Patents by Inventor John Terrig Thomas

John Terrig Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SECRETED MODULAR CALCIUM BINDING PROTEIN FOR INTRACELLULAR MODULATION OF BONE MORPHOGENETIC PROTEIN SIGNALING
    Publication number: 20110256100
    Abstract: A method for modulating Bone Morphogenetic Protein (BMP) signaling activity in a cell or tissue of a vertebrate subject is provided which comprises administering a polynucleotide or polypeptide encoding a Secreted Modular Calcium Binding Protein (SMOC) polypeptide, or a conservatively modified variant, derivative, or analog thereof, in an amount effective to activate intracellular Mitogen Activated Protein (MAP) kinase activity and to reduce BMP signaling activity in the cell or tissue of the vertebrate subject. Methods for treating joint disorders in a mammalian subject are provided.
    Type: Application
    Filed: July 31, 2009
    Publication date: October 20, 2011
    Applicant: KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: John Terrig Thomas, Malcolm C. Moos Jr., Frank Luyten