Abstract: Methods of enhancing efficiency of downstream chromatography steps for purification of proteins comprising: (a) passing a composition comprising a polypeptide of interest and various contaminants through an ion exchange membrane, wherein the polypeptide and the membrane have opposite charge, at operating conditions comprised of a buffer having a pH sufficiently distinct from the pi of the polypeptide to enhance the charge of the polypeptide and a low ionic strength effective to prevent the shielding of charges by buffer ions, which cause the membrane to bind the polypeptide and at least one contaminant, (b) overloading the ion exchange membrane such that at least one contaminant remains bound to the membrane while the polypeptide of interest is primarily in the effluent; (c) collecting the effluent from the ion exchange membrane comprising the polypeptide of interest; (d) subjecting the membrane effluent comprising the polypeptide of interest to a purification step of similar charge as the previous membrane,

Abstract: A heat transfer device includes a hollow metal body. The hollow body defines a wall having a thickness, an internal chamber defined at least in part by the wall, a vacuum defined in the internal chamber, a seam defined between two different portions of the wall and extending through the thickness of the wall, a brazing material applied to the seam to hermetically seal the internal chamber and maintain the vacuum in the internal chamber, an evaporation region in which heat is received in the hollow metal body, and a condenser region from which heat is discharged from the hollow metal body. The heat transfer device further includes a charge of ice within the internal chamber, the charge of ice sufficiently large to define, when in a thawed state, a working fluid drawing heat from the evaporator region and discharging heat from the condenser region in a working cycle of the heat transfer device.

Abstract: A flexible elongate structure, such as a flexible riser (10), comprising at least one layer (20) of steel wires near the surface which extend at least partly along the length of the structure, can be monitored by inducing a small, alternating magnetic field in the steel wires using an electromagnetic coil, and monitoring the magnetic flux density near the surface of the structure so as to asses the stress and hence detect if any wires have broken. By using an array of stress-measuring electromagnetic probes (24) around the structure some spatial resolution can be provided as to the location of any break in the wires.

Abstract: A heat exchanger for cooling a heat generating device including a base having a recess with a base coolant inlet opening and a base coolant outlet opening. A porous core is positioned within the recess of the base, and has a core coolant inlet opening and a core coolant outlet opening that are arranged in corresponding relation with base coolant inlet opening and a base coolant outlet opening so as to be in fluid communication. A porous gasket is pinched between the porous core and the base.

Abstract: A method of identifying components and building a bicycle is provided. Methods and products described provides component characteristics, compatibility attributes, and optionally multiple functionality of components in a single component database record. Methods and products described also provide adjustability of component lists for bike building as components are selected. Methods and products described also provide simplification of data entry as new products are added to the database.

Abstract: An evaporator includes an enclosure having a fluid inlet manifold and a vapor outlet manifold. At least one blind passageway is arranged within the enclosure so as to open into a portion of the vapor outlet manifold. The interior surface of the enclosure that defines each passageway is covered with a capillary wick. A porous valve is arranged in fluid communication between the fluid inlet manifold and a blind end of the at least one blind passageway.

Abstract: In a railway line, thermally-induced stresses are a factor for both rail breaks and rail buckling. These stresses are in the longitudinal direction. A nondestructive measuring technique enables the residual stress in a rail to be determined, and hence the thermally-induced stress. An electromagnetic probe is used to measure the stresses in the rail web in the vertical direction, and in the direction parallel to the longitudinal axis. The residual stress in the longitudinal direction can be deduced from the measured stress in the vertical direction; hence the thermally-induced stress can be determined.

Abstract: A flexible heat pipe is disclosed for use with evaporator and condenser elements for removing heat from electronic components. The flexible heat pipe comprises a bellows member fixed at one end to a condenser member and at an opposite end to an evaporator member. A cable artery is disposed within the bellows and is fixed at one end to the evaporator, and slidingly engages the condenser at the opposite end. The bellows acts as a flexible vapor envelope, and the cable artery acts as a flexible wick for directing condensed working fluid from the condenser back to the evaporator. The sliding connection between the cable artery and the condenser allows relative axial movement, and the inherent flexibility of the cable artery allows relative lateral movement. Thus, the condenser and evaporator can move in all directions with respect to each other, which can provide desired vibration isolation of the two components.

