Patents by Inventor John Tew

John Tew has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090049207
    Abstract: A method of communicating with a device using a Field Device Tool (FDT) framework, such that the device operates in a process control environment and is communicatively coupled to a communication link, includes generating an instance of a scan capable device type manager (DTM) of type device that represents the device in the FDT framework, communicatively connecting the instance of the scan capable DTM to a communication channel which corresponds to the communication link, scanning the communication link to discover the device using the instance of the scan capable DTM, and obtaining an address of the discovered device at the scan capable DTM.
    Type: Application
    Filed: August 15, 2008
    Publication date: February 19, 2009
    Applicant: FISHER CONTROLS INTERNATIONAL LLC
    Inventors: Connor William Reynolds, Michael John Tewes, Mahesh Gade
  • Publication number: 20080008653
    Abstract: The present invention is directed to methods for constructing and using in vivo and in vitro models of aspects of human immunity and, in particular, construction of a human immune system model for the testing of, for example, vaccines, adjuvants, immunotherapy candidates, cosmetics, drugs, biologics and other chemicals. The present invention comprises both in vivo and in vitro models of aspects of human immunity that are useful for assessing the interaction of substances with the immune system, and thus can be used to accelerate and improve the accuracy and predictability of, for example, vaccine, drug, biologic, immunotherapy, cosmetic and chemical development. The invention is also useful for the generation of human monoclonal and polyclonal antibodies.
    Type: Application
    Filed: June 27, 2007
    Publication date: January 10, 2008
    Inventors: John Tew, Mohey Eldin El Shikh, Inderpal Singh, Eric Mishkin, Donald Drake, Haifeng Song, William Warren
  • Publication number: 20070218054
    Abstract: The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days.
    Type: Application
    Filed: December 21, 2006
    Publication date: September 20, 2007
    Inventors: Selva Sukumar, Mohey Eldin El Shikh, John Tew, Guzman Sanchez-Schmitz, Donald Drake, Luis Mosquera, Eric Mishkin, Anatoly Kachurin, Russell Higbee, Conan Li, William Warren, Heather Fahlenkamp
  • Publication number: 20060275270
    Abstract: The present invention relates to methods of constructing an integrated artificial immune system that comprises appropriate in vitro cellular and tissue constructs or their equivalents to mimic the normal tissues that interact with pathogens and vaccines in mammals. The artificial immune system can be used to test the efficacy of vaccine candidates in vitro and thus, is useful to accelerate vaccine development and testing drug and chemical interactions with the immune system.
    Type: Application
    Filed: March 15, 2006
    Publication date: December 7, 2006
    Inventors: William Warren, Guzman Sanchez-Schmitz, Russell Higbee, Heather Fahlenkamp, Donald Drake, John Tew