inc.
    Inventors: Lois B. Wilson, John T. Wilson, Robert F. Geever
  • Patent number: 4351012
    Abstract: A circuit breaker includes a digital electronic trip unit having a microprocessor. The front panel of the trip unit includes a potentiometer connected across a reference voltage, and a numeric display device. The potentiometer is adjusted by an operator to enter a value of a parameter defining the time-current characteristic of the circuit breaker. An analog-to-digital converter receives the voltage supplied by the potentiometer and converts it to a digital quantity for use by the microcomputer in performing limit checks with the current flow through the contacts of the breaker. The microcomputer formats the converted digital value of the potentiometer voltage and supplies it to a front panel-visible numeric display so that the value of the potentiometer setting as interpreted by the microcomputer in defining the time-current trip characteristic is presented on the numeric display to provide real-time feedback to the operator as he adjusts the parameter value.
    Type: Grant
    Filed: April 15, 1980
    Date of Patent: September 21, 1982
    Assignee: Westinghouse Electric Corp.
    Inventors: Robert T. Elms, Joseph C. Engel, Bernard J. Mercier, Gary F. Saletta, John T. Wilson
  • Patent number: 4338647
    Abstract: A circuit breaker includes a microprocessor-based trip unit having an optically coupled data input/output system. A pulse transformer receives input pulses generated by the execution of instructions in said microcomputer and supplies these pulses to a plurality of optical isolators, thereby reducing the power requirements of the optically isolated interface system to a value sufficient to allow complete operating power to be supplied to the trip unit and the data input/output system from the sensing current transformers within the circuit breaker housing.
    Type: Grant
    Filed: April 15, 1980
    Date of Patent: July 6, 1982
    Assignee: Westinghouse Electric Corp.
    Inventors: John T. Wilson, John A. Wafer, Joseph C. Engel, Robert T. Elms
  • Patent number: 4335437
    Abstract: A circuit interrupter includes a digital trip unit containing a microprocessor. The circuit interrupter also includes current transformers for sensing current flow through the contacts of the interrupter and for providing operating power to the trip unit. The current transformers monitoring current flow through the breaker and control potentiometers receiving operator-entered values of the product of line voltage and power factor are connected to the microprocessor to supply it with the values needed to compute real power flow through the interrupter and to display the numeric value of this power flow. The power flow is compared to an operator-entered limit value of peak demand power, and an alarm signal is generated whenever power flow exceeds the limit value peak demand. Integration capability is also provided to calculate energy flow through the contacts in megawatt hours and to present the numeric value of this energy flow.
    Type: Grant
    Filed: April 15, 1980
    Date of Patent: June 15, 1982
    Assignee: Westinghouse Electric Corp.
    Inventors: John T. Wilson, John A. Wafer, Joseph C. Engel