Abstract: The onset of rolling contact fatigue in an object may be detected by measuring the residual stresses in the surface of the object, and monitoring changes in their magnitude or their direction. The values of residual stresses in the surface are those averaged over a depth that may be in the range say 0.1 mm to 8.0 mm, for example about 2.5 mm. For ferromagnetic objects such as rails, the method may utilize an electromagnetic probe. Prior to rolling contact fatigue the surface stresses are compressive, and the onset of rolling contact fatigue may be characterized by a marked decrease of the stress in the generally transverse direction.

Abstract: A heat exchanger for cooling a heat generating device including a base having a recess with a base coolant inlet opening and a base coolant outlet opening. A porous core is positioned within the recess of the base, and has a core coolant inlet opening and a core coolant outlet opening that are arranged in corresponding relation with base coolant inlet opening and a base coolant outlet opening so as to be in fluid communication. A porous gasket is pinched between the porous core and the base.

Abstract: An evaporator includes an enclosure having a fluid inlet manifold and a vapor outlet manifold. At least one blind passageway is arranged within the enclosure so as to open into a portion of the vapor outlet manifold. The interior surface of the enclosure that defines each passageway is covered with a capillary wick. A porous valve is arranged in fluid communication between the fluid inlet manifold and a blind end of the at least one blind passageway.

Abstract: A burn-in testing cooling system includes a heat pipe having a tubular body. A capillary wick is disposed on an evaporator portion of the tubular body, and a base seals off the evaporator portion. The base is sized and shaped so as to be releasably thermally engaged with a semiconductor device during burn-in testing. A working fluid is disposed within the heat pipe in sufficient quantity to at least saturate the wick. A hollow tube is coiled around the exterior surface of the heat pipe such that a first set of interior coils are formed adjacent to the exterior surface. These interior coils are brazed to the exterior surface so as to enhance their thermal interface with the heat pipe. A second set of coils are wrapped around the first set of coils, in overlying relation to them.

Abstract: A cooling system for a semiconductor device burn-in test station includes one or more evaporators arranged in close thermal proximity to a semiconductor device. Each evaporator includes a chambered enclosure having a capillary wick disposed on the walls of the enclosure that define the chamber. A condenser is arranged in fluid communication with each chamber, and a pump is arranged in flow communication between each evaporator and the condenser so as to circulate a coolant liquid between a pool of the coolant liquid that is maintained within the chambered enclosure and the condenser.

Abstract: A burn-in testing cooling system including an evaporator comprising an upright tubular body having an interior surface and a central passageway with a wick disposed on the interior surface of the body that defines the central passageway. A base seals off the central passageway, with an inlet port arranged in flow communication with an upper portion of the central passageway and an outlet port arranged in flow communication with a lower portion of the central passageway. A coolant is disposed within the central passageway. A condenser is arranged in flow communication with the evaporator.

Abstract: The onset of rolling contact fatigue in an object may be detected by measuring the residual stresses in the surface of the object, and monitoring changes in their magnitude or their direction. The values of residual stresses in the surface are those averaged over a depth that may be in the range say 0.1 mm to 8.0 mm, for example about 2.5 mm. For ferromagnetic objects such as rails, the method may utilise an electromagnetic probe. Prior to rolling contact fatigue the surface stresses are compressive, and the onset of rolling contact fatigue may be characterised by a marked decrease of the stress in the generally transverse direction.

Abstract: A continuous pusher furnace includes a product carrier assembly forming a traveling gas barrier. The product carrier assembly comprises a pusher plate disposed to receive product thereon and a gas barrier extending upwardly from the pusher plate. The perimeter of the gas barrier is sized and configured to fit within a vestibule between heating chambers in the furnace with a clearance gap with the vestibule selected to increase a gas flow velocity through the vestibule sufficient to overcome a gas diffusion velocity through the vestibule in a direction opposite to the gas flow. In this manner, gas is unable to diffuse into an upstream heating chamber. In an alternative embodiment, an exhaust outlet may also be provided in the vestibule or chamber to exhaust gas from upstream and downstream heating chambers from the furnace.